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KV-cache compression at small budgets is a crowded design space spanning cache representation, head-wise routing, compression cadence, decoding behavior, and within-budget scoring. We study seven mechanisms across these five families under…

Machine Learning · Computer Science 2026-05-19 Libo Sun , Po-wei Harn , Peixiong He , Xiao Qin

The prediction interval is gaining prominence in meta-analysis as it enables the assessment of uncertainties in treatment effects and heterogeneity between studies. However, coverage probabilities of the current standard method for…

Methodology · Statistics 2021-10-18 Kengo Nagashima , Hisashi Noma , Toshi A. Furukawa

Counting the frequencies of k-mers in read libraries is often a first step in the analysis of high-throughput sequencing experiments. Infrequent k-mers are assumed to be a result of sequencing errors. The frequent k-mers constitute a…

Genomics · Quantitative Biology 2013-05-09 Rajat Shuvro Roy , Debashish Bhattacharya , Alexander Schliep

Consistency-based methods have emerged as an effective approach to uncertainty quantification (UQ) in large language models. These methods typically rely on several generations obtained via multinomial sampling, measuring their agreement…

Particle production from secondary proton-proton collisions, commonly referred to as pile-up, impair the sensitivity of both new physics searches and precision measurements at LHC experiments. We propose a novel algorithm, PUMA, for…

Instrumentation and Detectors · Physics 2022-11-03 Benedikt Maier , Siddharth M. Narayanan , Gianfranco de Castro , Maxim Goncharov , Christoph Paus , Matthias Schott

Authors develop new nonparametric methods for verification and monitoring for quantum randomness based on the ranged correlation function (RCF) and a sequence of the ranged amplitudes (SRA). We carried out RCF-analysis of different topology…

Quantum Physics · Physics 2018-10-11 N. S. Perminov , O. I. Bannik , D. Yu. Tarankova , R. R. Nigmatullin

A natural measure for the amount of quantum information that a physical system E holds about another system A = A_1,...,A_n is given by the min-entropy Hmin(A|E). Specifically, the min-entropy measures the amount of entanglement between E…

Quantum Physics · Physics 2015-06-16 Frédéric Dupuis , Omar Fawzi , Stephanie Wehner

Summary: We describe a tool for quantifying the uniformity of mapped reads in high-throughput sequencing experiments. Our statistic directly measures the uniformity of both read position and fragment length, and we explain how to compute a…

Genomics · Quantitative Biology 2013-10-22 Valerie Hower , Richard Starfield , Adam Roberts , Lior Pachter

Context: Mining software repositories is a popular means to gain insights into a software project's evolution, monitor project health, support decisions and derive best practices. Tools supporting the mining process are commonly applied by…

Software Engineering · Computer Science 2025-11-13 Nicole Hoess , Carlos Paradis , Rick Kazman , Wolfgang Mauerer

Matrix approximations are a key element in large-scale algebraic machine learning approaches. The recently proposed method MEKA (Si et al., 2014) effectively employs two common assumptions in Hilbert spaces: the low-rank property of an…

Machine Learning · Computer Science 2022-01-21 Simon Heilig , Maximilian Münch , Frank-Michael Schleif

We present Kernel-QuantTree Exponentially Weighted Moving Average (KQT-EWMA), a non-parametric change-detection algorithm that combines the Kernel-QuantTree (KQT) histogram and the EWMA statistic to monitor multivariate data streams online.…

Machine Learning · Computer Science 2025-05-28 Michelangelo Olmo Nogara Notarianni , Filippo Leveni , Diego Stucchi , Luca Frittoli , Giacomo Boracchi

Objective: Quantitative real-time PCR is widely used for gene expression analysis, yet inconsistencies in data storage and reporting limit reproducibility. While MIQE guidelines define the minimal information required for publication, they…

Quantitative Methods · Quantitative Biology 2025-10-16 Mirco Castoldi

For taxonomic classification, we are asked to index the genomes in a phylogenetic tree such that later, given a DNA read, we can quickly choose a small subtree likely to contain the genome from which that read was drawn. Although popular…

Data Structures and Algorithms · Computer Science 2024-04-08 Dominika Draesslerová , Omar Ahmed , Travis Gagie , Jan Holub , Ben Langmead , Giovanni Manzini , Gonzalo Navarro

Frequent pattern mining is a flagship problem in data mining. In its most basic form, it asks for the set of substrings of a given string $S$ of length $n$ that occur at least $\tau$ times in $S$, for some integer $\tau\in[1,n]$. We…

Data Structures and Algorithms · Computer Science 2025-06-06 Pengxin Bian , Panagiotis Charalampopoulos , Lorraine A. K. Ayad , Manal Mohamed , Solon P. Pissis , Grigorios Loukides

Standard quantum inference converts quantum data into classical outputs. We study an alternative inference setting in which the desired output is quantum, preserving coherence. Such settings include quantum purity amplification (QPA),…

Quantum Physics · Physics 2026-05-21 Zhaoyi Li , Elias Theil , Aram W. Harrow , Isaac Chuang

K-mer abundance analysis is widely used for many purposes in nucleotide sequence analysis, including data preprocessing for de novo assembly, repeat detection, and sequencing coverage estimation. We present the khmer software package for…

Genomics · Quantitative Biology 2014-08-07 Qingpeng Zhang , Jason Pell , Rosangela Canino-Koning , Adina Chuang Howe , C. Titus Brown

Motivation: With the rapid expansion of large-scale biological datasets, DNA and protein sequence alignments have become essential for comparative genomics and proteomics. These alignments facilitate the exploration of sequence similarity…

Genomics · Quantitative Biology 2024-12-02 Michail Patsakis , Kimonas Provatas , Ioannis Mouratidis , Ilias Georgakopoulos-Soares

Mid-circuit measurement (MCM) provides the capability for qubit reuse and dynamic control in quantum processors, enabling more resource-efficient algorithms and supporting error-correction procedures. However, MCM introduces several sources…

Quantum Physics · Physics 2025-11-17 Ming Zhong , Zhemin Zhang , Xiangyu Ren , Chenghong Zhu , Siyuan Niu , Zhiding Liang

Large-scale scientific collaborations, such as the Compact Muon Solenoid (CMS) at CERN, produce a vast and ever-growing corpus of internal documentation. Navigating this complex information landscape presents a significant challenge for…

Information Retrieval · Computer Science 2026-03-12 Abhishikth Mallampalli , Sridhara Dasu

We present a short tutorial and introduction to using the R package TDA, which provides some tools for Topological Data Analysis. In particular, it includes implementations of functions that, given some data, provide topological information…

Mathematical Software · Computer Science 2015-01-30 Brittany Terese Fasy , Jisu Kim , Fabrizio Lecci , Clément Maria