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Protein similarity searches are a routine job for molecular biologists where a query sequence of amino acids needs to be compared and ranked against an ever-growing database of proteins. All available algorithms in this field can be grouped…
A lot of search approaches have been explored for the selection of features in pattern classification domain in order to discover significant subset of the features which produces better accuracy. In this paper, we introduced a Harmony…
This thesis presents two similarity-based approaches to sparse data problems. The first approach is to build soft, hierarchical clusters: soft, because each event belongs to each cluster with some probability; hierarchical, because cluster…
Supervised hashing aims to map the original features to compact binary codes that are able to preserve label based similarity in the Hamming space. Non-linear hash functions have demonstrated the advantage over linear ones due to their…
An increasing amount of trajectory data is being annotated with text descriptions to better capture the semantics associated with locations. The fusion of spatial locations and text descriptions in trajectories engenders a new type of…
Embedding image features into a binary Hamming space can improve both the speed and accuracy of large-scale query-by-example image retrieval systems. Supervised hashing aims to map the original features to compact binary codes in a manner…
As a key ingredient of the DBMS, index plays an important role in the query optimization and processing. However, it is a non-trivial task to apply existing indexes or design new indexes for new applications, where both data distribution…
Biclustering is a powerful unsupervised learning technique for simultaneously identifying coherent subsets of rows and columns in a data matrix, thus revealing local patterns that may not be apparent in global analyses. However, most…
Sequence alignment is common nowadays as it is used in many fields to determine how closely two sequences are related and at times to see how little they differ. In computational biology / Bioinformatics, there are many algorithms developed…
Annotation projection is an important area in NLP that can greatly contribute to creating language resources for low-resource languages. Word alignment plays a key role in this setting. However, most of the existing word alignment methods…
Databases are widespread, yet extracting relevant data can be difficult. Without substantial domain knowledge, multivariate search queries often return sparse or uninformative results. This paper introduces an approach for searching…
Cross-modal hashing is an important approach for multimodal data management and application. Existing unsupervised cross-modal hashing algorithms mainly rely on data features in pre-trained models to mine their similarity relationships.…
Various decision support systems are available that implement Data Mining and Data Warehousing techniques for diving into the sea of data for getting useful patterns of knowledge (pearls). Classification, regression, clustering, and many…
We apply the concept of subset seeds proposed in [1] to similarity search in protein sequences. The main question studied is the design of efficient seed alphabets to construct seeds with optimal sensitivity/selectivity trade-offs. We…
The alignment of protein-protein interaction (PPI) networks has many applications, such as the detection of conserved biological network motifs, the prediction of protein interactions, and the reconstruction of phylogenetic trees [1, 2, 3].…
Gene annotation has traditionally required direct comparison of DNA sequences between an unknown gene and a database of known ones using string comparison methods. However, these methods do not provide useful information when a gene does…
As the structural databases continue to expand, efficient methods are required to search similar structures of the query structure from the database. There are many previous works about comparing protein 3D structures and scanning the…
Sparse Bayesian learning (SBL) has been extensively utilized in data-driven modeling to combat the issue of overfitting. While SBL excels in linear-in-parameter models, its direct applicability is limited in models where observations…
With the dramatic increase in the amount of the text-based data which commonly contains misspellings and other errors, querying such data with flexible search patterns becomes more and more commonplace. Relational databases support the LIKE…
Semantic matching of natural language sentences or identifying the relationship between two sentences is a core research problem underlying many natural language tasks. Depending on whether training data is available, prior research has…