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Finite Gaussian mixture models are widely used for model-based clustering of continuous data. Nevertheless, since the number of model parameters scales quadratically with the number of variables, these models can be easily…

Methodology · Statistics 2018-09-25 Michael Fop , Thomas Brendan Murphy , Luca Scrucca

The rapid development of high-throughput technologies has enabled the generation of data from biological or disease processes that span multiple layers, like genomic, proteomic or metabolomic data, and further pertain to multiple sources,…

Machine Learning · Statistics 2022-01-25 Subhabrata Majumdar , George Michailidis

Longitudinal brain imaging data facilitate the monitoring of structural and functional alterations in individual brains across time, offering essential understanding of dynamic neurobiological mechanisms. Such data improve sensitivity for…

Applications · Statistics 2026-02-04 Zhentao Yu , Jiaqi Ding , Guorong Wu , Quefeng Li

Learning the relationships between various entities from time-series data is essential in many applications. Gaussian graphical models have been studied to infer these relationships. However, existing algorithms process data in a batch at a…

Machine Learning · Computer Science 2021-10-04 Tong Yao , Shreyas Sundaram

We consider inference for misaligned multivariate functional data that represents the same underlying curve, but where the functional samples have systematic differences in shape. In this paper we introduce a new class of generally…

Applications · Statistics 2023-01-23 Niels Lundtorp Olsen , Bo Markussen , Lars Lau Rakêt

Graphical models have proven to be powerful tools for representing high-dimensional systems of random variables. One example of such a model is the undirected graph, in which lack of an edge represents conditional independence between two…

Probability · Mathematics 2013-10-11 Dhafer Malouche , Bala Rajaratnam , Benjamin T. Rolfs

In a mixed generalized linear model, the goal is to learn multiple signals from unlabeled observations: each sample comes from exactly one signal, but it is not known which one. We consider the prototypical problem of estimating two…

Statistics Theory · Mathematics 2026-01-12 Yihan Zhang , Marco Mondelli , Ramji Venkataramanan

Structural equation modeling (SEM) is a popular tool in the social and behavioural sciences, where it is being applied to ever more complex data types. The high-dimensional data produced by modern sensors, brain images, or (epi)genetic…

Methodology · Statistics 2019-10-11 Erik-Jan van Kesteren , Daniel L. Oberski

In this work, we present a new approach for constructing models for correlation matrices with a user-defined graphical structure. The graphical structure makes correlation matrices interpretable and avoids the quadratic increase of…

We introduce a framework for automatically defining and learning deep generative models with problem-specific structure. We tackle problem domains that are more traditionally solved by algorithms such as sorting, constraint satisfaction for…

Machine Learning · Computer Science 2023-06-21 Christian Weilbach , William Harvey , Frank Wood

Spectral analysis plays a crucial role in high-dimensional statistics, where determining the asymptotic distribution of various spectral statistics remains a challenging task. Due to the difficulties of deriving the analytic form, recent…

Statistics Theory · Mathematics 2025-04-02 Guoyu Zhang , Dandan Jiang , Fang Yao

We consider the problem of parameter estimation in a high-dimensional generalized linear model. Spectral methods obtained via the principal eigenvector of a suitable data-dependent matrix provide a simple yet surprisingly effective…

Statistics Theory · Mathematics 2025-07-11 Yihan Zhang , Hong Chang Ji , Ramji Venkataramanan , Marco Mondelli

This paper introduces a general framework for estimating variance components in the linear mixed models via general unbiased estimating equations, which include some well-used estimators such as the restricted maximum likelihood estimator.…

Methodology · Statistics 2021-05-18 Tatsuya Kubokawa , Shonosuke Sugasawa , Hiromasa Tamae , Sanjay Chaudhuri

We propose an estimation approach to analyse correlated functional data which are observed on unequal grids or even sparsely. The model we use is a functional linear mixed model, a functional analogue of the linear mixed model. Estimation…

Methodology · Statistics 2015-08-10 Jona Cederbaum , Marianne Pouplier , Phil Hoole , Sonja Greven

Covariate adjustment is a commonly used method for total causal effect estimation. In recent years, graphical criteria have been developed to identify all valid adjustment sets, that is, all covariate sets that can be used for this purpose.…

Statistics Theory · Mathematics 2022-05-11 Leonard Henckel , Emilija Perković , Marloes H. Maathuis

In this paper we propose a new method to learn the underlying acyclic mixed graph of a linear non-Gaussian structural equation model given observational data. We build on an algorithm proposed by Wang and Drton, and we show that one can…

Machine Learning · Computer Science 2020-10-13 Yiheng Liu , Elina Robeva , Huanqing Wang

Motivated by normalizing DNA microarray data and by predicting the interest rates, we explore nonparametric estimation of additive models with highly correlated covariates. We introduce two novel approaches for estimating the additive…

Statistics Theory · Mathematics 2010-10-05 Jiancheng Jiang , Yingying Fan , Jianqing Fan

To unbiasedly estimate a causal effect on an outcome unconfoundedness is often assumed. If there is sufficient knowledge on the underlying causal structure then existing confounder selection criteria can be used to select subsets of the…

Methodology · Statistics 2017-03-20 Jenny Häggström

Undirected graphical models are widely used to model the conditional independence structure of vector-valued data. However, in many modern applications, for example those involving EEG and fMRI data, observations are more appropriately…

Machine Learning · Statistics 2024-01-29 Boxin Zhao , Percy S. Zhai , Y. Samuel Wang , Mladen Kolar

In this self-contained chapter, we revisit a fundamental problem of multivariate statistics: estimating covariance matrices from finitely many independent samples. Based on massive Multiple-Input Multiple-Output (MIMO) systems we illustrate…

Statistics Theory · Mathematics 2021-06-14 Johannes Maly , Tianyu Yang , Sjoerd Dirksen , Holger Rauhut , Giuseppe Caire