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The representations learned by deep neural networks are difficult to interpret in part due to their large parameter space and the complexities introduced by their multi-layer structure. We introduce a method for computing persistent…

Machine Learning · Computer Science 2019-05-31 Thomas Gebhart , Paul Schrater , Alan Hylton

This paper introduces an unsupervised method to estimate the class separability of text datasets from a topological point of view. Using persistent homology, we demonstrate how tracking the evolution of embedding manifolds during training…

Machine Learning · Computer Science 2024-06-19 Kostis Gourgoulias , Najah Ghalyan , Maxime Labonne , Yash Satsangi , Sean Moran , Joseph Sabelja

Prediction and discovery of new materials with desired properties are at the forefront of quantum science and technology research. A major bottleneck in this field is the computational resources and time complexity related to finding new…

We redevelop persistent homology (topological persistence) from a categorical point of view. The main objects of study are diagrams, indexed by the poset of real numbers, in some target category. The set of such diagrams has an interleaving…

Algebraic Topology · Mathematics 2014-05-13 Peter Bubenik , Jonathan A. Scott

Recurrent neural networks are powerful tools for understanding and modeling computation and representation by populations of neurons. Continuous-variable or "rate" model networks have been analyzed and applied extensively for these…

Neurons and Cognition · Quantitative Biology 2016-01-29 Brian DePasquale , Mark M. Churchland , L. F. Abbott

Recently a new feature representation and data analysis methodology based on a topological tool called persistent homology (and its corresponding persistence diagram summary) has started to attract momentum. A series of methods have been…

Computational Geometry · Computer Science 2019-12-13 Qi Zhao , Yusu Wang

We use methods from computational algebraic topology to study functional brain networks, in which nodes represent brain regions and weighted edges encode the similarity of fMRI time series from each region. With these tools, which allow one…

Quantitative Methods · Quantitative Biology 2020-08-27 Bernadette J. Stolz , Tegan Emerson , Satu Nahkuri , Mason A. Porter , Heather A. Harrington

In the wake of recent advances in experimental methods in neuroscience, the ability to record in-vivo neuronal activity from awake animals has become feasible. The availability of such rich and detailed physiological measurements calls for…

Quantitative Methods · Quantitative Biology 2016-11-03 Gal Mishne , Ronen Talmon , Ron Meir , Jackie Schiller , Uri Dubin , Ronald R. Coifman

Within the context of topological data analysis, the problems of identifying topological significance and matching signals across datasets are important and useful inferential tasks in many applications. The limitation of existing solutions…

Algebraic Topology · Mathematics 2024-06-26 Inés García-Redondo , Anthea Monod , Anna Song

We introduce a novel set of observables associated to the rapidly developing field of persistent homology for the quantitative characterization of nuclear collisions and their evolution. Persistent homology allows for the identification of…

Nuclear Theory · Physics 2023-01-04 Greg Hamilton , Travis Dore , Christopher Plumberg

Persistent homology is a popular tool in Topological Data Analysis. It provides numerical characteristics of data sets which reflect global geometric properties. In order to be useful in practice, for example for feature generation in…

Computational Geometry · Computer Science 2020-02-17 Boris Goldfarb

We present a topological framework for analysing neural time series that integrates Transfer Entropy (TE) with directed Persistent Homology (PH) to characterize information flow in spiking neural systems. TE quantifies directional influence…

Neurons and Cognition · Quantitative Biology 2025-08-27 Dylan Peek , Siddharth Pritam , Matthew P. Skerritt , Stephan Chalup

Fitting network models to neural activity is an important tool in neuroscience. A popular approach is to model a brain area with a probabilistic recurrent spiking network whose parameters maximize the likelihood of the recorded activity.…

Machine Learning · Statistics 2021-11-16 Guillaume Bellec , Shuqi Wang , Alireza Modirshanechi , Johanni Brea , Wulfram Gerstner

We prove an extension to the simplicial Nerve Lemma which establishes isomorphism of persistent homology groups, in the case where the covering spaces are filtered. While persistent homology is now widely used in topological data analysis,…

Algebraic Topology · Mathematics 2012-02-29 Maia Fraser

Background: Current neuronal monitoring techniques, such as calcium imaging and multi-electrode arrays, enable recordings of spiking activity from hundreds of neurons simultaneously. Of primary importance in systems neuroscience is the…

Neurons and Cognition · Quantitative Biology 2014-11-11 Yazan N. Billeh , Michael T. Schaub , Costas A. Anastassiou , Mauricio Barahona , Christof Koch

Natural data offer a hard challenge to data analysis. One set of tools is being developed by several teams to face this difficult task: Persistent topology. After a brief introduction to this theory, some applications to the analysis and…

Algebraic Topology · Mathematics 2017-08-21 Massimo Ferri

Persistent homology captures the evolution of topological features of a model as a parameter changes. The most commonly used summary statistics of persistent homology are the barcode and the persistence diagram. Another summary statistic,…

Methodology · Statistics 2016-04-01 Violeta Kovacev-Nikolic , Peter Bubenik , Dragan Nikolić , Giseon Heo

Information encoding in the nervous system is supported through the precise spike-timings of neurons; however, an understanding of the underlying processes by which such representations are formed in the first place remains unclear. Here we…

Neural and Evolutionary Computing · Computer Science 2015-12-01 Brian Gardner , Ioana Sporea , André Grüning

This paper exploits the fact that the variability in the inter-spike intervals, in the spike train issuing from a neuron, carries substantial information regarding the input to the neuron. A framework for neuronal information processing is…

Neurons and Cognition · Quantitative Biology 2008-08-04 Balaram Das

Persistent homology is a popular technique in topological data analysis that tracks the lifespans of homological features in a nested sequence of spaces. This data is typically presented in a multi-set called a persistence diagram or a…

Algebraic Topology · Mathematics 2025-11-26 Deni Salja
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