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Purpose: We propose a general framework for quantifying predictive uncertainties of dose-related quantities and leveraging this information in a dose mimicking problem in the context of automated radiation therapy treatment planning.…

Medical Physics · Physics 2021-09-08 Tianfang Zhang , Rasmus Bokrantz , Jimmy Olsson

Human coders assign standardized medical codes to clinical documents generated during patients' hospitalization, which is error-prone and labor-intensive. Automated medical coding approaches have been developed using machine learning…

Computation and Language · Computer Science 2022-09-13 Wei Sun , Shaoxiong Ji , Erik Cambria , Pekka Marttinen

Background: Healthcare has many manual processes that can benefit from automation and augmentation with Generative Artificial Intelligence (AI), the medical billing and coding process. However, current foundational Large Language Models…

Self-consistency-based approaches, which involve repeatedly sampling multiple outputs and selecting the most consistent one as the final response, prove to be remarkably effective in improving the factual accuracy of large language models.…

Computation and Language · Computer Science 2025-01-24 Yi Cheng , Xiao Liang , Yeyun Gong , Wen Xiao , Song Wang , Yuji Zhang , Wenjun Hou , Kaishuai Xu , Wenge Liu , Wenjie Li , Jian Jiao , Qi Chen , Peng Cheng , Wayne Xiong

Analytical code is essential for reproducing diagnostic and prognostic prediction model research, yet code availability in the published literature remains limited. While the TRIPOD statements set standards for reporting prediction model…

Particle-in-cell methods with stochastic collision models are commonly used to simulate collisional plasma dynamics, with applications ranging from hypersonic flight to semiconductor manufacturing. Code verification of such methods is…

Computational Physics · Physics 2026-05-26 Brian A. Freno , William J. McDoniel , Christopher H. Moore , Neil R. Matula

Evaluation and Management (E/M) coding, under the Current Procedural Terminology (CPT) taxonomy, documents medical services provided to patients by physicians. Used primarily for billing purposes, it is in physicians' best interest to…

Artificial Intelligence · Computer Science 2025-10-30 Islam Nassar , Yang Lin , Yuan Jin , Rongxin Zhu , Chang Wei Tan , Zenan Zhai , Nitika Mathur , Thanh Tien Vu , Xu Zhong , Long Duong , Yuan-Fang Li

This study proposes a simple technique for propensity score matching for multiple treatment levels under the strong unconfoundedness assumption with the help of the Aitchison distance proposed in the field of compositional data analysis…

Econometrics · Economics 2017-10-25 Hajime Seya , Takahiro Yoshida

The propensity score is a common tool for estimating the causal effect of a binary treatment in observational data. In this setting, matching, subclassification, imputation, or inverse probability weighting on the propensity score can…

Methodology · Statistics 2018-01-03 Michael J Lopez , Roee Gutman

Single-cell technologies enable comprehensive profiling of diverse immune cell-types through the measurement of multiple genes or proteins per individual cell. In order to translate immune signatures assayed from blood or tissue into…

Machine Learning · Computer Science 2024-11-26 Chi-Jane Chen , Haidong Yi , Natalie Stanley

The International Classification of Diseases (ICD) serves as a definitive medical classification system encompassing a wide range of diseases and conditions. The primary objective of ICD indexing is to allocate a subset of ICD codes to a…

Computation and Language · Computer Science 2024-05-30 Xindi Wang , Robert E. Mercer , Frank Rudzicz

Healthcare data often come from multiple sites in which the correlations between confounding variables can vary widely. If deep learning models exploit these unstable correlations, they might fail catastrophically in unseen sites. Although…

Machine Learning · Computer Science 2023-10-25 Minh Nguyen , Alan Q. Wang , Heejong Kim , Mert R. Sabuncu

Uncertainty quantification of causal effects is crucial for safety-critical applications such as personalized medicine. A powerful approach for this is conformal prediction, which has several practical benefits due to model-agnostic…

Machine Learning · Computer Science 2026-02-04 Maresa Schröder , Dennis Frauen , Jonas Schweisthal , Konstantin Heß , Valentyn Melnychuk , Stefan Feuerriegel

In the context of the Electronic Health Record, automated diagnosis coding of patient notes is a useful task, but a challenging one due to the large number of codes and the length of patient notes. We investigate four models for assigning…

Computation and Language · Computer Science 2017-11-22 Tal Baumel , Jumana Nassour-Kassis , Raphael Cohen , Michael Elhadad , No`emie Elhadad

Many programmers, when they encounter an error, would like to have the benefit of automatic fix suggestions---as long as they are, most of the time, adequate. Initial research in this direction has generally limited itself to specific…

Software Engineering · Computer Science 2015-03-18 Yu Pei , Yi Wei , Carlo A. Furia , Martin Nordio , Bertrand Meyer

Motivation: Phenotype concept recognition (CR) is a fundamental task in biomedical text mining. However, existing methods either require ontology-specific training, making them struggle to generalize across diverse text styles and evolving…

Computation and Language · Computer Science 2026-04-06 Yicheng Tao , Yuanhao Huang , Yiqun Wang , Xin Luo , Jie Liu

Objective. Epidemiological studies require data that are in alignment with the classifications established for occupations or economic activities. The classifications usually include hundreds of codes and titles. Manual coding of raw data…

Computation and Language · Computer Science 2020-12-15 Nenad Savic , Nicolas Bovio , Fabian Gilbert , Irina Guseva Canu

Clinical coding is currently a labour-intensive, error-prone, but critical administrative process whereby hospital patient episodes are manually assigned codes by qualified staff from large, standardised taxonomic hierarchies of codes.…

Machine Learning · Computer Science 2023-02-28 Thomas Searle , Zina Ibrahim , Richard JB Dobson

Code super-optimization is the task of transforming any given program to a more efficient version while preserving its input-output behaviour. In some sense, it is similar to the paraphrase problem from natural language processing where the…

Machine Learning · Computer Science 2017-06-29 Rudy Bunel , Alban Desmaison , M. Pawan Kumar , Philip H. S. Torr , Pushmeet Kohli

Applied researchers in biomedicine and related fields are often interested in estimating the causal effect of a treatment or intervention. Although randomized clinical trials are considered the gold standard for establishing causal effects,…