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Statistical hypothesis tests typically use prespecified sample sizes, yet data often arrive sequentially. Interim analyses invalidate classical error guarantees, while existing sequential methods require rigid testing preschedules or incur…

Methodology · Statistics 2026-02-17 Chris Holmes , Stephen Walker

Despite their importance in supporting experimental conclusions, standard statistical tests are often inadequate for research areas, like the life sciences, where the typical sample size is small and the test assumptions difficult to…

Methodology · Statistics 2011-04-15 Pietro Berkes , Jozsef Fiser

Clustering is part of unsupervised analysis methods that consist in grouping samples into homogeneous and separate subgroups of observations also called clusters. To interpret the clusters, statistical hypothesis testing is often used to…

Methodology · Statistics 2022-10-25 Benjamin Hivert , Denis Agniel , Rodolphe Thiébaut , Boris P Hejblum

In the problem of classical group testing one aims to identify a small subset (of size $d$) diseased individuals/defective items in a large population (of size $n$). This process is based on a minimal number of suitably-designed group tests…

Information Theory · Computer Science 2022-09-26 Xiwei Cheng , Sidharth Jaggi , Qiaoqiao Zhou

Robust classification algorithms have been developed in recent years with great success. We take advantage of this development and recast the classical two-sample test problem in the framework of classification. Based on the estimates of…

Statistics Theory · Mathematics 2019-09-18 Haiyan Cai , Bryan Goggin , Qingtang Jiang

We consider a new group testing model wherein each item is a binary random variable defined by an a priori probability of being defective. We assume that each probability is small and that items are independent, but not necessarily…

Information Theory · Computer Science 2018-07-24 Tongxin Li , Chun Lam Chan , Wenhao Huang , Tarik Kaced , Sidharth Jaggi

In multigroup data settings with small within-group sample sizes, standard $F$-tests of group-specific linear hypotheses can have low power, particularly if the within-group sample sizes are not large relative to the number of explanatory…

Methodology · Statistics 2022-03-25 Andrew McCormack , Peter Hoff

Hierarchically-organized data arise naturally in many psychology and neuroscience studies. As the standard assumption of independent and identically distributed samples does not hold for such data, two important problems are to accurately…

Statistics Theory · Mathematics 2018-09-03 Irene Dowding , Stefan Haufe

While there exists several inferential methods for analyzing functional data in factorial designs, there is a lack of statistical tests that are valid (i) in general designs, (ii) under non-restrictive assumptions on the data generating…

Methodology · Statistics 2023-06-28 Merle Munko , Marc Ditzhaus , Markus Pauly , Łukasz Smaga , Jin-Ting Zhang

We derive a new class of statistical tests for generalized linear models based on thresholding point estimators. These tests can be employed whether the model includes more parameters than observations or not. For linear models, our tests…

Methodology · Statistics 2018-03-14 Sylvain Sardy , Caroline Giacobino , Jairo Diaz-Rodriguez

Genome-wide association analysis has generated much discussion about how to preserve power to detect signals despite the detrimental effect of multiple testing on power. We develop a weighted multiple testing procedure that facilitates the…

Statistics Theory · Mathematics 2007-06-13 Kathryn Roeder , Bernie Devlin , Larry Wasserman

This paper introduces a statistical test inferring whether a variable allows separating two classes by means of a single critical value. Its test statistic is the prediction error of a nonparametric threshold classifier. While this approach…

Methodology · Statistics 2017-07-17 Fabian Schroeder

Statistically equivalent blocks are not frequently considered in the context of nonparametric two-sample hypothesis testing. Despite the limited exposure, this paper shows that a number of classical nonparametric hypothesis tests can be…

Methodology · Statistics 2025-06-11 Chase Holcombe

A two-sample hypothesis test is a statistical procedure used to determine whether the distributions generating two samples are identical. We consider the two-sample testing problem in a new scenario where the sample measurements (or sample…

Machine Learning · Computer Science 2024-07-01 Weizhi Li , Prad Kadambi , Pouria Saidi , Karthikeyan Natesan Ramamurthy , Gautam Dasarathy , Visar Berisha

Group testing, a problem with diverse applications across multiple disciplines, traditionally assumes independence across nodes' states. Recent research, however, focuses on real-world scenarios that often involve correlations among nodes,…

Information Theory · Computer Science 2025-04-02 Hesam Nikpey , Saswati Sarkar , Shirin Saeedi Bidokhti

Causal inference starts with a simple idea: compare groups that differ by treatment, not much else. Traditionally, similar groups are constructed using only observed covariates; however, it remains a long-standing challenge to incorporate…

Methodology · Statistics 2025-11-21 Ying Jin , José Zubizarreta

In this paper, we explore the modified Greenwood statistic, which, in contrast to the classical Greenwood statistic, is properly defined for random samples from any distribution. The classical Greenwood statistic, extensively examined in…

Statistics Theory · Mathematics 2024-05-21 Katarzyna Skowronek , Marek Arendarczyk , Radosław Zimroz , Agnieszka Wyłomańska

This paper clarifies a fundamental difference between causal inference and traditional statistical inference by formalizing a mathematical distinction between their respective parameters. We connect two major approaches to causal inference,…

Methodology · Statistics 2025-08-29 Muye Liu , Jun Xie

Classical tests for a difference in means control the type I error rate when the groups are defined a priori. However, when the groups are instead defined via clustering, then applying a classical test yields an extremely inflated type I…

Methodology · Statistics 2022-11-01 Lucy L. Gao , Jacob Bien , Daniela Witten

We consider a generalization of group testing where the potentially contaminated sets are the members of a given hypergraph ${\cal F}=(V,E)$. This generalization finds application in contexts where contaminations can be conditioned by some…

Data Structures and Algorithms · Computer Science 2023-11-28 Annalisa De Bonis
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