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The importance of clinical variables in the prognosis of the disease is explained using statistical correlation or machine learning (ML). However, the predictive importance of these variables may not represent their causal relationships…

Machine Learning · Statistics 2025-06-04 Yina Hou , Shourav B. Rabbani , Liang Hong , Norou Diawara , Manar D. Samad

Causal inference analysis is the estimation of the effects of actions on outcomes. In the context of healthcare data this means estimating the outcome of counter-factual treatments (i.e. including treatments that were not observed) on a…

Methodology · Statistics 2018-03-21 Yishai Shimoni , Chen Yanover , Ehud Karavani , Yaara Goldschmnidt

Randomised controlled trials (RCTs) are the most effective approach to causal discovery, but in many circumstances it is impossible to conduct RCTs. Therefore observational studies based on passively observed data are widely accepted as an…

Artificial Intelligence · Computer Science 2016-11-11 Jiuyong Li , Thuc Duy Le , Lin Liu , Jixue Liu , Zhou Jin , Bingyu Sun , Saisai Ma

Hierarchical reinforcement learning (HRL) improves the efficiency of long-horizon reinforcement-learning tasks with sparse rewards by decomposing the task into a hierarchy of subgoals. The main challenge of HRL is efficient discovery of the…

Machine Learning · Computer Science 2025-07-08 Sadegh Khorasani , Saber Salehkaleybar , Negar Kiyavash , Matthias Grossglauser

Causal inference is capable of estimating the treatment effect (i.e., the causal effect of treatment on the outcome) to benefit the decision making in various domains. One fundamental challenge in this research is that the treatment…

Machine Learning · Computer Science 2021-12-28 Qian Li , Zhichao Wang , Shaowu Liu , Gang Li , Guandong Xu

In this paper, we study causal inference when the treatment variable is an aggregation of multiple sub-treatment variables. Researchers often report marginal causal effects for the aggregated treatment, implicitly assuming that the target…

Econometrics · Economics 2026-01-08 Carolina Caetano , Gregorio Caetano , Brantly Callaway , Derek Dyal

The framework of causal models provides a principled approach to causal reasoning, applied today across many scientific domains. Here we present this framework in the language of string diagrams, interpreted formally using category theory.…

Logic in Computer Science · Computer Science 2023-04-18 Robin Lorenz , Sean Tull

Our aging population increasingly suffers from multiple chronic diseases simultaneously, necessitating the comprehensive treatment of these conditions. Finding the optimal set of drugs for a combinatorial set of diseases is a combinatorial…

Artificial Intelligence · Computer Science 2016-11-16 Pranjul Yadav , Lisiane Prunelli , Alexander Hoff , Michael Steinbach , Bonnie Westra , Vipin Kumar , Gyorgy Simon

The unit selection problem aims to identify a set of individuals who are most likely to exhibit a desired mode of behavior, for example, selecting individuals who would respond one way if encouraged and a different way if not encouraged.…

Artificial Intelligence · Computer Science 2021-09-17 Ang Li , Judea Pearl

The causal effect of a treatment can vary from person to person based on their individual characteristics and predispositions. Mining for patterns of individual-level effect differences, a problem known as heterogeneous treatment effect…

Machine Learning · Computer Science 2019-09-04 Christopher Tran , Elena Zheleva

Causal inference is the process of estimating the effect or impact of a treatment on an outcome with other covariates as potential confounders (and mediators) that may need to be controlled. The vast majority of existing methods and systems…

Computation and Language · Computer Science 2022-05-05 Arun S. Maiya

Machine Learning (ML) has become an integral aspect of many real-world applications. As a result, the need for responsible machine learning has emerged, focusing on aligning ML models to ethical and social values, while enhancing their…

Machine Learning · Computer Science 2024-02-06 Raha Moraffah , Paras Sheth , Saketh Vishnubhatla , Huan Liu

When performing regression or classification, we are interested in the conditional probability distribution for an outcome or class variable Y given a set of explanatoryor input variables X. We consider Bayesian models for this task. In…

Machine Learning · Computer Science 2013-02-08 David Heckerman , Christopher Meek

When performing causal discovery, assumptions have to be made on how the true causal mechanism corresponds to the underlying joint probability distribution. These assumptions are labeled as causal razors in this work. We review numerous…

Machine Learning · Computer Science 2023-08-09 Wai-yin Lam

When treatments are non-randomly assigned, continuous, and yield heterogeneous effects at the same intensity, causal identification becomes particularly challenging. In such contexts, existing approaches often fail to provide…

Econometrics · Economics 2026-03-05 Augusto Cerqua , Roberta Di Stefano , Raffaele Mattera

Causal Bayesian networks are 'causal' models since they make predictions about interventional distributions. To connect such causal model predictions to real-world outcomes, we must determine which actions in the world correspond to which…

Machine Learning · Statistics 2025-02-04 Frederik Hytting Jørgensen , Luigi Gresele , Sebastian Weichwald

Causal classification models are adopted across a variety of operational business processes to predict the effect of a treatment on a categorical business outcome of interest depending on the process instance characteristics. This allows…

Machine Learning · Computer Science 2021-01-06 Diego Olaya , Wouter Verbeke , Jente Van Belle , Marie-Anne Guerry

Work in machine learning and statistics commonly focuses on building models that capture the vast majority of data, possibly ignoring a segment of the population as outliers. However, there does not often exist a good model on the whole…

Machine Learning · Computer Science 2019-07-11 Diego Calderon , Brendan Juba , Sirui Li , Zongyi Li , Lisa Ruan

In the causal learning setting, we wish to learn cause-and-effect relationships between variables such that we can correctly infer the effect of an intervention. While the difference between a cyclic structure and an acyclic structure may…

Machine Learning · Computer Science 2020-07-27 Katie Everett , Ian Fischer

In text classification tasks, models often rely on spurious correlations for predictions, incorrectly associating irrelevant features with the target labels. This issue limits the robustness and generalization of models, especially when…

Machine Learning · Computer Science 2025-02-04 Yuqing Zhou , Ziwei Zhu