Related papers: Brain dynamics through spectral-structural neurona…
One important question in neuroscience is how global behavior in a brain network emerges from the interplay between network connectivity and the neural dynamics of individual nodes. To better understand this theoretical relationship, we…
Higher brain function relies upon the ability to flexibly integrate information across specialized communities of brain regions, however it is unclear how this mechanism manifests over time. In this study, we use time-resolved network…
How the information microscopically processed by individual neurons is integrated and used in organizing the behavior of an animal is a central question in neuroscience. The coherence of neuronal dynamics over different scales has been…
The ability to modulate brain states using targeted stimulation is increasingly being employed to treat neurological disorders and to enhance human performance. Despite the growing interest in brain stimulation as a form of neuromodulation,…
Objective While Alzheimer's disease (AD) and frontotemporal dementia (FTD) show some common memory deficits, these two disorders show partially overlapping complex spatiotemporal patterns of neural dynamics. The objective of this study is…
Diffusion Magnetic Resonance Imaging (MRI) exploits the anisotropic diffusion of water molecules in the brain to enable the estimation of the brain's anatomical fiber tracts at a relatively high resolution. In particular, tractographic…
Partial synchronization plays a crucial role in the functioning of neuronal networks: selective, coordinated activation of neurons enables information processing that flexibly adapts to a changing computational context. Since the structure…
To gain insight into the neural events responsible for visual perception of static and dynamic optical patterns, we study how neural activation spreads in arrays of inhibition-stabilized neural networks with nearest-neighbor coupling. The…
We introduce a foundational model for brain dynamics that utilizes stochastic optimal control (SOC) and amortized inference. Our method features a continuous-discrete state space model (SSM) that can robustly handle the intricate and noisy…
Neuronal circuits arise as axons and dendrites extend, navigate, and connect to target cells. Axonal growth, in particular, integrates deterministic guidance from substrate mechanics and geometry with stochastic fluctuations generated by…
How neural networks in the human brain represent commonsense knowledge, and complete related reasoning tasks is an important research topic in neuroscience, cognitive science, psychology, and artificial intelligence. Although the…
The brain produces rhythms in a variety of frequency bands. Some are likely by-products of neuronal processes; others are thought to be top-down. Produced entirely naturally, these rhythms have clearly recognizable beats, but they are very…
Hierarchically modular organization is a canonical network topology that is evolutionarily conserved in the nervous systems of animals. Within the network, neurons form directional connections defined by the growth of their axonal…
Cue integration, the combination of different sources of information to reduce uncertainty, is a fundamental computational principle of brain function. Starting from a normative model we show that the dynamics of multi-compartment neurons…
Despite the fact that the phenomenon of bursting activity is important for functioning of living neural networks, the mechanisms of its origin are still not clear. In this paper, we propose a new phenomenological model that can explain the…
The neural networks of the human brain act as very efficient parallel processing computers co-ordinating memory related responses to a multitude of input signals from sensory organs. Information storage, update and appropriate retrieval are…
Activity in coupled systems is often oscillatory, for example, the firing pattern of neuronal populations. Whereas these oscillations have been studied predominantly in local circuits, here we show how the topology of large-scale networks,…
Understanding how biological constraints shape neural computation is a central goal of computational neuroscience. Spatially embedded recurrent neural networks provide a promising avenue to study how modelled constraints shape the combined…
Understanding of short-term synaptic depression (STSD) and other forms of synaptic plasticity is a topical problem in neuroscience. Here we study the role of STSD in the formation of complex patterns of brain rhythms. We use a cortical…
In recent years, there have been many computational simulations of spontaneous neural dynamics. Here, we explore a model of spontaneous neural dynamics and allow it to control a virtual agent moving in a simple environment. This setup…