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The adhesion of cells is mediated by membrane receptors that bind to complementary ligands in apposing cell membranes. It is generally assumed that the lateral diffusion of mobile receptor-ligand bonds in membrane-membrane adhesion zones is…

Soft Condensed Matter · Physics 2007-05-23 H. Krobath , G. J. Schuetz , R. Lipowsky , T. R. Weikl

Shape transformations of flat bilayer membranes and vesicles induced by hydrolysis and condensation reactions of amphiphilic molecules are studied using coarse-grained molecular dynamics simulations. The hydrolysis and condensation…

Soft Condensed Matter · Physics 2018-01-31 Koh M. Nakagawa , Hiroshi Noguchi

Motivated by the experimental study of Tayebi et al. [Nature Mater. 11, 1074 (2012)] on phase separation of stacked multi-component lipid bilayers, we propose a model composed of stacked two-dimensional Ising spins. We study both its static…

Soft Condensed Matter · Physics 2015-12-14 T. Hoshino , S. Komura , D. Andelman

We analyze the displacements of the particles of a glass-forming molecular liquid perpendicular to a confining solid surface, using extensive molecular dynamics simulations with atomistic models. In the vicinity of an attractive surface,…

Soft Condensed Matter · Physics 2024-10-15 Alireza F. Behbahani , Vagelis Harmandaris

The dynamics of glass-forming liquids display several outstanding features, such as two-step relaxation and dynamic heterogeneities, which are difficult to predict quantitatively from first principles. In this work, we revisit a simple…

Statistical Mechanics · Physics 2022-11-23 Daniele Coslovich , Atsushi Ikeda

Liquid water is not only of obvious importance but also extremely intriguing, displaying many anomalies that still challenge our understanding of such an a priori simple system. The same is true when looking at nanoconfined water: The…

Soft Condensed Matter · Physics 2016-06-29 Jon Zubeltzu , Fabiano Corsetti , M. V. Fernandez-Serra , Emilio Artacho

We devise a soft, solvent-free, coarse-grained model for lipid bilayer membranes. The non-bonded interactions take the form of a weighted-density functional which allows us to describe the thermodynamics of self-assembly and packing effects…

Soft Condensed Matter · Physics 2010-06-09 Martin Hömberg , Marcus Müller

A hydrated 1,2-dimyristoyl-sn-glycero-3-phosphorylcholine (DMPC) lipid membrane is investigated using an all atom molecular dynamics simulation at 308K to find out the physical sources of universal slow relaxation of hydration layers.…

Soft Condensed Matter · Physics 2018-08-14 Abhinav Srivastava , Smarajit Karmakar , Ananya Debnath

We study a continuum model of the lipid bilayer based on minimizing the free energy of a mixture of water and lipid molecules. This paper extends previous work by Blom & Peletier (2004) in the following ways. (a) It formulates a more…

Soft Condensed Matter · Physics 2020-06-05 Phillip L. Wilson , Huaxiong Huang , Shu Takagi

The biological function of membranes is closely related to their softness, which is often studied through the membranes' thermally-driven fluctuations. The analysis commonly assumes that the relaxation rate of a pure bending deformation is…

Soft Condensed Matter · Physics 2024-07-09 Hammad A. Faizi , Rony Granek , Petia M. Vlahovska

In this paper we present the results of a large-scale numerical investigation of structural properties of a model of cell membrane, simulated as a bilayer of flexible molecules in vacuum. The study was performed by carrying out extensive…

Biological Physics · Physics 2009-11-07 G. La Penna , S. Letardi , V. Minicozzi , S. Morante , G. C. Rossi , G. Salina

We study a dynamical curvature instability caused by a local chemical modification of a phospholipid membrane. In our experiments, a basic solution is microinjected close to a giant unilamellar vesicle, which induces a local chemical…

Soft Condensed Matter · Physics 2015-03-19 Anne-Florence Bitbol , Jean-Baptiste Fournier , Miglena I. Angelova , Nicolas Puff

In this paper we introduce a novel method to simulate lateral diffusion of inclusions in a fluctuating membrane. The regarded systems are governed by two dynamic processes: the height fluctuations of the membrane and the diffusion of the…

Soft Condensed Matter · Physics 2007-05-23 Ellen Reister-Gottfried , Stefan M. Leitenberger , Udo Seifert

In this article, we briefly review the studies on magnetic relaxation behaviours. The theoretical as well as experimental investigations are reported briefly. A major part of this article is devoted to the recent Monte Carlo investigations…

Statistical Mechanics · Physics 2023-11-21 Ishita Tikader , Muktish Acharyya

Membrane tension is an acknowledged regulator of a wide array of cell functions; however, whether it acts locally or globally in different contexts remains debated. Recent experiments that locally perturb tension and measure the response…

Soft Condensed Matter · Physics 2025-02-11 Emeline Laborie , Andrew Callan-Jones

An analytical theory is developed to describe the dynamics of a closed lipid bilayer membrane (vesicle) freely suspended in a general linear flow. Considering a nearly spherical shape, the solution to the creeping-flow equations is obtained…

Biological Physics · Physics 2009-11-13 Petia M. Vlahovska , Ruben Serral Gracia

The red blood cell (RBC) membrane is composed of a lipid bilayer and a cytoskeleton interconnected by protein junction complexes, allowing for potential sliding between the lipid bilayer and the cytoskeleton. Despite this biological…

Fluid Dynamics · Physics 2024-01-23 V. Puthumana , P. G. Chen , M. Leonetti , R. Lasserre , M. Jaeger

Using numerical simulations, we characterized the behavior of an elastic membrane immersed in an active fluid. Our findings reveal a nontrivial folding and re-expansion of the membrane that is controlled by the interplay of its resistance…

Soft Condensed Matter · Physics 2015-07-24 S. A. Mallory , C. Valeriani , A. Cacciuto

The influence of an external flow on the relaxation dynamics of a single polymer is investigated theoretically and numerically. We show that a pronounced dynamical slowdown occurs in the vicinity of the coil-stretch transition, especially…

Chaotic Dynamics · Physics 2007-05-23 Antonio Celani , Alberto Puliafito , Dario Vincenzi

Stress relaxation following deformation of an entangled polymeric liquid is thought to be affected by transient reforming of chain entanglements. In this work, we use single molecule techniques to study the relaxation of individual polymers…

Soft Condensed Matter · Physics 2018-07-04 Yuecheng Zhou , Charles M. Schroeder