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Locating bugs is challenging but one of the most important activities in software development and maintenance phase because there are no certain rules to identify all types of bugs. Existing automatic bug localization tools use various…

Software Engineering · Computer Science 2018-02-21 Saikat Chakraborty , Yujian Li , Matt Irvine , Ripon Saha , Baishakhi Ray

A taxonomy is a standardized framework to classify and organize items into categories. Hierarchical taxonomies are ubiquitous, ranging from the classification of organisms to the file system on a computer. Characterizing the typical…

Physics and Society · Physics 2016-11-15 Guido D'Amico , Raul Rabadan , Matthew Kleban

For statistical learning, categorical variables in a table are usually considered as discrete entities and encoded separately to feature vectors, e.g., with one-hot encoding. "Dirty" non-curated data gives rise to categorical variables with…

Machine Learning · Computer Science 2018-06-05 Patricio Cerda , Gaël Varoquaux , Balázs Kégl

Across all kingdoms of biological life, protein-coding genes exhibit unequal usage of synonmous codons. Although alternative theories abound, translational selection has been accepted as an important mechanism that shapes the patterns of…

Genomics · Quantitative Biology 2008-03-04 Julius B. Lucks , David R. Nelson , Grzegorz Kudla , Joshua B. Plotkin

It has been known for some years that entanglement entropy obtained from partial trace does not provide the correct entanglement measure when applied to systems of identical particles. Several criteria have been proposed that have the…

High Energy Physics - Theory · Physics 2013-03-05 A. P. Balachandran , T. R. Govindarajan , Amilcar R. de Queiroz , A. F. Reyes-Lega

In this paper it is shown that within a Combined Genetic Code Table, realized through a combination of Watson-Crick Table and Codon Path Cube it exists, without an exception, a strict distinction between two classes of enzymes…

Genomics · Quantitative Biology 2007-05-23 Miloje M. Rakocevic

This paper investigates a unification of distributed source coding, multiple description coding, and source coding with side information at decoders. The equivalence between the multiple-decoder extension of distributed source coding with…

Information Theory · Computer Science 2024-10-28 Jun Muramatsu

The tendencies described in this work were revealed in the course of examination of adenine and uracil distribution in the mRNA encoding sequence. The study also discusses the usage of codons occupied by the amino acid arginine in the table…

Other Quantitative Biology · Quantitative Biology 2009-08-11 Denis A. Semenov

Rooted trees with probabilities are used to analyze properties of a variable length code. A bound is derived on the difference between the entropy rates of the code and a memoryless source. The bound is in terms of normalized informational…

Information Theory · Computer Science 2013-10-11 Georg Böcherer , Rana Ali Amjad

Metacells are disjoint and homogeneous groups of single-cell profiles, representing discrete and highly granular cell states. Existing metacell algorithms tend to use only one modality to infer metacells, even though single-cell multi-omics…

Genomics · Quantitative Biology 2022-07-26 Haiyi Mao , Minxue Jia , Jason Xiaotian Dou , Haotian Zhang , Panayiotis V. Benos

Entropy measures of probability distributions are widely used measures in ecology, biology, genetics, and in other fields, to quantify species diversity of a community. Unfortunately, entropy-based diversity indices, or diversity indices…

Populations and Evolution · Quantitative Biology 2014-08-14 Karim T. Abou-Moustafa

In the crystal basis model of the genetic code, it is deduced that the sum of usage probabilities of the codons with C and A in the third position for the quartets and/or sextets is independent of the biological species for vertebrates. A…

Biological Physics · Physics 2009-11-07 L. Frappat , A. Sciarrino , P. Sorba

Just as in eukaryotes, high-throughput chromosome conformation capture (Hi-C) data have revealed nested organizations of bacterial chromosomes into overlapping interaction domains. In this chapter, we present a multiscale analysis framework…

Genomics · Quantitative Biology 2020-10-06 Nelle Varoquaux , Virginia S. Lioy , Frédéric Boccard , Ivan Junier

We present the use of single-cell entropy (scEntropy) to measure the order of the cellular transcriptome profile from single-cell RNA-seq data, which leads to a method of unsupervised cell type classification through scEntropy followed by…

Quantitative Methods · Quantitative Biology 2020-02-18 Jingxin Liu , You Song , Jinzhi Lei

Diffraction methods are used to detect atomic order in solids. While uniquely ergodic systems with pure point diffraction have zero entropy, the relation between diffraction and entropy is not as straightforward in general. In particular,…

Mathematical Physics · Physics 2012-05-08 Michael Baake , Uwe Grimm

We begin by reviewing some probabilistic results about the Dirichlet Process and its close relatives, focussing on their implications for statistical modelling and analysis. We then introduce a class of simple mixture models in which…

Methodology · Statistics 2010-03-23 Peter J. Green

Preserving biodiversity and ecosystem stability is a challenge that can be pursued through modern statistical mechanics modeling. Here we introduce a variational maximum entropy-based algorithm to evaluate the entropy in a minimal ecosystem…

Biological Physics · Physics 2018-10-17 Mattia Miotto , Lorenzo Monacelli

We establish a connection between barcode entropy and metric entropy. Namely, we show that the barcode entropy bounds the metric entropy from below for a measure from a specific class of invariant measures associated with a pair of…

Symplectic Geometry · Mathematics 2025-07-18 Erman Cineli , Viktor L. Ginzburg , Basak Z. Gurel

A novel principle is presented which allows for the proof of bounded weak solutions to a class of physically relevant, strongly coupled parabolic systems exhibiting a formal gradient-flow structure. The main feature of these systems is that…

Analysis of PDEs · Mathematics 2015-06-11 Ansgar Jüngel

Genomes may be analyzed from an information viewpoint as very long strings, containing functional elements of variable length, which have been assembled by evolution. In this work an innovative information theory based algorithm is…

Genomics · Quantitative Biology 2020-09-23 Vincenzo Bonnici , Giuditta Franco , Vincenzo Manca