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This work considers the method of uniformisation for continuous-time Markov chains in the context of chemical reaction networks. Previous work in the literature has shown that uniformisation can be beneficial in the context of…

Quantitative Methods · Quantitative Biology 2019-04-18 Casper Beentjes , Ruth Baker

Model order reduction (MOR) methods that are designed to preserve structural features of a given full order model (FOM) often suffer from a lower accuracy when compared to their non-structure-preserving counterparts. In this paper, we…

Systems and Control · Electrical Eng. & Systems 2022-05-17 Paul Schwerdtner , Matthias Voigt

In the wake of the explosive growth in smartphones and cyberphysical systems, there has been an accelerating shift in how data is generated away from centralised data towards on-device generated data. In response, machine learning…

Machine Learning · Computer Science 2021-12-09 Ross Drummond , Mathew C. Turner , Stephen R. Duncan

The recently proposed multi-layer sparse model has raised insightful connections between sparse representations and convolutional neural networks (CNN). In its original conception, this model was restricted to a cascade of convolutional…

Image and Video Processing · Electrical Eng. & Systems 2018-07-26 Aviad Aberdam , Jeremias Sulam , Michael Elad

Model-based prediction of stochastic noise in biomolecular reactions often resorts to approximation with unknown precision. As a result, unexpected stochastic fluctuation causes a headache for the designers of biomolecular circuits. This…

Molecular Networks · Quantitative Biology 2018-08-07 Yuta Sakurai , Yutaka Hori

A detailed algorithmic explanation is required for how a network of chemical reactions can generate the sophisticated behavior displayed by living cells. Though several previous works have shown that reaction networks are computationally…

Emerging Technologies · Computer Science 2018-04-25 Muppirala Viswa Virinchi , Abhishek Behera , Manoj Gopalkrishnan

An emerging application of Raman spectroscopy is monitoring the state of chemical reactors during biologic drug production. Raman shift intensities scale linearly with the concentrations of chemical species and thus can be used to…

Signal Processing · Electrical Eng. & Systems 2023-06-30 Dexter Antonio , Hannah O'Toole , Randy Carney , Ambarish Kulkarni , Ahmet Palazoglu

A novel neural network (NN) approach is proposed for constrained optimization. The proposed method uses a specially designed NN architecture and training/optimization procedure called Neural Optimization Machine (NOM). The objective…

Machine Learning · Statistics 2022-08-10 Jie Chen , Yongming Liu

We propose a projection-based model order reduction procedure for the ageing of large prestressed concrete structures. Our work is motivated by applications in the nuclear industry, particularly in the simulation of containment buildings.…

Structured learning is appropriate when predicting structured outputs such as trees, graphs, or sequences. Most prior work requires the training set to consist of complete trees, graphs or sequences. Specifying such detailed ground truth…

Machine Learning · Computer Science 2012-07-03 Xinghua Lou , Fred Hamprecht

Chemical kinetics plays an important role in governing the thermal evolution in reactive flows problems. The possible interactions between chemical species increase drastically with the number of species considered in the system. Various…

Instrumentation and Methods for Astrophysics · Physics 2022-07-18 Kwok Sun Tang , Matthew Turk

Lattice-like structures can provide a combination of high stiffness with light weight that is useful in many applications, but a resolved finite element mesh of such structures results in a computationally expensive discretization. This…

Numerical Analysis · Mathematics 2022-09-07 Sean McBane , Youngsoo Choi , Karen Willcox

With the rise of deep learning technology in practical applications, Convolutional Neural Networks (CNNs) have been able to assist humans in solving many real-world problems. To enhance the performance of CNNs, numerous network…

Machine Learning · Computer Science 2024-09-10 Qi Wang , Zijun Gao , Mingxiu Sui , Taiyuan Mei , Xiaohan Cheng , Iris Li

For many applications in signal processing and machine learning, we are tasked with minimizing a large sum of convex functions subject to a large number of convex constraints. In this paper, we devise a new random projection method (RPM) to…

Optimization and Control · Mathematics 2024-04-08 Zhichun Yang , Fu-quan Xia , Kai Tu , Man-Chung Yue

Sparse coding consists in representing signals as sparse linear combinations of atoms selected from a dictionary. We consider an extension of this framework where the atoms are further assumed to be embedded in a tree. This is achieved…

Machine Learning · Statistics 2011-08-18 Rodolphe Jenatton , Julien Mairal , Guillaume Obozinski , Francis Bach

We propose a provably convergent method, called Efficient Learned Descent Algorithm (ELDA), for low-dose CT (LDCT) reconstruction. ELDA is a highly interpretable neural network architecture with learned parameters and meanwhile retains…

Image and Video Processing · Electrical Eng. & Systems 2021-04-28 Qingchao Zhang , Mehrdad Alvandipour , Wenjun Xia , Yi Zhang , Xiaojing Ye , Yunmei Chen

It is known that certain structures of the signal in addition to the standard notion of sparsity (called structured sparsity) can improve the sample complexity in several compressive sensing applications. Recently, Hegde et al. proposed a…

Information Theory · Computer Science 2017-01-23 Lingxiao Huang , Yifei Jin , Jian Li , Haitao Wang

Combinatorial optimization (CO) problems, central to operation research and theoretical computer science, present significant computational challenges due to their NP-hard nature. While large language models (LLMs) have emerged as promising…

Machine Learning · Computer Science 2025-06-16 Xijun Li , Jiexiang Yang , Jinghao Wang , Bo Peng , Jianguo Yao , Haibing Guan

The Security-Constrained Economic Dispatch (SCED) is a fundamental optimization model for Transmission System Operators (TSO) to clear real-time energy markets while ensuring reliable operations of power grids. In a context of growing…

Machine Learning · Computer Science 2021-12-28 Wenbo Chen , Seonho Park , Mathieu Tanneau , Pascal Van Hentenryck

Approximating a function with a finite series, e.g., involving polynomials or trigonometric functions, is a critical tool in computing and data analysis. The construction of such approximations via now-standard approaches like least squares…

Optimization and Control · Mathematics 2021-08-30 Dihan Dai , Yekaterina Epshteyn , Akil Narayan