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Under constant selection, each trait has a fixed fitness, and small mutation rates allow populations to efficiently exploit the optimal trait. Therefore it is reasonable to expect mutation rates will evolve downwards. However, we find this…

Populations and Evolution · Quantitative Biology 2022-08-23 Brian Mintz , Feng Fu

The dynamics of molecular collisions in a macroscopic body are encoded by the parameter Thermodynamic entropy - a statistical measure of the number of molecular configurations that correspond to a given macrostate. Directionality in the…

Populations and Evolution · Quantitative Biology 2020-05-22 Lloyd Demetrius , Christian Wolf

In this study the effect of parallel and random-sequential updates on the dynamical properties of flocks in one dimension is considered. It is found that the frequency of directional switching is increased for random-sequential updates as…

Statistical Mechanics · Physics 2017-04-14 R. K. Singh , Shradha Mishra

The investigation of allele frequency trajectories in populations evolving under controlled environmental pressures has become a popular approach to study evolutionary processes on the molecular level. Statistical models based on…

Machine Learning · Computer Science 2025-07-29 Julia Siekiera , Christian Schlötterer , Stefan Kramer

Stochastic models of sequential mutation acquisition are widely used to quantify cancer and bacterial evolution. Across manifold scenarios, recurrent research questions are: how many cells are there with $n$ alterations, and how long will…

Populations and Evolution · Quantitative Biology 2023-07-07 Michael D. Nicholson , David Cheek , Tibor Antal

Phenotypes of individuals in a population of organisms are not fixed. Phenotypic fluctuations, which describe temporal variation of the phenotype of an individual or individual-to-individual variation across a population, are present in…

Populations and Evolution · Quantitative Biology 2018-08-15 Hong-Yan Shih , Harry Mickalide , David T. Fraebel , Nigel Goldenfeld , Seppe Kuehn

We consider a model for Darwinian evolution in an asexual population with a large but non-constant populations size characterized by a natural birth rate, a logistic death rate modelling competition and a probability of mutation at each…

Probability · Mathematics 2015-08-28 Martina Baar , Anton Bovier , Nicolas Champagnat

We study self-replicating molecules under externally varying conditions. Changing conditions such as temperature variations and/or alterations in the environment's resource composition lead to both non-constant replication and decay rates…

Biological Physics · Physics 2016-09-08 Claus O. Wilke , Christopher Ronnewinkel , Thomas Martinetz

The exact statistics of an arbitrary quantum observable is analytically obtained. Due to the probabilistic nature of a sequence of intermediate measurements and stochastic fluctuations induced by the interaction with the environment, the…

Statistical Mechanics · Physics 2019-06-19 Stefano Gherardini

The shape of allele-frequency clines maintained by migration-selection balance depends not only on the properties of migration and selection, but also on the dominance relations among alleles and on linkage to other loci under selection. We…

Populations and Evolution · Quantitative Biology 2018-12-18 Reinhard Bürger

We propose a new approximation-technique to deal with the exact macroscopic integro-differential evolution equations of statistical systems which self-consistently accounts for dissipative effects. Concentrating on one and two point…

High Energy Physics - Phenomenology · Physics 2007-05-23 Herbert Nachbagauer

The adaptive evolution of large asexual populations is generally characterized by competition between clones carrying different beneficial mutations. This interference phenomenon slows down the adaptation speed and makes the theoretical…

Populations and Evolution · Quantitative Biology 2012-12-20 Maria Rita Fumagalli , Matteo Osella , Philippe Thomen , Francois Heslot , Marco Cosentino Lagomarsino

We consider a fitness-structured population model with competition and migration between nearest neighbors. Under a combination of large population and rare migration limits we are particularly interested in the asymptotic behavior of the…

Probability · Mathematics 2012-07-20 Anton Bovier , Shi-Dong Wang

In this paper, we study the asymptotic (large time) behavior of a selection-mutation-competition model for a population structured with respect to a phenotypic trait, when the rate of mutation is very small. We assume that the reproduction…

Analysis of PDEs · Mathematics 2015-11-17 Àngel Calsina , Sílvia Cuadrado , Laurent Desvillettes , Gaël Raoul

We consider a stochastic model of population dynamics where each individual is characterised by a trait in {0,1,...,L} and has a natural reproduction rate, a logistic death rate due to age or competition and a probability of mutation…

Probability · Mathematics 2019-02-12 Anton Bovier , Loren Coquille , Charline Smadi

Random perturbations applied in tandem to an ensemble of oscillating objects can synchronize their motion. We study multiple copies of an arbitrary dynamical system in a stable limit cycle, described via a standard phase reduction picture.…

Statistical Mechanics · Physics 2024-02-23 Yunxiang Song , Thomas A. Witten

The importance of microscopic details on cooperation level is an intensively studied aspect of evolutionary game theory. Interestingly, these details become crucial on heterogeneous populations where individuals may possess diverse traits.…

Physics and Society · Physics 2018-08-21 Attila Szolnoki , Zsuzsa Danku

We show that the naive application of the maximum entropy principle can yield answers which depend on the level of description, i.e. the result is not invariant under coarse-graining. We demonstrate that the correct approach, even for…

Statistical Mechanics · Physics 2007-05-23 Jayanth Banavar , Amos Maritan

The rich set of interactions between individuals in the society results in complex community structure, capturing highly connected circles of friends, families, or professional cliques in a social network. Thanks to frequent changes in the…

Methodology · Statistics 2007-12-12 Gergely Palla , Albert-Laszlo Barabasi , Tamas Vicsek

We introduce a multi-allele Wright-Fisher model with non-recurrent, reversible mutation and directional selection. In this setting, the allele frequencies at a single locus track the path of a hybrid jump-diffusion process with state space…

Probability · Mathematics 2023-02-16 Ingemar Kaj , Carina F. Mugal , Rebekka Müller
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