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Related papers: Recent Developments in Methods for Identifying Rea…

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Detecting rare events, those defined to give rise to high impact but have a low probability of occurring, is a challenge in a number of domains including meteorological, environmental, financial and economic. The use of machine learning to…

Applications · Statistics 2022-09-13 Santhosh Narayanan , Carsten Maple , Mark Hooper

Computational techniques are required for narrowing down the vast space of possibilities to plausible prebiotic scenarios, since precise information on the molecular composition, the dominant reaction chemistry, and the conditions for that…

Molecular Networks · Quantitative Biology 2018-02-07 Jakob L. Andersen , Christoph Flamm , Daniel Merkle , Peter F. Stadler

With the rise of service-oriented computing, applications are more and more based on coordination of autonomous services. Envisioned over largely distributed and highly dynamic platforms, expressing this coordination calls for alternative…

Distributed, Parallel, and Cluster Computing · Computer Science 2012-03-15 Marin Bertier , Marko Obrovac , Cédric Tedeschi

In a stochastic reaction network setting we consider the problem of tracking the fate of individual molecules. We show that using the classical large volume limit results, we may approximate the dynamics of a single tracked molecule in a…

Probability · Mathematics 2023-01-05 Daniele Cappelletti , Grzegorz A. Rempala

Stochastic simulation is a widely used method for estimating quantities in models of chemical reaction networks where uncertainty plays a crucial role. However, reducing the statistical uncertainty of the corresponding estimators requires…

Quantitative Methods · Quantitative Biology 2019-06-13 Michael Backenköhler , Luca Bortolussi , Verena Wolf

As an optimal one-dimensional reaction coordinate, the committor function not only describes the probability of a trajectory initiated at a phase space point first reaching the product state before reaching the reactant state, but also…

Chemical Physics · Physics 2024-10-08 Xiaojun Ji , Ru Wang , Hao Wang , Wenjian Liu

Contact processes describe the transmission of distinct properties of nodes via the links of a network. They provide a simple framework for many phenomena, such as epidemic spreading and opinion formation. Combining contact processes with…

Physics and Society · Physics 2010-11-12 Anne-Ly Do , Thilo Gross

To perform recognition, molecules must locate and specifically bind their targets within a noisy biochemical environment with many look-alikes. Molecular recognition processes, especially the induced-fit mechanism, are known to involve…

Biomolecules · Quantitative Biology 2010-07-27 Yonatan Savir , Tsvi Tlusty

With the rise of data-centric process management paradigms, interdependent processes, such as artifacts or object lifecycles, form a business process through their interactions. Coordination processes may be used to coordinate these…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-12-16 Sebastian Steinau , Kevin Andrews , Manfred Reichert

The definition of heat in quantum mechanics is ambiguous. Complications arise in particular when the coupling between a quantum system and a thermal environment is non-negligible, as the boundary between the two becomes blurred, making the…

Quantum Physics · Physics 2025-08-20 Mike Shubrook , Jake Iles-Smith , Ahsan Nazir

The formation and dissociation of specific noncovalent interactions between a variety of macromolecules play a crucial role in the function of biological systems. During the last few years, three main lines of research led to a dramatic…

Biological Physics · Physics 2009-11-13 Pierre Bongrand

The dynamical systems found in Nature are rarely isolated. Instead they interact and influence each other. The coupling functions that connect them contain detailed information about the functional mechanisms underlying the interactions and…

Adaptation and Self-Organizing Systems · Physics 2017-11-15 Tomislav Stankovski , Tiago Pereira , Peter V. E. McClintock , Aneta Stefanovska

As a complement to experimental and theoretical approaches, numerical modeling has become an important component to study asteroid collisions and impact processes. In the last decade, there have been significant advances in both…

Earth and Planetary Astrophysics · Physics 2019-08-07 Martin Jutzi , Keith Holsapple , Kai Wünneman , Patrick Michel

In these notes we collect some results from several of the authors' works in order to make available a single source and show how the approximate geometric methods for regulation have been developed, and how the control design strategy has…

Optimization and Control · Mathematics 2022-11-07 Eugenio Aulisa , David S. Gilliam

Recent applications of machine learning and statistical inference provide case studies demonstrating how such approaches can accelerate the discovery process in physical chemistry and related fields. Examples discussed in this review…

Chemical Physics · Physics 2017-06-20 Ryan B. Jadrich , Beth A. Lindquist , Thomas M. Truskett

Estimating the probability of failures or accidents with aerospace systems is often necessary when new concepts or designs are introduced, as it is being done for Autonomous Aircraft. If the design is safe, as it is supposed to be, accident…

Applications · Statistics 2018-08-10 Ítalo Romani de Oliveira , Jeffery Musiak

We propose an efficient novel path sampling-based framework designed to accelerate the investigation of rare events in complex molecular systems. A key innovation is the shift from sampling restricted path ensemble distributions, as in…

Chemical Physics · Physics 2025-03-28 Gianmarco Lazzeri , Peter G. Bolhuis , Roberto Covino

The method of integral transforms is reviewed. In the framework of this method reaction observables are obtained with the bound--state calculation techniques. New developments are reported.

Nuclear Theory · Physics 2007-05-23 V. D. Efros

Moment closure methods appear in myriad scientific disciplines in the modelling of complex systems. The goal is to achieve a closed form of a large, usually even infinite, set of coupled differential (or difference) equations. Each equation…

Statistical Mechanics · Physics 2018-12-24 Christian Kuehn

The analysis of complex reaction networks is of great importance in several chemical and biochemical fields (interstellar chemistry, prebiotic chemistry, reaction mechanism, etc). In this article, we propose to simultaneously refine and…

Molecular Networks · Quantitative Biology 2008-03-11 Raphaël Plasson , Hugues Bersini , Axel Brandenburg
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