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In allosteric proteins, binding a ligand can affect function at a distant location, for example by changing the binding affinity of a substrate at the active site. The induced fit and population shift models, which differ by the assumed…

Biological Physics · Physics 2019-10-28 Riccardo Ravasio , Solange Flatt , Le Yan , Stefano Zamuner , Carolina Brito , Matthieu Wyart

We show that certain non-linear dynamical systems with non-linearities in the form of Hill functions, can be approximated by piecewise linear dynamical systems. The resulting piecewise systems have closed form solutions that can be used to…

Molecular Networks · Quantitative Biology 2012-01-11 Ajit Kumar , Krešimir Josić

When particles interact via two-body short-range central potential wells, binding can occur for some critical values of the coupling constants. Using the envelope theory, upper bounds for critical coupling constants are computed for quantum…

Quantum Physics · Physics 2025-06-13 Clara Tourbez , Claude Semay , Cyrille Chevalier

Single receptor-ligand bonds have finite lifetimes, so that biological systems can dynamically react to changes in their environment. In cell adhesion, adhesion bonds usually act cooperatively in adhesion clusters. Outside the cellular…

Soft Condensed Matter · Physics 2007-05-23 T. Erdmann , U. S. Schwarz

Binding energies of light, $A\leq 6$, $\Lambda\Lambda$ hypernuclei are calculated using the stochastic variational method in a pionless effective field theory (EFT) approach at leading order with the purpose of assessing critically the…

Nuclear Theory · Physics 2020-12-22 L. Contessi , M. Schäfer , N. Barnea , A. Gal , J. Mareš

Phosphorelays are a class of signaling mechanisms used by cells to respond to changes in their environment. Phosphorelays (of which two-component systems constitute a special case) are particularly abundant in prokaryotes and have been…

Molecular Networks · Quantitative Biology 2011-09-26 Michael Knudsen , Elisenda Feliu , Carsten Wiuf

Despite recent advances and focus on rigorous uncertainty quantification for microscopic models of quantum many-body systems, the uncertainty on the dynamics of those systems has been under-explored. To address this, we have used…

Nuclear Theory · Physics 2022-11-30 K. Godbey , A. S. Umar , C. Simenel

Against common sense, auxetic materials expand or contract perpendicularly when stretched or compressed, respectively, by uniaxial strain, being characterized by a negative Poisson's ratio $\nu$. The amount of deformation in response to the…

Soft Condensed Matter · Physics 2022-02-22 Andrea Ninarello , José Ruiz-Franco , Emanuela Zaccarelli

Multistationarity in biological systems is a mechanism of cellular decision making. In particular, signaling pathways regulated by protein phosphorylation display features that facilitate a variety of responses to different biological…

Subcellular Processes · Quantitative Biology 2011-07-05 Elisenda Feliu , Carsten Wiuf

We develop a linear response theory to provide a unified description of two recent spectroscopy protocols for probing one-dimensional supersolid states realized in cold-atom systems. Both protocols involve applying a periodic optical…

Quantum Gases · Physics 2025-05-09 L. M. Platt , D. Baillie , P. B. Blakie

Correlations and other collective phenomena in a schematic model of heterogeneous binary agents (individual spin-glass samples) are considered on the complete graph and also on 2d and 3d regular lattices. The system's stochastic dynamics is…

Disordered Systems and Neural Networks · Physics 2014-02-25 Imre Kondor , István Csabai , Gábor Papp , Enys Mones , Gábor Czimbalmos , Máté Csaba Sándor

We study experimentally accessible lower bounds on entanglement measures based on entropic uncertainty relations. Experimentally quantifying entanglement is highly desired for applications of quantum simulation experiments to fundamental…

Quantum Physics · Physics 2021-05-25 Bjarne Bergh , Martin Gärttner

A stochastic model for the dynamics of enzymatic catalysis in explicit, effective solvents under physiological conditions is presented. Analytically-computed first passage time densities of a diffusing particle in a spherical shell with…

Biomolecules · Quantitative Biology 2015-06-04 Jeremy Schofield , Paul Inder , Raymond Kapral

We perform precision measurements on a Mott-insulator quantum state of ultracold atoms with tunable interactions. We probe the dependence of the superfluid-to-Mott-insulator transition on the interaction strength and explore the limits of…

Quantum Physics · Physics 2011-11-23 M. J. Mark , E. Haller , K. Lauber , J. G. Danzl , A. J. Daley , H. -C. Nägerl

Virtual excitations, inherent to ultrastrongly coupled light-matter systems, induce measurable modifications in system properties, offering a novel resource for quantum technologies. In this work, we demonstrate how these virtual…

Quantum Physics · Physics 2025-09-12 Christoph Hotter , Adam Miranowicz , Karol Gietka

Turing instabilities of reaction-diffusion systems can only arise if the diffusivities of the chemical species are sufficiently different. This threshold is unphysical in most systems with $N=2$ diffusing species, forcing experimental…

Soft Condensed Matter · Physics 2026-03-17 Pierre A. Haas , Raymond E. Goldstein

Quantum phase transitions are often embodied by the critical behavior of purely quantum quantities such as entanglement or quantum fluctuations. In critical regions, we underline a general scaling relation between the entanglement entropy…

Quantum Physics · Physics 2012-10-08 Pierre Nataf , Mehmet Dogan , Karyn Le Hur

Reaction-diffusion processes are the foundational model for a diverse range of complex systems, ranging from biochemical reactions to social agent-based phenomena. The underlying dynamics of these systems occur at the individual…

Statistical Mechanics · Physics 2025-10-15 Mauricio J. del Razo , Margarita Kostré

We present an extension of the Poisson-Boltzmann model in which the solute of interest is immersed in an assembly of self-orienting Langevin water dipoles, anions, cations, and hydrophobic molecules, all of variable densities. Interactions…

Biological Physics · Physics 2021-04-08 Patrice Koehl , Marc Delarue , Henri Orland

Mass-action chemical reaction systems are frequently used in Computational Biology. The corresponding polynomial dynamical systems are often large (consisting of tens or even hundreds of ordinary differential equations) and poorly…

Dynamical Systems · Mathematics 2011-07-13 Mercedes Perez Millan , Alicia Dickenstein , Anne Shiu , Carsten Conradi
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