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Phylogenetic comparative methods explore the relationships between quantitative traits adjusting for shared evolutionary history. This adjustment often occurs through a Brownian diffusion process along the branches of the phylogeny that…

Methodology · Statistics 2017-01-27 Max R. Tolkoff , Michael L. Alfaro , Guy Baele , Philippe Lemey , Marc A. Suchard

We present a provable, sampling-based approach for generating compact Convolutional Neural Networks (CNNs) by identifying and removing redundant filters from an over-parameterized network. Our algorithm uses a small batch of input data…

Machine Learning · Computer Science 2020-03-24 Lucas Liebenwein , Cenk Baykal , Harry Lang , Dan Feldman , Daniela Rus

Motivated by genome-wide association studies, we consider a standard linear model with one additional random effect in situations where many predictors have been collected on the same subjects and each predictor is analyzed separately.…

Applications · Statistics 2013-04-24 Matti Pirinen , Peter Donnelly , Chris C. A. Spencer

Phylogenetic comparative methods correct for shared evolutionary history among a set of non-independent organisms by modeling sample traits as arising from a diffusion process along on the branches of a possibly unknown history. To…

Applications · Statistics 2020-09-30 Paul Bastide , Lam Si Tung Ho , Guy Baele , Philippe Lemey , Marc A Suchard

We introduce a biologically natural, mathematically tractable model of random phylogenetic network to describe evolution in the presence of hybridization. One of the features of this model is that the hybridization rate of the lineages…

Probability · Mathematics 2024-02-27 François Bienvenu , Jean-Jil Duchamps

We present an efficient phylogenetic reconstruction algorithm allowing insertions and deletions which provably achieves a sequence-length requirement (or sample complexity) growing polynomially in the number of taxa. Our algorithm is…

Probability · Mathematics 2013-02-25 Constantinos Daskalakis , Sebastien Roch

In past decades, Gaussian processes has been widely applied in studying trait evolution using phylogenetic comparative analysis. In particular, two members of Gaussian processes: Brownian motion and Ornstein-Uhlenbeck process, have been…

Methodology · Statistics 2018-08-20 Dwueng-Chwuan Jhwueng

We introduce a new phylogenetic reconstruction algorithm which, unlike most previous rigorous inference techniques, does not rely on assumptions regarding the branch lengths or the depth of the tree. The algorithm returns a forest which is…

Populations and Evolution · Quantitative Biology 2011-09-30 Constantinos Daskalakis , Elchanan Mossel , Sebastien Roch

Biological data objects often have both of the following features: (i) they are functions rather than single numbers or vectors, and (ii) they are correlated due to phylogenetic relationships. In this paper we give a flexible statistical…

Quantitative Methods · Quantitative Biology 2012-12-20 Nick S. Jones , John Moriarty

Biological phenotypes are products of complex evolutionary processes in which selective forces influence multiple biological trait measurements in unknown ways. Phylogenetic factor analysis disentangles these relationships across the…

The increasing availability of population-level allele frequency data across one or more related populations necessitates the development of methods that can efficiently estimate population genetics parameters, such as the strength of…

Computation · Statistics 2017-11-09 Jeffrey J. Gory , Radu Herbei , Laura S. Kubatko

Gradients of probabilistic model likelihoods with respect to their parameters are essential for modern computational statistics and machine learning. These calculations are readily available for arbitrary models via automatic…

Populations and Evolution · Quantitative Biology 2023-06-06 Mathieu Fourment , Christiaan J. Swanepoel , Jared G. Galloway , Xiang Ji , Karthik Gangavarapu , Marc A. Suchard , Frederick A. Matsen

Evolutionary Computation algorithms have been used to solve optimization problems in relation with architectural, hyper-parameter or training configuration, forging the field known today as Neural Architecture Search. These algorithms have…

Neural and Evolutionary Computing · Computer Science 2024-02-06 Javier Poyatos , Daniel Molina , Aitor Martínez , Javier Del Ser , Francisco Herrera

Phylogenetic networks provide a means of describing the evolutionary history of sets of species believed to have undergone hybridization or gene flow during their evolution. The mutation process for a set of such species can be modeled as a…

Populations and Evolution · Quantitative Biology 2022-11-23 Travis Barton , Elizabeth Gross , Colby Long , Joseph Rusinko

Phylogenetic networks are necessary to represent the tree of life expanded by edges to represent events such as horizontal gene transfers, hybridizations or gene flow. Not all species follow the paradigm of vertical inheritance of their…

Populations and Evolution · Quantitative Biology 2016-02-15 Claudia Solís-Lemus , Cécile Ané

In recent years the importance of finding a meaningful pattern from huge datasets has become more challenging. Data miners try to adopt innovative methods to face this problem by applying feature selection methods. In this paper we propose…

Machine Learning · Computer Science 2014-03-11 Mehdi Naseriparsa , Amir-masoud Bidgoli , Touraj Varaee

Phylogenetic inference, the task of reconstructing how related sequences evolved from common ancestors, is a central objective in evolutionary genomics. The current state-of-the-art methods exploit probabilistic models of sequence evolution…

Populations and Evolution · Quantitative Biology 2026-02-19 Luc Blassel , Noémie Sauvage , Pierre Barrat-Charlaix , Bastien Boussau , Nicolas Lartillot , Laurent Jacob

We propose a new formulation for pruning convolutional kernels in neural networks to enable efficient inference. We interleave greedy criteria-based pruning with fine-tuning by backpropagation - a computationally efficient procedure that…

Machine Learning · Computer Science 2017-06-12 Pavlo Molchanov , Stephen Tyree , Tero Karras , Timo Aila , Jan Kautz

In this paper we address the use of rare event computation techniques to estimate small over-threshold probabilities of observables in determin-istic dynamical systems. We demonstrate that the genealogical particle analysis algorithms can…

Statistical Mechanics · Physics 2016-09-21 Jeroen Wouters , Freddy Bouchet

Quartet Reconstruction, the task of recovering a phylogenetic tree from smaller trees on four species called \textit{quartets}, is a well-studied problem in theoretical computer science with far-reaching connections to statistics, graph…

Data Structures and Algorithms · Computer Science 2026-04-21 Dionysis Arvanitakis , Vaggos Chatziafratis , Yiyuan Luo , Konstantin Makarychev