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In this study, a two-state mechanochemical model is presented to describe the dynamic instability of microtubules (MTs) in cells. The MTs switches between two states, assembly state and disassembly state. In assembly state, the growth of…

Biological Physics · Physics 2012-03-23 Yunxin Zhang

Many sequence computations are easier to study as movement through internal states than as isolated local circuits. We introduce Markovian Circuit Tracing (MCT), a diagnostic pipeline for testing whether transformer activations contain…

Machine Learning · Computer Science 2026-05-21 Abdullah X

Distribution network topology detection and state estimation in real-time are critical for modern distribution systems management and control. However, number of sensors in distribution networks are limited and communication links between…

Optimization and Control · Mathematics 2022-09-07 Zahra Soltani , Mojdeh Khorsand

Assistive devices, such as exoskeletons and prostheses, have revolutionized the field of rehabilitation and mobility assistance. Efficiently detecting transitions between different activities, such as walking, stair ascending and…

A wide variety of physical systems ranging from the firing of neurons to eutrophication of lakes to the presence of Arctic summer sea ice exhibit a phenomenon known as tipping. In mathematical models, tipping can be caused by bifurcations,…

Dynamical Systems · Mathematics 2018-03-14 Alanna Hoyer-Leitzel , Alice Nadeau , Andrew Roberts , Andrew Steyer

Squeezing a quantum state along a specific direction has long been recognized as a crucial technique for enhancing the precision of quantum metrology by reducing parameter uncertainty. However, practical quantum metrology often involves the…

We present a new method that enables the identification and analysis of both transition and metastable conformational states from atomistic or coarse-grained molecular dynamics (MD) trajectories. Our algorithm is presented and studied by…

Chemical Physics · Physics 2017-10-04 Linda Martini , Adam Kells , Gerhard Hummer , Nicolae-Viorel Buchete , Edina Rosta

A new approach to the steady state detection in the uniformization method of solving continuous time Markov chains is introduced. The method is particularly useful in solving inhomogenous CTMC's in multiple steps, where the desired error…

Performance · Computer Science 2014-10-14 Maciej Burak

For many quantum systems intended for information processing, one detects the logical state of a qubit by integrating a continuously observed quantity over time. For example, ion and atom qubits are typically measured by driving a cycling…

Quantum Physics · Physics 2023-10-03 Shawn Geller , Daniel C. Cole , Scott Glancy , Emanuel Knill

Quantum dots (QDs) are pivotal for the development of quantum technologies, with applications ranging from single-photon sources for secure communication to quantum computing infrastructures. Understanding the electron dynamics within these…

Quantum Physics · Physics 2024-12-20 Markus Sifft , Johannes C. Bayer , Daniel Hägele , Rolf J. Haug

Many models of physics beyond the Standard Model include towers of particles whose masses follow an approximately periodic pattern with little spacing between them. These resonances might be too weak to detect individually, but could be…

High Energy Physics - Phenomenology · Physics 2020-03-18 Hugues Beauchesne , Yevgeny Kats

Micro-expressions are involuntary facial movements that cannot be consciously controlled, conveying subtle cues with substantial real-world applications. The analysis of micro-expressions generally involves two main tasks: spotting…

Computer Vision and Pattern Recognition · Computer Science 2024-09-17 Bochao Zou , Zizheng Guo , Wenfeng Qin , Xin Li , Kangsheng Wang , Huimin Ma

This paper addresses the challenge of accurately detecting the transition from the warmup phase to the steady state in performance metric time series, which is a critical step for effective benchmarking. The goal is to introduce a method…

Performance · Computer Science 2025-11-17 Martin Beseda , Vittorio Cortellessa , Daniele Di Pompeo , Luca Traini , Michele Tucci

Measurement-induced phase transition (MIPT) describes the nonanalytical change of the entanglement entropy resulting from the interplay between measurement and unitary evolution. In this paper, we investigate the relaxation critical…

Quantum Physics · Physics 2026-01-27 Wantao Wang , Shuo Liu , Jiaqiang Li , Shi-Xin Zhang , Shuai Yin

A method is proposed to identify target states that optimize a metastability index amongst a set of trial states and use these target states as milestones (or core sets) to build Markov State Models (MSMs). If the optimized metastability…

Statistical Mechanics · Physics 2016-08-03 Enrico Guarnera , Eric Vanden-Eijnden

Learning a Markov Decision Process (MDP) from a fixed batch of trajectories is a non-trivial task whose outcome's quality depends on both the amount and the diversity of the sampled regions of the state-action space. Yet, many MDPs are…

Machine Learning · Computer Science 2022-03-08 Giorgio Angelotti , Nicolas Drougard , Caroline P. C. Chanel

Molecular communication requires low-complexity symbol detection algorithms to deal with the many sources of uncertainty that are inherent in these channels. This paper proposes two variants of a high-performance asynchronous peak detection…

Information Theory · Computer Science 2017-02-27 Adam Noel , Andrew W. Eckford

We develop a framework for detecting regime transitions in dynamical systems using the Mixup Euler Characteristic Profile (Mixup ECP) -- the Euler characteristic of the geometric intersection of ball unions around adjacent delay-embedded…

Dynamical Systems · Mathematics 2026-04-17 Sushovan Majhi , Atish Mitra , Santanu Nandi , Md Nurujjaman , Buddha Nath Sharma

A novel theoretical model of dynamic instability of a system of linear (1D) microtubules (MTs) in a bounded domain is introduced for studying the role of a cell edge in vivo and analyzing the effect of competition for a limited amount of…

Subcellular Processes · Quantitative Biology 2007-05-23 Gennady Margolin , Ivan V. Gregoretti , Holly V. Goodson , Mark S. Alber

Spin-triplet superconductivity (SC) offers a unique avenue for realizing non-Abelian Majorana zero modes and thus the fault-tolerant topological quantum computation, and has attracted a broad audience for both fundamental research and…

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