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A thorough understanding of the neuroanatomy of peripheral nerves is required for a better insight into their function and the development of neuromodulation tools and strategies. In biophysical modeling, it is commonly assumed that the…

In systems neuroscience, most models posit that brain regions communicate information under constraints of efficiency. Yet, evidence for efficient communication in structural brain networks characterized by hierarchical organization and…

Spin-based computing is emerging as a powerful approach for energy-efficient and high-performance solutions to future data processing hardware. Spintronic devices function by electrically manipulating the collective dynamics of the electron…

At large, most animal brains present two mirror-symmetric sides; but closer inspection reveals a range of asymmetries (in shape and function), that seem more salient in more cognitively complex species. Sustaining symmetric, redundant…

Neurons and Cognition · Quantitative Biology 2021-12-02 Luís F Seoane

Brain mechanics is a topic of deep interest because of the significant role of mechanical cues in both brain function and form. Specifically, capturing the heterogeneous and anisotropic behaviour of cerebral white matter (WM) is extremely…

Soft Condensed Matter · Physics 2021-10-20 Asad Jamal , Andrea Bernardini , Daniele Dini

The brain is believed to implement probabilistic reasoning and to represent information via population, or distributed, coding. Most previous population-based probabilistic (PPC) theories share several basic properties: 1) continuous-valued…

Neurons and Cognition · Quantitative Biology 2018-02-23 Gerard Rinkus

Highly-optimized complex transport networks serve crucial functions in many man-made and natural systems such as power grids and plant or animal vasculature. Often, the relevant optimization functional is non-convex and characterized by…

Biological Physics · Physics 2016-09-23 Henrik Ronellenfitsch , Eleni Katifori

The use of cortical field potentials rather than the details of spike trains as the basis for cognitive information processing is proposed. This results in a space of cognitive elements with natural metrics. Sets of spike trains may also be…

Disordered Systems and Neural Networks · Physics 2016-08-31 Henry C. Tuckwell

In many normative theories of synaptic plasticity, weight updates implicitly depend on the chosen parametrization of the weights. This problem relates, for example, to neuronal morphology: synapses which are functionally equivalent in terms…

Neurons and Cognition · Quantitative Biology 2022-02-25 Elena Kreutzer , Walter M. Senn , Mihai A. Petrovici

Mammalian functional architecture flexibly adapts, transitioning from integration where information is distributed across the cortex, to segregation where information is focal in densely connected communities of brain regions. This…

Neurons and Cognition · Quantitative Biology 2025-04-03 Kimberly Nestor

Partially inspired by features of computation in visual cortex, deep neural networks compute hierarchical representations of their inputs. While these networks have been highly successful in machine learning, it remains unclear to what…

Neurons and Cognition · Quantitative Biology 2019-11-20 Jianghong Shi , Eric Shea-Brown , Michael A. Buice

Cortical circuits are characterized by exquisitely complex connectivity patterns that emerge during development from undifferentiated networks. The development of these circuits is governed by a combination of precise molecular cues that…

Neurons and Cognition · Quantitative Biology 2020-09-15 Joseph Olson , Gabriel Kreiman

Neurons in the brain are often finely tuned for specific task variables. Moreover, such disentangled representations are highly sought after in machine learning. Here we mathematically prove that simple biological constraints on neurons,…

Neurons and Cognition · Quantitative Biology 2023-04-04 James C. R. Whittington , Will Dorrell , Surya Ganguli , Timothy E. J. Behrens

It is widely believed that the formation of brain network structure is under the pressure of optimal trade-off between reducing wiring cost and promoting communication efficiency. However, the question of whether this trade-off exists in…

Neurons and Cognition · Quantitative Biology 2020-12-10 Junji Ma , Jinbo Zhang , Ying Lin , Zhengjia Dai

Abnormal cortical folding patterns may be related to neurodevelopmental disorders such as lissencephaly and polymicrogyria. In this context, computational modeling is a powerful tool to provide a better understanding of the early brain…

Many networks in the brain are sparsely connected, and the brain eliminates synapses during development and learning. How could the brain decide which synapses to prune? In a recurrent network, determining the importance of a synapse…

Neurons and Cognition · Quantitative Biology 2021-07-20 Eli Moore , Rishidev Chaudhuri

We introduce a novel concept for spiking neural networks (SNNs) derived from the idea of "linear pieces" used to analyse the expressiveness and trainability of artificial neural networks (ANNs). We prove that the input domain of SNNs…

Neural and Evolutionary Computing · Computer Science 2025-04-22 Dominik Dold , Philipp Christian Petersen

Constellation shaping is a practical and effective technique to improve the performance and the rate adaptivity of optical communication systems. In principle, it could also be used to mitigate the impact of nonlinear effects, possibly…

Information Theory · Computer Science 2022-06-08 Marco Secondini , Stella Civelli , Enrico Forestieri , Lareb Zar Khan

For long it has been known that specific patterns of folding are necessary for an optimally functioning brain. For instance, lissencephaly and polymicrogyria can lead to severe mental retardation, short life expectancy, epileptic seizures,…

Biological Physics · Physics 2020-04-03 Lucas da Costa Campos , Raphael Hornung , Gerhard Gompper , Jens Elgeti , Svenja Caspers

Cognitive neuroscience explores the mechanisms of cognition by studying its structural and functional brain correlates. Here, we report the first systematic review that assesses how information from structural and functional neuroimaging…

Neurons and Cognition · Quantitative Biology 2022-02-07 Marta Czime Litwińczuk , Nelson Trujillo-Barreto , Nils Muhlert , Lauren Cloutman , Anna Woollams