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Related papers: Optimal Strategies for Virus Propagation

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Cells use temporal dynamical patterns to transmit information via signaling pathways. As optimality with respect to the environment plays a fundamental role in biological systems, organisms have evolved optimal ways to transmit information.…

Biological Physics · Physics 2016-12-21 Yoshihiko Hasegawa

The incubation period of a disease is the time between an initiating pathologic event and the onset of symptoms. For typhoid fever, polio, measles, leukemia and many other diseases, the incubation period is highly variable. Some affected…

Populations and Evolution · Quantitative Biology 2017-06-01 Bertrand Ottino-Loffler , Jacob G. Scott , Steven H. Strogatz

Active cellular transport is a fundamental mechanism for protein and vesicle delivery, cell cycle and molecular degradation. Viruses can hijack the transport system and use it to reach the nucleus. Most transport processes consist of…

Quantitative Methods · Quantitative Biology 2009-11-13 T. Lagache , D. Holcman

Efficient testing and vaccination protocols are critical aspects of epidemic management. To study the optimal allocation of limited testing and vaccination resources in a heterogeneous contact network of interacting susceptible, recovered,…

Populations and Evolution · Quantitative Biology 2026-05-12 Mingtao Xia , Lucas Böttcher , Tom Chou

In this paper, we study an optimal control problem of a communicable disease in a prison population. In order to control the spread of the disease inside a prison, we consider an active case-finding strategy, consisting on screening a…

Optimization and Control · Mathematics 2020-11-06 Pedro Gajardo , Victor Riquelme , Diego Vicencio

In this paper, we study the dynamics of epidemic processes taking place in temporal and adaptive networks. Building on the activity-driven network model, we propose an adaptive model of epidemic processes, where the network topology…

Social and Information Networks · Computer Science 2018-02-27 Masaki Ogura , Victor M. Preciado , Naoki Masuda

Chlamydiae are bacteria with an interesting unusual developmental cycle. A single bacterium in its infectious form (elementary body, EB) enters the host cell, where it converts into its dividing form (reticulate body, RB), and divides by…

Populations and Evolution · Quantitative Biology 2023-06-06 Péter Kevei , Máté Szalai

Human behaviour strongly influences the spread of infectious diseases: understanding the interplay between epidemic dynamics and adaptive behaviours is essential to improve response strategies to epidemics, with the goal of containing the…

Physics and Society · Physics 2024-08-21 Marco Mancastroppa , Alessandro Vezzani , Vittoria Colizza , Raffaella Burioni

We propose a versatile model with a flexible choice of control for an early-pandemic outbreak prevention when vaccine/drug is not yet available. At that stage, control is often limited to non-medical interventions like social distancing and…

Optimization and Control · Mathematics 2024-06-14 Alexandra Smirnova , Xiaojing Ye

We propose and investigate a delayed model that studies the relationship between HIV and the immune system during the natural course of infection and in the context of antiviral treatment regimes. Sufficient criteria for local asymptotic…

Optimization and Control · Mathematics 2018-03-19 Diana Rocha , Cristiana J. Silva , Delfim F. M. Torres

Viral kinetics have been extensively studied in the past through the use of spatially well-mixed ordinary differential equations describing the time evolution of the diseased state. However, emerging spatial structures such as localized…

Cell Behavior · Quantitative Biology 2024-04-02 Catherine Beauchemin

Evolution of disease in a large population is a function of the top-down policy measures from a centralized planner, as well as the self-interested decisions (to be socially active) of individual agents in a large heterogeneous population.…

Optimization and Control · Mathematics 2022-06-07 S. Yagiz Olmez , Shubham Aggarwal , Jin Won Kim , Erik Miehling , Tamer Başar , Matthew West , Prashant G. Mehta

We introduce a model of parasite infection in a cell population, where cells can be infected, either at birth through maternal transmission, from a contact with the parasites reservoir, or because of the parasites released in the cell…

Probability · Mathematics 2021-11-10 Charline Smadi

The increase in the connectivity between hosts in recent times has facilitated the emergence of more aggressive mutant viral strains, making their containment and eradication significantly more challenging compared to the original variants.…

Populations and Evolution · Quantitative Biology 2025-02-27 Javier López-Pedrares , M. Elena Vázquez-Cendón , Alberto P. Muñuzuri

We review the optimal control of systems modeling the dynamics of tuberculosis. Time dependent control functions are introduced in the mathematical models, representing strategies for the improvement of the treatment and cure of active…

Optimization and Control · Mathematics 2015-08-18 Cristiana J. Silva , Delfim F. M. Torres

We consider a model for an epidemic in a population that occupies geographically distinct locations. The disease is spread within subpopulations by contacts between infective and susceptible individuals, and is spread between subpopulations…

Probability · Mathematics 2016-02-15 R. McVinish , P. K. Pollett , A. Shausan

Authors propose a conceptual model of participation in viral diffusion process composed of four stages: awareness, infection, engagement and action. To verify the model it has been applied and studied in the virtual social chat environment…

Social and Information Networks · Computer Science 2013-03-12 Jarosław Jankowski , Sylwia Ciuberek , Anita Zbieg , Radosław Michalski

Understanding the spread of infectious diseases requires integrating movement, physical constraints, and spatial configurations into epidemiological models. In this study, we investigate how particle diffusivity, hardcore interactions, and…

Other Condensed Matter · Physics 2025-06-17 Kaito Takahashi , Makiko Sasada , Takuma Akimoto

This article considers the minimization of the total number of infected individuals over the course of an epidemic in which the rate of infectious contacts can be reduced by time-dependent nonpharmaceutical interventions. The societal and…

Optimization and Control · Mathematics 2023-03-16 Tom Britton , Lasse Leskelä

Computer infections such as viruses and worms spread over networks of contacts between computers, with different types of networks being exploited by different types of infections. Here we analyze the structures of several of these…

Networking and Internet Architecture · Computer Science 2007-05-23 Justin Balthrop , Stephanie Forrest , M. E. J. Newman , Matthew M. Williamson