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Responding appropriately to the detections of a sequential change detector requires knowledge of the rate at which false positives occur in the absence of change. Setting detection thresholds to achieve a desired false positive rate is…

Methodology · Statistics 2022-02-18 Oliver Cobb , Arnaud Van Looveren , Janis Klaise

Permutation tests have been proposed by Albert et al. (2015) to detect dependence between point processes, modeling in particular spike trains, that is the time occurrences of action potentials emitted by neurons. Our present work focuses…

Statistics Theory · Mathematics 2025-11-04 Josué Tchouanti , Éva Löcherbach , Patricia Reynaud-Bouret , Etienne Tanré

We provide an empirical process theory for locally stationary processes over nonsmooth function classes. An important novelty over other approaches is the use of the flexible functional dependence measure to quantify dependence. A…

Statistics Theory · Mathematics 2021-08-20 Nathawut Phandoidaen , Stefan Richter

Repeated occurrences of serial firing sequences of a group of neurons with fixed time delays between neurons are observed in many experiments involving simultaneous recordings from multiple neurons. Such temporal patterns are potentially…

Neurons and Cognition · Quantitative Biology 2008-09-01 C. O. Diekman , P. S. Sastry , K. P. Unnikrishnan

The problem of detecting changes in firing patterns in neural data is studied. The problem is formulated as a quickest change detection problem. Important algorithms from the literature are reviewed. A new algorithmic technique is discussed…

Signal Processing · Electrical Eng. & Systems 2018-09-05 Taposh Banerjee , Stephen Allsop , Kay M. Tye , Demba Ba , Vahid Tarokh

This paper considers the change point detection problem under dependent samples. In particular, we provide performance guarantees for the MMD-CUSUM test under exponentially $\alpha$, $\beta$, and fast $\phi$-mixing processes, which…

Systems and Control · Electrical Eng. & Systems 2024-05-13 Hao Chen , Abhishek Gupta , Yin Sun , Ness Shroff

Extracting and detecting spike activities from the fluorescence observations is an important step in understanding how neuron systems work. The main challenge lies in that the combination of the ambient noise with dynamic baseline…

Neurons and Cognition · Quantitative Biology 2019-02-01 Zhuangkun Wei , Bin Li , Weisi Guo , Wenxiu Hu , Chenglin Zhao

Deterministic model predictive control (MPC), while powerful, is often insufficient for effectively controlling autonomous systems in the real-world. Factors such as environmental noise and model error can cause deviations from the expected…

Optimization and Control · Mathematics 2024-07-29 Alex Oshin , Hassan Almubarak , Evangelos A. Theodorou

Modelling the dynamics of interactions in a neuronal ensemble is an important problem in functional connectivity research. One popular framework is latent factor models (LFMs), which have achieved notable success in decoding neuronal…

Methodology · Statistics 2023-05-18 Meixi Chen , Martin Lysy , David Moorman , Reza Ramezan

Background: Measures of spike train synchrony are widely used in both experimental and computational neuroscience. Time-scale independent and parameter-free measures, such as the ISI-distance, the SPIKE-distance and SPIKE-synchronization,…

Data Analysis, Statistics and Probability · Physics 2017-05-31 Eero Satuvuori , Mario Mulansky , Nebojsa Bozanic , Irene Malvestio , Fleur Zeldenrust , Kerstin Lenk , Thomas Kreuz

Recently, the SPIKE-distance has been proposed as a parameter-free and time-scale independent measure of spike train synchrony. This measure is time-resolved since it relies on instantaneous estimates of spike train dissimilarity. However,…

Data Analysis, Statistics and Probability · Physics 2012-12-11 Thomas Kreuz , Daniel Chicharro , Conor Houghton , Ralph G Andrzejak , Florian Mormann

Sparse sequences of neural spikes are posited to underlie aspects of working memory, motor production, and learning. Discovering these sequences in an unsupervised manner is a longstanding problem in statistical neuroscience. Promising…

Machine Learning · Statistics 2020-10-13 Alex H. Williams , Anthony Degleris , Yixin Wang , Scott W. Linderman

Spike generation in neurons produces a temporal point process, whose statistics is governed by intrinsic phenomena and the external incoming inputs to be coded. In particular, spike-evoked adaptation currents support a slow temporal process…

Neurons and Cognition · Quantitative Biology 2016-10-31 Eugenio Urdapilleta

The intrinsic mode function (IMF) provides adaptive function bases for nonlinear and non-stationary time series data. A fast convergent iterative method is introduced in this paper to find the IMF components of the data, the method is…

Numerical Analysis · Computer Science 2008-09-11 Louis Yu Lu

Change-point detection and locally stationary time series modeling are two major approaches for the analysis of non-stationary data. The former aims to identify stationary phases by detecting abrupt changes in the dynamics of a time series…

Methodology · Statistics 2026-01-16 Wai Leong Ng , Xinyi Tang , Mun Lau Cheung , Jiacheng Gao , Chun Yip Yau , Holger Dette

We briefly review and highlight the consequences of rigorous and exact results obtained in \cite{cessac:10}, characterizing the statistics of spike trains in a network of leaky Integrate-and-Fire neurons, where time is discrete and where…

Adaptation and Self-Organizing Systems · Physics 2010-08-31 Bruno Cessac , Hassan Nasser , Juan-Carlos Vasquez

Fluctuation theorems (FTs) quantify the thermodynamic reversibility of a system, and for deterministic systems they are defined in terms of the dissipation function. However, in a nonequilibrium steady state of deterministic dynamics, the…

Statistical Mechanics · Physics 2026-03-24 Stephen Sanderson , Charlotte F. Petersen , Debra J. Searles

Spiking neural networks (SNNs) promise low-power event-driven computation for temporally rich tasks, but commonly used neuron models often trade off gradient-based trainability, dynamical richness, and high activity sparsity. These…

Neural and Evolutionary Computing · Computer Science 2026-05-13 Alex Fulleda-Garcia , Saray Soldado-Magraner , Josep Maria Margarit-Taulé

Simultaneous recordings from many neurons hide important information and the connections characterizing the network remain generally undiscovered despite the progresses of statistical and machine learning techniques. Discerning the presence…

Applications · Statistics 2019-03-21 Pietro Verzelli , Laura Sacerdote

Infrequent Metadynamics is a popular method to obtain the rates of long timescale processes from accelerated simulations. The inference procedure is based on rescaling the first-passage times of Metadynamics trajectories using a…

Chemical Physics · Physics 2025-03-04 Ofir Blumer , Shlomi Reuveni , Barak Hirshberg