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Gene-environment (G$\times$E) interactions have important implications to elucidate the etiology of complex diseases beyond the main genetic and environmental effects. Outliers and data contamination in disease phenotypes of G$\times$E…

Methodology · Statistics 2020-06-11 Jie Ren , Fei Zhou , Xiaoxi Li , Shuangge Ma , Yu Jiang , Cen Wu

A new class of planar tessellations, named T-tessellations, was introduced in ([10]). A model was proposed to be considered as a completely random T-tessellation model (CRTT) and its Gibbsian variants were discussed. A general simulation…

Applications · Statistics 2020-08-03 Katarzyna Adamczyk-Chauvat , Mouna Kassa , Kiên Kiêu , Julien Papaïx , Radu S. Stoica

Networks underpin systems that range from finance to biology, yet their structure is often only partially observed. Current reconstruction methods typically fit the parameters of a model anew to each snapshot, thus offering no guidance to…

Physics and Society · Physics 2026-05-28 Mattia Marzi , Tiziano Squartini

We propose a method for detecting significant interactions in very large multivariate spatial point patterns. This methodology develops high dimensional data understanding in the point process setting. The method is based on modelling the…

Methodology · Statistics 2017-10-25 Tuomas Rajala , David Murrell , Sofia Olhede

Biclustering is used for simultaneous clustering of the observations and variables when there is no group structure known \textit{a priori}. It is being increasingly used in bioinformatics, text analytics, etc. Previously, biclustering has…

Methodology · Statistics 2020-09-14 Wangshu Tu , Sanjeena Subedi

In this article, we propose a novel spatial global-local spike-and-slab selection prior for image-on-scalar regression. We consider a Bayesian hierarchical Gaussian process model for image smoothing, that uses a flexible Inverse-Wishart…

Methodology · Statistics 2022-12-19 Zijian Zeng , Meng Li , Marina Vannucci

We propose a novel way of modelling time-varying networks, by inducing two-way sparsity on local models of node connectivity. This two-way sparsity separately promotes sparsity across time and sparsity across variables (within time).…

Methodology · Statistics 2020-11-19 Thomas E. Bartlett , Ioannis Kosmidis , Ricardo Silva

In collaborative forecast projects, the combining of multiple probabilistic forecasts into an ensemble is standard practice, with linear pooling being a common combination method. The weighting scheme of a linear pool should be tailored to…

Methodology · Statistics 2025-09-05 Spencer Wadsworth , Jarad Niemi

In the realm of statistical learning, the increasing volume of accessible data and increasing model complexity necessitate robust methodologies. This paper explores two branches of robust Bayesian methods in response to this trend. The…

Methodology · Statistics 2024-12-02 Masahiro Tanaka

Observations consisting of measurements on relationships for pairs of objects arise in many settings, such as protein interaction and gene regulatory networks, collections of author-recipient email, and social networks. Analyzing such data…

Methodology · Statistics 2010-02-22 Edoardo M Airoldi , David M Blei , Stephen E Fienberg , Eric P Xing

Gibbs-type priors are widely used as key components in several Bayesian nonparametric models. By virtue of their flexibility and mathematical tractability, they turn out to be predominant priors in species sampling problems, clustering and…

Methodology · Statistics 2021-08-30 Federico Camerlenghi , Riccardo Corradin , Andrea Ongaro

One of the fundamental tasks of science is to find explainable relationships between observed phenomena. One approach to this task that has received attention in recent years is based on probabilistic graphical modelling with sparsity…

Machine Learning · Statistics 2014-04-16 Peter Orchard , Felix Agakov , Amos Storkey

We consider the problem of sampling from a product-of-experts-type model that encompasses many standard prior and posterior distributions commonly found in Bayesian imaging. We show that this model can be easily lifted into a novel latent…

Image and Video Processing · Electrical Eng. & Systems 2026-04-16 Muhamed Kuric , Martin Zach , Andreas Habring , Michael Unser , Thomas Pock

Ising models are a simple generative approach to describing interacting binary variables. They have proven useful in a number of biological settings because they enable one to represent observed many-body correlations as the separable…

Machine Learning · Computer Science 2021-09-10 Emma Slade , Sonya Kiselgof , Lena Granovsky , Jeremy L. England

In the last years, tens of thousands gene expression profiles for cells of several organisms have been monitored. Gene expression is a complex transcriptional process where mRNA molecules are translated into proteins, which control most of…

Biomolecules · Quantitative Biology 2009-11-11 T. Ochiai , J. C. Nacher , T. Akutsu

We show how to construct a reduced description of interacting genes in noisy, small regulatory networks using coupled binary "spin" variables. Treating both the protein number and gene expression state variables stochastically and on equal…

Molecular Networks · Quantitative Biology 2015-05-13 Aleksandra M. Walczak , Peter G. Wolynes

The identification of disease-gene associations is instrumental in understanding the mechanisms of diseases and developing novel treatments. Besides identifying genes from RNA-Seq datasets, it is often necessary to identify gene clusters…

Genomics · Quantitative Biology 2025-11-14 Jake R. Patock , Rinki Ratnapriya , Arko Barman

We study the challenges of applying deep learning to gene expression data. We find experimentally that there exists non-linear signal in the data, however is it not discovered automatically given the noise and low numbers of samples used in…

Genomics · Quantitative Biology 2018-06-20 Francis Dutil , Joseph Paul Cohen , Martin Weiss , Georgy Derevyanko , Yoshua Bengio

Determining subgroups that respond especially well (or poorly) to specific interventions (medical or policy) requires new supervised learning methods tailored specifically for causal inference. Bayesian Causal Forest (BCF) is a recent…

Machine Learning · Statistics 2022-09-16 Nikolay Krantsevich , Jingyu He , P. Richard Hahn

We propose a posterior sampling algorithm for the problem of estimating multiple independent source signals from their noisy superposition. The proposed algorithm is a combination of Gibbs sampling method and plug-and-play (PnP) diffusion…

Signal Processing · Electrical Eng. & Systems 2025-09-17 Yi Zhang , Rui Guo , Yonina C. Eldar