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Deep research agents, which synthesize information across diverse sources, are significantly constrained by the sequential nature of reasoning. This bottleneck results in high latency, poor runtime adaptability, and inefficient resource…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-03-31 Lunyiu Nie , Nedim Lipka , Ryan A. Rossi , Swarat Chaudhuri

Drug discovery is the most expensive, time demanding and challenging project in biopharmaceutical companies which aims at the identification and optimization of lead compounds from large-sized chemical libraries. The lead compounds should…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-12-02 Natarajan Arul Murugan , Artur Podobas , Davide Gadioli , Emanuele Vitali , Gianluca Palermo , Stefano Markidis

Clustering multi-dimensional points is a fundamental task in many fields, and density-based clustering supports many applications as it can discover clusters of arbitrary shapes. This paper addresses the problem of Density-Peaks Clustering…

Databases · Computer Science 2022-12-01 Daichi Amagata , Takahiro Hara

We present MRPC, an R package that learns causal graphs with improved accuracy over existing packages, such as pcalg and bnlearn. Our algorithm builds on the powerful PC algorithm, the canonical algorithm in computer science for learning…

Machine Learning · Statistics 2018-06-07 Md. Bahadur Badsha , Evan A Martin , Audrey Qiuyan Fu

Multi-core machines are ubiquitous. However, most inductive logic programming (ILP) approaches use only a single core, which severely limits their scalability. To address this limitation, we introduce parallel techniques based on…

Artificial Intelligence · Computer Science 2021-09-16 Andrew Cropper , Oghenejokpeme Orhobor , Cristian Dinu , Rolf Morel

This work aims to improve the sample efficiency of parallel large-scale ranking and selection (R&S) problems by leveraging correlation information. We modify the commonly used "divide and conquer" framework in parallel computing by adding a…

Methodology · Statistics 2026-02-16 Zishi Zhang , Yijie Peng

Parallel computing is a standard approach to achieving high-performance computing (HPC). Three commonly used methods to implement parallel computing include: 1) applying multithreading technology on single-core or multi-core CPUs; 2)…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-09-18 Xinyao Yi

Analyzing time-series cross-sectional (also known as longitudinal or panel) data is an important process across a number of fields, including the social sciences, economics, finance, and medicine. PanelMatch is an R package that implements…

Methodology · Statistics 2025-08-19 Adam Rauh , In Song Kim , Kosuke Imai

Clustering multidimensional points is a fundamental data mining task, with applications in many fields, such as astronomy, neuroscience, bioinformatics, and computer vision. The goal of clustering algorithms is to group similar objects…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-05-22 Yihao Huang , Shangdi Yu , Julian Shun

Multi-core and highly-connected architectures have become ubiquitous, and this has brought renewed interest in language-based approaches to the exploitation of parallelism. Since its inception, logic programming has been recognized as a…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-01-25 Agostino Dovier , Andrea Formisano , Gopal Gupta , Manuel V. Hermenegildo , Enrico Pontelli , Ricardo Rocha

In this guide, we present how to perform constraint-based causal discovery using three popular software packages: pcalg (with add-ons tpc and micd), bnlearn, and TETRAD. We focus on how these packages can be used with observational data and…

Applications · Statistics 2023-12-20 Ryan M. Andrews , Ronja Foraita , Vanessa Didelez , Janine Witte

Local search is a successful approach for solving combinatorial optimization and constraint satisfaction problems. With the progressing move toward multi and many-core systems, GPUs and the quest for Exascale systems, parallelism has become…

Programming Languages · Computer Science 2013-05-13 Rui Machado , Salvador Abreu , Daniel Diaz

Correlation among the observations in high-dimensional regression modeling can be a major source of confounding. We present a new open-source package, plmmr, to implement penalized linear mixed models in R. This R package estimates…

Computation · Statistics 2026-05-13 Tabitha K. Peter , Anna C. Reisetter , Yujing Lu , Oscar A. Rysavy , Patrick J. Breheny

Parallelization techniques have become ubiquitous for accelerating inference and training of deep neural networks. Despite this, several operations are still performed in a sequential manner. For instance, the forward and backward passes…

Machine Learning · Computer Science 2023-10-30 Federico Danieli , Miguel Sarabia , Xavier Suau , Pau Rodríguez , Luca Zappella

High-Performance Computing (HPC) platforms enable scientific software to achieve breakthroughs in many research fields such as physics, biology, and chemistry, by employing Research Software Engineering (RSE) techniques. These include 1)…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-10-16 Matan Rusanovsky , Re'em Harel , Lee-or Alon , Idan Mosseri , Harel Levin , Gal Oren

A* is a best-first search algorithm for finding optimal-cost paths in graphs. A* benefits significantly from parallelism because in many applications, A* is limited by memory usage, so distributed memory implementations of A* that use all…

Artificial Intelligence · Computer Science 2017-08-18 Alex Fukunaga , Adi Botea , Yuu Jinnai , Akihiro Kishimoto

Large-scale observational health databases are increasingly popular for conducting comparative effectiveness and safety studies of medical products. However, increasing number of patients poses computational challenges when fitting survival…

Computation · Statistics 2023-10-26 Jianxiao Yang , Martijn J. Schuemie , Xiang Ji , Marc A. Suchard

Nowadays, we are to find out solutions to huge computing problems very rapidly. It brings the idea of parallel computing in which several machines or processors work cooperatively for computational tasks. In the past decades, there are a…

Programming Languages · Computer Science 2014-02-07 Brijender Kahanwal

Ensuring constraint satisfaction is a key requirement for safety-critical systems, which include most robotic platforms. For example, constraints can be used for modeling joint position/velocity/torque limits and collision avoidance.…

Robotics · Computer Science 2025-09-04 Elias Fontanari , Gianni Lunardi , Matteo Saveriano , Andrea Del Prete

We introduce the R package ContaminatedMixt, conceived to disseminate the use of mixtures of multivariate contaminated normal distributions as a tool for robust clustering and classification under the common assumption of elliptically…

Computation · Statistics 2016-06-14 Antonio Punzo , Angelo Mazza , Paul D. McNicholas