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Related papers: Toward Biochemical Probabilistic Computation

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Probabilistic inference provides a language for describing how organisms may learn from and adapt to their environment. The computations needed to implement probabilistic inference often require specific representations, akin to having the…

Molecular Networks · Quantitative Biology 2018-06-28 Yarden Katz , Michael Springer , Walter Fontana

Bayesian models of cognition hypothesize that human brains make sense of data by representing probability distributions and applying Bayes' rule to find the best explanation for available data. Understanding the neural mechanisms underlying…

Neural and Evolutionary Computing · Computer Science 2021-07-02 Milad Kharratzadeh , Thomas R. Shultz

Despite recent molecular technique improvements, biological knowledge remains incomplete. Reasoning on living systems hence implies to integrate heterogeneous and partial informations. Although current investigations successfully focus on…

Quantitative Methods · Quantitative Biology 2009-09-29 Jérémie Bourdon , Damien Eveillard , Samuel Gabillard , Theo Merle

Despite widespread success in language understanding and generation, large language models (LLMs) exhibit unclear and often inconsistent behavior when faced with tasks that require probabilistic reasoning. In this work, we present the first…

Computation and Language · Computer Science 2025-09-29 Mobina Pournemat , Keivan Rezaei , Gaurang Sriramanan , Arman Zarei , Jiaxiang Fu , Yang Wang , Hamid Eghbalzadeh , Soheil Feizi

When collaborating with an AI system, we need to assess when to trust its recommendations. If we mistakenly trust it in regions where it is likely to err, catastrophic failures may occur, hence the need for Bayesian approaches for…

Artificial Intelligence · Computer Science 2021-02-23 Federico Cerutti , Lance M. Kaplan , Angelika Kimmig , Murat Sensoy

Large language models (LLMs) are increasingly used as agents that interact with users and with the world. To do so successfully, LLMs must construct representations of the world and form probabilistic beliefs about them. To provide…

Computation and Language · Computer Science 2026-01-16 Linlu Qiu , Fei Sha , Kelsey Allen , Yoon Kim , Tal Linzen , Sjoerd van Steenkiste

Cells regulate themselves via dizzyingly complex biochemical processes called signaling pathways. These are usually depicted as a network, where nodes represent proteins and edges indicate their influence on each other. In order to…

Molecular Networks · Quantitative Biology 2021-01-13 David Merrell , Anthony Gitter

A framework is presented for a computational theory of probabilistic argument. The Probabilistic Reasoning Environment encodes knowledge at three levels. At the deepest level are a set of schemata encoding the system's domain knowledge.…

Artificial Intelligence · Computer Science 2013-04-05 Kathryn Blackmond Laskey

In recent years, research unveiled more and more evidence for the so-called Bayesian Brain Paradigm, i.e. the human brain is interpreted as a probabilistic inference machine and Bayesian modelling approaches are hence used successfully. One…

Neural and Evolutionary Computing · Computer Science 2019-04-30 Kevin Jasberg , Sergej Sizov

Bayesian networks provide a probabilistic semantics for qualitative assertions about likelihood. A qualitative reasoner based on an algebra over these assertions can derive further conclusions about the influence of actions. While the…

Artificial Intelligence · Computer Science 2013-04-12 Michael P. Wellman

It is widely believed that the brain performs approximate probabilistic inference to estimate causal variables in the world from ambiguous sensory data. To understand these computations, we need to analyze how information is represented and…

Neurons and Cognition · Quantitative Biology 2017-05-16 Xaq Pitkow , Dora Angelaki

Current theories of perception suggest that the brain represents features of the world as probability distributions, but can such uncertain foundations provide the basis for everyday vision? Perceiving objects and scenes requires knowing…

Neurons and Cognition · Quantitative Biology 2022-11-30 Andrey Chetverikov , Árni Kristjánsson

Comprehensible explanations of probabilistic reasoning are a prerequisite for wider acceptance of Bayesian methods in expert systems and decision support systems. A study of human reasoning under uncertainty suggests two different…

Artificial Intelligence · Computer Science 2013-04-05 Max Henrion , Marek J. Druzdzel

The idea that the brain is a probabilistic (Bayesian) inference machine, continuously trying to figure out the hidden causes of its inputs, has become very influential in cognitive (neuro)science over recent decades. Here I present a…

Neurons and Cognition · Quantitative Biology 2024-02-15 Eelke Spaak

The human brain copes with sensory uncertainty in accordance with Bayes' rule. However, it is unknown how the brain makes predictions in the presence of parameter uncertainty. Here, we tested whether and how humans take parameter…

Neurons and Cognition · Quantitative Biology 2020-07-01 Jannes Jegminat , Maya Jastrzebowska , Matt Pachai , Michael Herzog , Jean-Pascal Pfister

The Bayesian approach to data analysis provides a powerful way to handle uncertainty in all observations, model parameters, and model structure using probability theory. Probabilistic programming languages make it easier to specify and fit…

Bayesian interpretations of neural processing require that biological mechanisms represent and operate upon probability distributions in accordance with Bayes' theorem. Many have speculated that synaptic failure constitutes a mechanism of…

Neurons and Cognition · Quantitative Biology 2022-10-05 Kevin McKee , Ian Crandell , Rishidev Chaudhuri , Randall O'Reilly

Bayesian network is a complete model for the variables and their relationships, it can be used to answer probabilistic queries about them. A Bayesian network can thus be considered a mechanism for automatically applying Bayes' theorem to…

Artificial Intelligence · Computer Science 2010-11-08 Jianguo Ding

Humans and other animals behave as if we perform fast Bayesian inference underlying decisions and movement control given uncertain sense data. Here we show that a biophysically realistic model of the subthreshold membrane potential of a…

Neurons and Cognition · Quantitative Biology 2014-06-20 Michael G. Paulin , Andre van Schaik

Reasoning is key to many decision making processes. It requires consolidating a set of rule-like premises that are often associated with degrees of uncertainty and observations to draw conclusions. In this work, we address both the case…

Computation and Language · Computer Science 2024-10-15 Timo Pierre Schrader , Lukas Lange , Simon Razniewski , Annemarie Friedrich
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