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A biopsy is the only diagnostic procedure for accurate histological confirmation of breast cancer. When sonographic placement is not feasible, a Magnetic Resonance Imaging(MRI)-guided biopsy is often preferred. The lack of real-time imaging…

Lesion Segmentation in PET/CT scans is an essential part of modern oncological workflows. To address the challenges of time-intensive manual annotation and high inter-observer variability, the autoPET challenge series seeks to advance…

Image and Video Processing · Electrical Eng. & Systems 2025-09-03 Junwei Huang , Yingqi Hao , Yitong Luo , Ziyu Wang , Mingxuan Liu , Yifei Chen , Yuanhan Wang , Lei Xiang , Qiyuan Tian

This paper describes the design, manufacture, and performance of a highly dexterous, low-profile, 7 Degree-of-Freedom (DOF) robotic arm for CT-guided percutaneous needle biopsy. Direct CT guidance allows physicians to localize tumours…

Robotics · Computer Science 2022-03-18 Dimitri A. Schreiber , Daniel B. Shak , Alexander M. Norbash , Michael C. Yip

Automated segmentation tools often encounter accuracy and adaptability issues when applied to images of different pathology. The purpose of this study is to explore the feasibility of building a workflow to efficiently route images to…

Image and Video Processing · Electrical Eng. & Systems 2024-05-06 Peilong Wang , Timothy L. Kline , Andy D. Missert , Cole J. Cook , Matthew R. Callstrom , Alex Chan , Robert P. Hartman , Zachary S. Kelm , Panagiotis Korfiatis

In 2010, gynecologic malignancies were the 4th leading cause of death in U.S. women and for patients with extensive primary or recurrent disease, treatment with interstitial brachytherapy may be an option. However, brachytherapy requires…

Systems and Control · Computer Science 2014-04-25 Xiaojun Chen , Jan Egger

Tissue biopsy is the gold standard for diagnosing many diseases, involving the extraction of diseased tissue for histopathology analysis by expert pathologists. However, this procedure has two main limitations: 1) Manual sampling through…

Robotics · Computer Science 2025-09-03 Fanxin Wang , Yikun Cheng , Chuyuan Tao , Rohit Bhargava , Thenkurussi Kesavadas

Lesion segmentation in PET/CT imaging is essential for precise tumor characterization, which supports personalized treatment planning and enhances diagnostic precision in oncology. However, accurate manual segmentation of lesions is…

Image and Video Processing · Electrical Eng. & Systems 2024-09-19 Hamza Kalisch , Fabian Hörst , Ken Herrmann , Jens Kleesiek , Constantin Seibold

Whole-body PET/CT is a cornerstone of oncological imaging, yet accurate lesion segmentation remains challenging due to tracer heterogeneity, physiological uptake, and multi-center variability. While fully automated methods have advanced…

Computer Vision and Pattern Recognition · Computer Science 2025-09-01 Maximilian Rokuss , Yannick Kirchhoff , Fabian Isensee , Klaus H. Maier-Hein

The escalating global cancer burden underscores the critical need for precise diagnostic tools in oncology. This research employs deep learning to enhance lesion segmentation in PET/CT imaging, utilizing a dataset of 900 whole-body…

Computer Vision and Pattern Recognition · Computer Science 2024-09-17 Jiayi Liu , Qiaoyi Xue , Youdan Feng , Tianming Xu , Kaixin Shen , Chuyun Shen , Yuhang Shi

PET and CT are two modalities widely used in medical image analysis. Accurately detecting and segmenting lymphomas from these two imaging modalities are critical tasks for cancer staging and radiotherapy planning. However, this task is…

Image and Video Processing · Electrical Eng. & Systems 2021-04-28 Ling Huang , Su Ruan , Pierre Decazes , Thierry Denoeux

Lymphoma detection and segmentation from whole-body Positron Emission Tomography/Computed Tomography (PET/CT) volumes are crucial for surgical indication and radiotherapy. Designing automatic segmentation methods capable of effectively…

Image and Video Processing · Electrical Eng. & Systems 2021-08-29 Ling Huang , Thierry Denoeux , David Tonnelet , Pierre Decazes , Su Ruan

The diagnostic value of biopsies is highly dependent on the placement of needles. Robotic trajectory guidance has been shown to improve needle positioning, but feedback for real-time navigation is limited. Haptic display of needle tip…

Image-guided minimally invasive robotic surgery is commonly employed for tasks such as needle biopsies or localized therapies. However, the nonlinear deformation of various tissue types presents difficulties for surgeons in achieving…

Signal Processing · Electrical Eng. & Systems 2024-09-10 Fanxin Wang , Yikun Cheng , Sudipta S Mukherjee , Rohit Bhargava , Thenkurussi Kesavadas

Computed tomography (CT)-guided needle biopsies are critical for diagnosing a range of conditions, including lung cancer, but present challenges such as limited in-bore space, prolonged procedure times, and radiation exposure. Robotic…

Purpose: This study compares two augmented reality (AR)-guided imaging workflows, one based on ultrasound shape completion and the other on cone-beam computed tomography (CBCT), for planning and executing lumbar needle interventions. The…

Human-Computer Interaction · Computer Science 2026-03-05 Tianyu Song , Feng Li , Felix Pabst , Miruna-Alexandra Gafencu , Yuan Bi , Ulrich Eck , Nassir Navab

BrainLesion Suite is a versatile toolkit for building modular brain lesion image analysis pipelines in Python. Following Pythonic principles, BrainLesion Suite is designed to provide a 'brainless' development experience, minimizing…

The use of automatic systems in the analysis of medical images has proven to be very useful to radiologists, especially in the framework of screening programs, in which radiologists make their first diagnosis on the basis of images only,…

Synthetic biology brings together concepts and techniques from engineering and biology. In this field, computer-aided design (CAD) is necessary in order to bridge the gap between computational modeling and biological data. An application…

Molecular Networks · Quantitative Biology 2009-07-24 Deepak Chandran , Frank T. Bergmann , Herbert M. Sauro

Accurate detection and segmentation of diffuse large B-cell lymphoma (DLBCL) from PET images has important implications for estimation of total metabolic tumor volume, radiomics analysis, surgical intervention and radiotherapy. Manual…

Image and Video Processing · Electrical Eng. & Systems 2024-03-13 Shadab Ahamed , Natalia Dubljevic , Ingrid Bloise , Claire Gowdy , Patrick Martineau , Don Wilson , Carlos F. Uribe , Arman Rahmim , Fereshteh Yousefirizi

Prostate cancer diagnosis continues to encounter challenges, often due to imprecise needle placement in standard biopsies. Several control strategies have been developed to compensate for needle tip prediction inaccuracies, however none…

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