English
Related papers

Related papers: Burrows-Wheeler transform for terabases

200 papers

Motivation The Burrows-Wheeler transform (BWT) is the foundation of many algorithms for compression and indexing of text data, but the cost of computing the BWT of very large string collections has prevented these techniques from being…

Data Structures and Algorithms · Computer Science 2015-03-20 Anthony J. Cox , Markus J. Bauer , Tobias Jakobi , Giovanna Rosone

Popular sequence alignment tools such as BWA convert a reference genome to an indexing data structure based on the Burrows-Wheeler Transform (BWT), from which matches to individual query sequences can be rapidly determined. However the…

Genomics · Quantitative Biology 2013-04-23 Anthony J. Cox , Tobias Jakobi , Giovanna Rosone , Ole B. Schulz-Trieglaff

Motivation: Burrows-Wheeler Transform (BWT) is a common component in full-text indices. Initially developed for data compression, it is particularly powerful for encoding redundant sequences such as pangenome data. However, BWT construction…

Genomics · Quantitative Biology 2025-09-10 Heng Li

The Burrows-Wheeler Transform (BWT) is an efficient invertible text transformation algorithm with the properties of tending to group identical characters together in a run, and enabling search of the text. This transformation has extensive…

Human-Computer Interaction · Computer Science 2024-02-28 Lily Major , Dave Davies , Amanda Clare , Jacqueline W. Daykin , Benjamin Mora , Christine Zarges

The Burrows-Wheeler transform (BWT) is integral to the FM-index, which is used extensively in text compression, indexing, pattern search, and bioinformatic problems as de novo assembly and read alignment. Thus, efficient construction of the…

Data Structures and Algorithms · Computer Science 2025-02-04 Enno Adler , Stefan Böttcher , Rita Hartel , Cederic Alexander Steininger

The Burrows-Wheeler Transform (BWT) serves as the basis for many important sequence indexes. On very large datasets (e.g. genomic databases), classical BWT construction algorithms are often infeasible because they usually need to have the…

Data Structures and Algorithms · Computer Science 2025-09-24 Jannik Olbrich

The Burrows-Wheeler transform (BWT) is a well studied text transformation widely used in data compression and text indexing. The BWT of two strings can also provide similarity measures between them, based on the observation that the more…

Data Structures and Algorithms · Computer Science 2020-09-10 Felipe A. Louza , Guilherme P. Telles , Simon Gog , Liang Zhao

The Burrows-Wheeler-Transform (BWT) is an invertible permutation of a text known to be highly compressible but also useful for sequence analysis, what makes the BWT highly attractive for lossless data compression. In this paper, we present…

Data Structures and Algorithms · Computer Science 2018-04-06 Uwe Baier

Due to the exponential growth of genomic data, constructing dedicated data structures has become the principal bottleneck in common bioinformatics applications. In particular, the Burrows-Wheeler Transform (BWT) is the basis of some of the…

Data Structures and Algorithms · Computer Science 2023-05-15 Francesco Masillo

We present a new semi-external algorithm that builds the Burrows--Wheeler transform variant of Bauer et al. (a.k.a., BCR BWT) in linear expected time. Our method uses compression techniques to reduce computational costs when the input is…

Data Structures and Algorithms · Computer Science 2023-08-15 Diego Díaz-Domínguez , Gonzalo Navarro

In this paper we propose a flexible and lightweight technique for merging compressed indices based on variants of Burrows-Wheeler transform (BWT), thus addressing the need for algorithms that compute compressed indices over large…

Data Structures and Algorithms · Computer Science 2019-03-06 Lavinia Egidi , Giovanni Manzini

When building Burrows-Wheeler Transforms (BWTs) of truly huge datasets, prefix-free parsing (PFP) can use an unreasonable amount of memory. In this paper we show how if a dataset can be broken down into small datasets that are not very…

Data Structures and Algorithms · Computer Science 2025-06-09 Diego Diaz-Dominguez , Travis Gagie , Veronica Guerrini , Ben Langmead , Zsuzsanna Liptak , Giovanni Manzini , Francesco Masillo , Vikram Shivakumar

The Burrows-Wheeler Transform (BWT) is a string transformation technique widely used in areas such as bioinformatics and file compression. Many applications combine a run-length encoding (RLE) with the BWT in a way which preserves the…

Discrete Mathematics · Computer Science 2025-09-18 Lily Major , Amanda Clare , Jacqueline W. Daykin , Benjamin Mora , Christine Zarges

The Burrows-Wheeler Transform (BWT) is among the most influential discoveries in text compression and DNA storage. It is a reversible preprocessing step that rearranges an $n$-letter string into runs of identical characters (by exploiting…

Data Structures and Algorithms · Computer Science 2018-12-06 Sandip Sinha , Omri Weinstein

Introduced about thirty years ago in the field of Data Compression, the Burrows-Wheeler Transform (BWT) is a string transformation that, besides being a booster of the performance of memoryless compressors, plays a fundamental role in the…

Data Structures and Algorithms · Computer Science 2023-05-09 Raffaele Giancarlo , Giovanni Manzini , Antonio Restivo , Giovanna Rosone , Marinella Sciortino

The Burrows-Wheeler Transform (BWT) is a word transformation introduced in 1994 for Data Compression. It has become a fundamental tool for designing self-indexing data structures, with important applications in several area in science and…

Data Structures and Algorithms · Computer Science 2019-07-05 Raffaele Giancarlo , Giovanni Manzini , Antonio Restivo , Giovanna Rosone , Marinella Sciortino

Advances in DNA sequencing technology have stimulated the development of algorithms and tools for processing very large collections of short strings (reads). Short-read alignment and assembly are among the most well-studied problems. Many…

Genomics · Quantitative Biology 2014-01-30 Chi-Man Liu , Ruibang Luo , Tak-Wah Lam

The Burrows-Wheeler Transform (BWT) is an invertible text transformation that permutes symbols of a text according to the lexicographical order of its suffixes. BWT is the main component of popular lossless compression programs (such as…

Data Structures and Algorithms · Computer Science 2021-04-13 Dominik Kempa , Tomasz Kociumaka

Burrows-Wheeler transform (BWT) is an invertible text transformation that, given a text $T$ of length $n$, permutes its symbols according to the lexicographic order of suffixes of $T$. BWT is one of the most heavily studied algorithms in…

Data Structures and Algorithms · Computer Science 2020-12-09 Dominik Kempa , Tomasz Kociumaka

In recent years, the focus of bioinformatics research has moved from individual sequences to collections of sequences. Given the fundamental role of the Burrows-Wheeler Transform (BWT) in string processing, a number of dedicated tools have…

Data Structures and Algorithms · Computer Science 2025-05-28 Davide Cenzato , Zsuzsanna Lipták
‹ Prev 1 2 3 10 Next ›