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Wavefront shaping systems aim to image deep into scattering tissue by reshaping incoming and outgoing light to correct aberrations caused by tissue inhomogeneity However, the desired modulation depends on the unknown tissue structure and…

Optics · Physics 2026-01-14 Sagi Monin , Marina Alterman , Anat Levin

We study the focusing of light through random photonic materials using wavefront shaping. We explore a novel approach namely binary amplitude modulation. To this end, the light incident to a random photonic medium is spatially divided into…

The Zernike wavefront sensor (ZWFS) stands out as one of the most sensitive optical systems for measuring the phase of an incoming wavefront, reaching photon efficiencies close to the fundamental limit. This quality, combined with the fact…

In this manuscript we demonstrate a method to reconstruct the wavefront of focused beams from a measured diffraction pattern behind a diffracting mask in real-time. The phase problem is solved by means of a neural network, which is trained…

Image and Video Processing · Electrical Eng. & Systems 2021-04-07 Jonathon White , Sici Wang , Wilhelm Eschen , Jan Rothhardt

We propose and implement a broadband, compact, and low-cost wavefront sensing scheme by simply placing a thin diffuser in the close vicinity of a camera. The local wavefront gradient is determined from the local translation of the speckle…

Optics · Physics 2018-01-23 Pascal Berto , Hervé Rigneault , Marc Guillon

Mobile photography is often limited by complex, lens-specific optical aberrations. While recent deep learning methods approach this as an end-to-end deblurring task, these "black-box" models lack explicit optical modeling and can…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Kartik Jhawar , Tamo Sancho Miguel Tandoc , Khoo Jun Xuan , Wang Lipo

Sample-induced aberrations and optical imperfections limit the resolution of fluorescence microscopy. Phase diversity is a powerful technique that leverages complementary phase information in sequentially acquired images with deliberately…

Imaging with optical resolution through highly scattering media is a long sought-after goal with important applications in deep tissue imaging. Although being the focus of numerous works, this goal was considered impractical until recently.…

Optics · Physics 2012-02-10 Ori Katz , Eran Small , Yaron Silberberg

Shack Hartmann wavefront sensor is a two dimensional array of lenslets which is used to detect the incoming phase distorted wavefront through local tilt measurements made by recording the spot pattern near the focal plane. Wavefront…

Instrumentation and Methods for Astrophysics · Physics 2011-08-16 Akondi Vyas , M B Roopashree , B Raghavendra Prasad

Confining light illumination in the three dimensions of space is a challenge for various applications. Among these, optogenetic methods developed for live experiments in cell biology would benefit from such a localized illumination as it…

Context: Telescopes like the Extremely Large Telescope (ELT) and the Giant Magellan Telescope (GMT) will be used together with extreme adaptive optics (AO) instruments to directly image Earth-like planets. The AO systems will need to…

Instrumentation and Methods for Astrophysics · Physics 2024-01-17 Sebastiaan Y. Haffert

Wavefront shaping is a powerful technique that can be used to focus light through scattering media, which can be important for imaging through scattering samples such as tissue. The method is based on the assumption that the field at the…

Zernike polynomials are widely used to describe the wavefront phase as they are well suited to the circular geometry of various optical apertures. Non-conventional optical systems, such as future large optical telescopes with highly…

Instrumentation and Methods for Astrophysics · Physics 2018-09-27 Pierre Janin-Potiron , Patrice Martinez , Marcel Carbillet

From the earth's crust to the human brain, remitted waves are used for sensing and imaging in a diverse range of diffusive media. Separating the source and detector increases the penetration depth of remitted light, yet rapidly decreases…

Three-photon (3P) microscopy is getting traction due to its superior performance in deep tissues. Yet, aberrations and light scattering still pose one of the main limitations in the attainable depth ranges for high-resolution imaging. Here,…

Light scattering and aberrations limit optical microscopy in biological tissue, which motivates the development of adaptive optics techniques. Here, we develop a method for adaptive optics with reflected light and deep neural networks…

Optics · Physics 2020-07-28 Ivan Vishniakou , Johannes D. Seelig

Spatial mode sorting has come to prominence as an optical processing modality capable of saturating fundamental limits to numerous sensing tasks including wavefront sensing, coronagraphy, and superresolution imaging. But despite their…

Optics · Physics 2025-10-28 Jacob Trzaska , Amit Ashok

Scattering often limits the controlled delivery of light in applications such as biomedical imaging, optogenetics, optical trapping, and fiber-optic communication or imaging. Such scattering can be controlled by appropriately shaping the…

Optics · Physics 2019-02-19 Alex Turpin , Ivan Vishniakou , Johannes D. Seelig

The challenge of imaging low-density objects in an electron microscope without causing beam damage is significant in modern TEM. This is especially true for life science imaging, where the sample, rather than the instrument, still…

Optics · Physics 2025-01-29 Francisco Vega Ibáñez , Jo Verbeeck

We show optical waves passing through a nanophotonic medium can perform artificial neural computing. Complex information, is encoded in the wave front of an input light. The medium transforms the wave front to realize sophisticated…

Optics · Physics 2019-06-11 Erfan Khoram , Ang Chen , Dianjing Liu , Lei Ying , Qiqi Wang , Ming yuan , Zongfu Yu