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Despite deep convolutional neural networks boost the performance of image classification and segmentation in digital pathology analysis, they are usually weak in interpretability for clinical applications or require heavy annotations to…

Computer Vision and Pattern Recognition · Computer Science 2020-02-10 Yongxiang Huang , Albert C. S. Chung

Deep learning demands a huge amount of well-labeled data to train the network parameters. How to use the least amount of labeled data to obtain the desired classification accuracy is of great practical significance, because for many…

Machine Learning · Computer Science 2019-12-20 Xiao Han , Zihao Wang , Enmei Tu , Gunnam Suryanarayana , Jie Yang

In this paper we consider the problem of semi-supervised learning with deep Convolutional Neural Networks (ConvNets). Semi-supervised learning is motivated on the observation that unlabeled data is cheap and can be used to improve the…

Computer Vision and Pattern Recognition · Computer Science 2016-06-13 Mehdi Sajjadi , Mehran Javanmardi , Tolga Tasdizen

With the long-term rapid increase in incidences of colorectal cancer (CRC), there is an urgent clinical need to improve risk stratification. The conventional pathology report is usually limited to only a few histopathological features.…

Image and Video Processing · Electrical Eng. & Systems 2020-07-08 Christian Abbet , Inti Zlobec , Behzad Bozorgtabar , Jean-Philippe Thiran

Risk prediction models are widely used to guide real-world decision-making in areas such as healthcare and economics, and they also play a key role in estimating nuisance parameters in semiparametric inference. The super learner is a…

Methodology · Statistics 2025-09-05 Anders Munch , Thomas A. Gerds

Survival risk stratification is an important step in clinical decision making for breast cancer management. We propose a novel deep learning approach for this purpose by integrating histopathological imaging, genetic and clinical data. It…

Computer Vision and Pattern Recognition · Computer Science 2024-02-20 Raktim Kumar Mondol , Ewan K. A. Millar , Arcot Sowmya , Erik Meijering

Multiomics data fusion integrates diverse data modalities, ranging from transcriptomics to proteomics, to gain a comprehensive understanding of biological systems and enhance predictions on outcomes of interest related to disease phenotypes…

Quantitative Methods · Quantitative Biology 2023-08-04 Daisy Yi Ding , Xiaotao Shen , Michael Snyder , Robert Tibshirani

Semi-supervised learning (SSL) is a common approach to learning predictive models using not only labeled examples, but also unlabeled examples. While SSL for the simple tasks of classification and regression has received a lot of attention…

Machine Learning · Computer Science 2024-04-02 Jurica Levatić , Michelangelo Ceci , Dragi Kocev , Sašo Džeroski

Predicting drug response in patients from preclinical data remains a major challenge in precision oncology due to the substantial biological gap between in vitro cell lines and patient tumors. Rather than aiming to improve absolute in vitro…

Machine Learning · Computer Science 2026-03-18 Camille Jimenez Cortes , Philippe Lalanda , German Vega

In the 21st-century information age, with the development of big data technology, effectively extracting valuable information from massive data has become a key issue. Traditional data mining methods are inadequate when faced with…

Computer Vision and Pattern Recognition · Computer Science 2024-11-28 Aoran Shen , Minghao Dai , Jiacheng Hu , Yingbin Liang , Shiru Wang , Junliang Du

Semi-supervised learning deals with the problem of how, if possible, to take advantage of a huge amount of unclassified data, to perform a classification in situations when, typically, there is little labeled data. Even though this is not…

Machine Learning · Statistics 2020-12-11 Alejandro Cholaquidis , Ricardo Fraiman , Mariela Sued

Deep learning is the state-of-the-art for medical imaging tasks, but requires large, labeled datasets. For risk prediction, large datasets are rare since they require both imaging and follow-up (e.g., diagnosis codes). However, the release…

Image and Video Processing · Electrical Eng. & Systems 2023-06-16 Yanru Chen , Michael T Lu , Vineet K Raghu

Effective convolutional neural networks are trained on large sets of labeled data. However, creating large labeled datasets is a very costly and time-consuming task. Semi-supervised learning uses unlabeled data to train a model with higher…

Computer Vision and Pattern Recognition · Computer Science 2016-06-16 Mehdi Sajjadi , Mehran Javanmardi , Tolga Tasdizen

Early cancer detection is crucial for prognosis, but many cancer types lack large labelled datasets required for developing deep learning models. This paper investigates self-supervised learning (SSL) as an alternative to the standard…

Image and Video Processing · Electrical Eng. & Systems 2024-11-27 Hamish Haggerty , Rohitash Chandra

While making a tremendous impact in various fields, deep neural networks usually require large amounts of labeled data for training which are expensive to collect in many applications, especially in the medical domain. Unlabeled data, on…

Computer Vision and Pattern Recognition · Computer Science 2020-02-25 Yingda Xia , Fengze Liu , Dong Yang , Jinzheng Cai , Lequan Yu , Zhuotun Zhu , Daguang Xu , Alan Yuille , Holger Roth

Consistency learning plays a crucial role in semi-supervised medical image segmentation as it enables the effective utilization of limited annotated data while leveraging the abundance of unannotated data. The effectiveness and efficiency…

Computer Vision and Pattern Recognition · Computer Science 2023-05-26 Zhenxi Zhang , Ran Ran , Chunna Tian , Heng Zhou , Xin Li , Fan Yang , Zhicheng Jiao

Predicting phenotypes from gene expression data is a crucial task in biomedical research, enabling insights into disease mechanisms, drug responses, and personalized medicine. Traditional machine learning and deep learning rely on…

Machine Learning · Computer Science 2025-09-18 Kevin Dradjat , Massinissa Hamidi , Pierre Bartet , Blaise Hanczar

Semi-supervised machine learning models learn from a (small) set of labeled training examples, and a (large) set of unlabeled training examples. State-of-the-art models can reach within a few percentage points of fully-supervised training,…

Machine Learning · Computer Science 2021-08-11 Nicholas Carlini

Genomics are rapidly transforming medical practice and basic biomedical research, providing insights into disease mechanisms and improving therapeutic strategies, particularly in cancer. The ability to predict the future course of a…

Neural and Evolutionary Computing · Computer Science 2016-09-29 Safoora Yousefi , Congzheng Song , Nelson Nauata , Lee Cooper

When oncologists estimate cancer patient survival, they rely on multimodal data. Even though some multimodal deep learning methods have been proposed in the literature, the majority rely on having two or more independent networks that share…

Image and Video Processing · Electrical Eng. & Systems 2022-09-13 Numan Saeed , Ikboljon Sobirov , Roba Al Majzoub , Mohammad Yaqub