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The ability of a cell to communicate with its environment is essential for key cellular functions like replication, metabolism, or cell fate decisions. The involved molecular mechanisms are highly dynamic and difficult to capture…

Human-Computer Interaction · Computer Science 2025-09-11 Lena Cibulski , Fiete Haack , Adelinde Uhrmacher , Stefan Bruckner

The performance of molecular communication is significantly impacted by the reception process of the messenger molecules. The receptors' size and density, however, have yet to be investigated. In this letter, we analyze the effect of…

Emerging Technologies · Computer Science 2014-11-26 Ali Akkaya , H. Birkan Yilmaz , Chan-Byoung Chae , Tuna Tugcu

Metastasis is a process of cell migration that can be collective and guided by chemical cues. Viewing metastasis in this way, as a physical phenomenon, allows one to draw upon insights from other studies of collective sensing and migration…

Biological Physics · Physics 2016-03-10 Julien Varennes , Andrew Mugler

Genetic regulatory networks enable cells to respond to the changes in internal and external conditions by dynamically coordinating their gene expression profiles. Our ability to make quantitative measurements in these biochemical circuits…

Biological Physics · Physics 2015-03-17 Aleksandra M Walczak , Gašper Tkačik

Central to the functioning of a living cell is its ability to control the readout or expression of information encoded in the genome. In many cases, a single transcription factor protein activates or represses the expression of many genes.…

Molecular Networks · Quantitative Biology 2013-05-29 Aleksandra M. Walczak , Gapser Tkacik , William Bialek

Eukaryotic cells perform chemotaxis by determining the direction of chemical gradients based on stochastic sensing of concentrations at the cell surface. To examine the efficiency of this process, previous studies have investigated the…

Cell Behavior · Quantitative Biology 2025-02-06 Kento Nakamura , Tetsuya J. Kobayashi

Large MIMO transceivers are integral components of next-generation wireless networks. However, for such systems to be practical, their channel estimation process needs to be fast and reliable. Although several solutions for fast estimation…

Information Theory · Computer Science 2021-01-20 Yahia Shabara , C. Emre Koksal , Eylem Ekici

Specific interactions between receptors and their target ligands in the presence of non-target ligands are crucial for biological processes such as T cell ligand discrimination. To discriminate between the target and non-target ligands,…

Molecular Networks · Quantitative Biology 2017-07-19 Masashi K. Kajita , Kazuyuki Aihara , Tetsuya J. Kobayashi

Sensing is the process of deriving signals from the environment that allows artificial systems to interact with the physical world. The Shannon theorem specifies the maximum rate at which information can be acquired. However, this upper…

Neural and Evolutionary Computing · Computer Science 2018-02-16 Anh Tuan Nguyen , Jian Xu , Zhi Yang

We derive and discuss general physical bounds on the electromagnetic scattering and absorption of passive structures. Our theory, based on passivity and power conservation, quantifies the minimum and maximum allowed scattering for an object…

Optics · Physics 2015-06-17 Romain Fleury , Jason Soric , Andrea Alu

Cellular automata are one-dimensional arrays of interconnected interacting finite automata. We investigate one of the weakest classes, the real-time one-way cellular automata, and impose an additional restriction on their inter-cell…

Formal Languages and Automata Theory · Computer Science 2009-07-30 Martin Kutrib , Andreas Malcher

This paper considers the problem of channel sensing in cognitive radios. The system model considered is a set of N parallel (dis-similar) channels, where each channel at any given time is either available or occupied by a legitimate user.…

Information Theory · Computer Science 2009-10-12 G. Chung , S. Vishwanath , C. S. Hwang

The manner in which signals propagate through dense granular systems in both space and time is not well understood. In order to learn more about this process, we carry out discrete element simulations of the system response to excitations…

Soft Condensed Matter · Physics 2008-05-15 L. Kondic , O. M. Dybenko , R. P. Behringer

To recognize pathogens, B and T lymphocytes are endowed with a wide repertoire of receptors generated stochastically by V(D)J recombination. Measuring and estimating the diversity of these receptors is of great importance for understanding…

Populations and Evolution · Quantitative Biology 2020-11-20 Thierry Mora , Aleksandra Walczak

Metasurface with bound states in the continuum (BICs) offer exceptional potential for optical sensing due to their inherently high quality (Q) factors. However, the detection of symmetry-protected BICs remains experimentally challenging due…

With the completion of human genome mapping, the focus of scientists seeking to explain the biological complexity of living systems is shifting from analyzing the individual components (such as a particular gene or biochemical reaction) to…

Molecular Networks · Quantitative Biology 2010-01-28 Sitabhra Sinha , T Jesan , Nivedita Chatterjee

Near-field sensing with extremely large-scale antenna arrays (ELAAs) in practical 6G systems is expected to operate over broad bandwidths, where delay, Doppler, and spatial effects become tightly coupled across frequency. The purpose of…

Signal Processing · Electrical Eng. & Systems 2026-01-01 Tong Wei , Kumar Vijay Mishra , Bhavani Shankar M. R. , Björn Ottersten

Diffusion is a fundamental phenomenon that occurs ubiquitously in nature and remains the subject of continuous research interest. Understanding diffusion is a key to understanding leaving systems. In this Chapter, I discuss diffusion of…

Soft Condensed Matter · Physics 2018-10-15 Svyatoslav Kondrat

Statistical properties of environments experienced by biological signaling systems in the real world change, which necessitate adaptive responses to achieve high fidelity information transmission. One form of such adaptive response is gain…

Molecular Networks · Quantitative Biology 2012-05-01 Ilya Nemenman

Consider $n$ mobile sensors placed independently at random with the uniform distribution on a barrier represented as the unit line segment $[0,1]$. The sensors have identical sensing radius, say $r$. When a sensor is displaced on the line a…

Data Structures and Algorithms · Computer Science 2016-06-23 Rafał Kapelko , Evangelos Kranakis