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Cellular self-assembly and organization are fundamental steps for the development of biological tissues. In this paper, within the framework of a cellular automata model, we address how an ordered tissue pattern spontaneously emerges from a…

Biological Physics · Physics 2019-10-24 Debangana Mukhopadhyay , Rumi De

Soft-granular media, such as dense emulsions, foams or tissues, exhibit either fluid- or solid-like properties depending on the applied external stresses. Whereas bulk rheology of such materials has been thoroughly investigated, the…

Soft Condensed Matter · Physics 2024-07-04 Michal Bogdan , Jesus Pineda , Mihir Durve , Leon Jurkiewicz , Sauro Succi , Giovanni Volpe , Jan Guzowski

We show that the process of spontaneous symmetry breaking can trap a field theoretic system in a highly non-trivial state containing a lattice of domain walls. In one large compact space dimension, a lattice is inevitably formed. In two…

High Energy Physics - Phenomenology · Physics 2009-11-10 Nuno D. Antunes , Tanmay Vachaspati

Robust self-organization of subcellular structures is a key principle governing the dynamics and evolution of cellular life. In fission yeast cells undergoing division, the mitotic spindle spontaneously emerges from the interaction of…

Soft Condensed Matter · Physics 2024-06-03 David A. Head , W. J. Briels , Gerhard Gompper

In this work we propose a generalization of Winfree's abstract Tile Assembly Model (aTAM) in which tile types are assigned rigid shapes, or geometries, along each tile face. We examine the number of distinct tile types needed to assemble…

Computational Geometry · Computer Science 2015-03-19 Bin Fu , Matthew J. Patitz , Robert T. Schweller , Bobby Sheline

We introduce a lattice model to probe the effect of active self-disassembly on equilibrium self-assembly. Surprisingly, we find conditions under which active self-disassembly enhances the yield of a target structure above that achieved by…

Soft Condensed Matter · Physics 2024-05-14 Karsten Kruse , Jean-Pierre Eckmann , Wilson C. K. Poon

In the abstract Tile Assembly Model (aTAM) square tiles self-assemble, autonomously binding via glues on their edges, to form structures. Algorithmic aTAM systems can be designed in which the patterns of tile attachments are forced to…

Emerging Technologies · Computer Science 2022-11-10 Andrew Alseth , Matthew J. Patitz

Self-assembly of proteins into amyloid aggregates is an important biological phenomenon associated with human diseases such as Alzheimer's disease. Amyloid fibrils also have potential applications in nano-engineering of biomaterials. The…

Cell Behavior · Quantitative Biology 2016-05-25 Sarah Eugene , Wei-Feng Xue , Philippe Robert , Marie Doumic-Jauffret

Within biology, it is of interest to construct DNA complexes of a certain shape. These complexes can be represented through graph theory, using edges to model strands of DNA joined at junctions, represented by vertices. Because guided…

Investigation of protein self-assembly processes is important for the understanding of the growth processes of functional proteins as well as disease-causing amyloids. Inside cells, intrinsic molecular fluctuations are so high that they…

Biological Physics · Physics 2021-02-03 John Bridstrup , John S Schreck , Jesse L Jorgenson , Jian-Min Yuan

The experimental use of micropatterned quasi-1D substrates has emerged as an useful experimental tool to study the nature of cell-cell interactions and gain insight on collective behaviour of cell colonies. Inspired by these experiments, we…

Soft Condensed Matter · Physics 2025-07-31 Harshal Potdar , Ignacio Pagonabarraga , Sudipto Muhuri

The Tile Automata (TA) model describes self-assembly systems in which monomers can build structures and transition with an adjacent monomer to change their states. This paper shows that seeded TA is a non-committal intrinsically universal…

Cellular Automata and Lattice Gases · Physics 2024-07-17 Tim Gomez , Elise Grizzell , Asher Haun , Ryan Knobel , Tom Peters , Robert Schweller , Tim Wylie

In this paper we prove that if two self-similar tiling systems, with respective stretching factors $\lambda_1$ and $\lambda_2$, have a common factor which is a non periodic tiling system, then $\lambda_1$ and $\lambda_2$ are…

Dynamical Systems · Mathematics 2007-12-31 Maria Isabel Cortez , Fabien Durand

A fundamental characteristic of matter is its ability to form ordered structures under the right thermodynamic conditions. Predicting these structures - and their properties - from the attributes of a material's building blocks is the holy…

Soft Condensed Matter · Physics 2012-02-13 Pablo F. Damasceno , Michael Engel , Sharon C. Glotzer

Anisotropy at the level of the inter-particle interaction provides the particles with specific instructions for the self-assembly of target structures. The ability to synthesize non-spherical colloids, together with the possibility of…

Soft Condensed Matter · Physics 2020-01-03 Carina Karner , Christoph Dellago , Emanuela Bianchi

Steady structures originating from dynamic self-assembly have begun to show their advantages in new generation materials, and pose challenges to equilibrium self-assembly. In view of the important role of confinement in self-assembly, here,…

Computational Physics · Physics 2019-08-06 Rui-fen Zhang , Chun-lai Ren , Jia-wei Feng , Yu-qiang Ma

The ability to control forces between sub-micron-scale building blocks offers considerable potential for designing new materials through self-assembly. A typical paradigm is to first identify a particular (crystal) structure that has some…

Soft Condensed Matter · Physics 2024-04-24 Mengjie Zu , Carl Goodrich

We consider a model of algorithmic self-assembly of geometric shapes out of square Wang tiles studied in SODA 2010, in which there are two types of tiles (e.g., constructed out of DNA and RNA material) and one operation that destroys all…

Computational Complexity · Computer Science 2010-07-09 Erik D. Demaine , Matthew J. Patitz , Robert T. Schweller , Scott M. Summers

We investigate the iterative construction of discrete Laplacians on 2D square lattices, revealing emergent fractal-like patterns shaped by modular arithmetic. While classical 2222-style iterations reproduce known structures such as the…

Dynamical Systems · Mathematics 2026-03-16 Małgorzata Nowak-Kępczyk

Structural hierarchy, in which materials possess distinct features on multiple length scales, is ubiquitous in nature; diverse biological materials, such as bone, cellulose, and muscle, have as many as ten hierarchical levels. Structural…

Soft Condensed Matter · Physics 2019-06-19 Jonathan Michel , Peter Yunker