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The stochastic nature of chemical reactions involving randomly fluctuating population sizes has lead to a growing research interest in discrete-state stochastic models and their analysis. A widely-used approach is the description of the…

Quantitative Methods · Quantitative Biology 2015-10-01 Alexander Andreychenko , Luca Bortolussi , Ramon Grima , Philipp Thomas , Verena Wolf

It is generally recognized that a distinguishing feature of life is its peculiar capability to avoid equilibration. The origin of this capability and its evolution along the timeline of abiogenesis is not yet understood. We propose to study…

Molecular Networks · Quantitative Biology 2016-10-13 Dmitry Yu. Zubarev , Leonardo A. Pachón

Kinetics of conformational change of a semiflexible polymer under mechanical external field were investigated with Langevin dynamics simulations. It is found that a semiflexible polymer exhibits large hysteresis in mechanical…

Soft Condensed Matter · Physics 2009-11-10 Natsuhiko Yoshinaga , Kenichi Yoshikawa , Takao Ohta

Biomolecular folding, at least in simple systems, can be described as a two state transition in a free energy landscape with two deep wells separated by a high barrier. Transition paths are the short part of the trajectories that cross the…

Statistical Mechanics · Physics 2018-12-10 M. Laleman , E. Carlon , H. Orland

Optimizing the energy efficiency of driving processes provides valuable insights into the underlying physics and is of crucial importance for numerous applications, from biological processes to the design of machines and robots. Knowledge…

Soft Condensed Matter · Physics 2024-04-02 Sarah A. M. Loos , Samuel Monter , Felix Ginot , Clemens Bechinger

We review the generation of random pure states using a protocol of repeated two qubit gates. We study the dependence of the convergence to states with Haar multipartite entanglement distribution. We investigate the optimal generation of…

Quantum Physics · Physics 2009-01-26 A. Borras , A. Majtey , M. Casas

Motivated by recent nanofluidics experiments, we use Brownian dynamics and Monte Carlo simulations to study the conformation, organization and dynamics of two polymer chains confined to a single box-like cavity. The polymers are modeled as…

Soft Condensed Matter · Physics 2021-05-19 James M. Polson , Desiree A. Rehel

This study is devoted to the long-term behavior of nucleation, growth and fragmentation equations, modeling the spontaneous formation and kinetics of large polymers in a spatially homogeneous and closed environment. Such models are, for…

Analysis of PDEs · Mathematics 2018-11-20 Juan Calvo , Marie Doumic , Benoît Perthame

The onset of self-assembly in a dilute aqueous solution containing a flexible polymer and surfactant is theoretically studied. Focusing on the effect of the surfactant on polymer conformation and using a conjecture of partial collapse of…

Soft Condensed Matter · Physics 2007-05-23 Haim Diamant , David Andelman

Biological cells with all of their surface structure and complex interior stripped away are essentially vesicles - membranes composed of lipid bilayers which form closed sacs. Vesicles are thought to be relevant as models of primitive…

Statistical Mechanics · Physics 2015-05-18 Pietro de Anna , Francesca Di Patti , Duccio Fanelli , Alan J. McKane , Thierry Dauxois

Cells generally convert external nutrient resources to support metabolismand growth. Understanding the thermodynamic efficiency of this conversion is essential to determine the general characteristics of cellular growth. Using a simple…

Subcellular Processes · Quantitative Biology 2015-06-19 Yusuke Himeoka , Kunihiko Kaneko

In this paper we revisit the problem of a (non self-avoiding) polymer chain in a random medium which was previously investigated by Edwards and Muthukumar (EM). As noticed by Cates and Ball (CB) there is a discrepancy between the…

Disordered Systems and Neural Networks · Physics 2009-10-31 Yadin Y. Goldschmidt

We prove several limits on the behavior of a model of self-assembling particles introduced by Dabby and Chen (SODA 2013), called insertion systems, where monomers insert themselves into the middle of a growing linear polymer. First, we…

Data Structures and Algorithms · Computer Science 2015-10-29 Benjamin Hescott , Caleb Malchik , Andrew Winslow

We investigate the equilibration of an isolated macroscopic quantum system in the sense that deviations from a steady state become unmeasurably small for the overwhelming majority of times within any sufficiently large time interval. The…

Statistical Mechanics · Physics 2012-04-20 Peter Reimann , Michael Kastner

We study a class of random processes on $N$ particles which can be interpreted as stochastic model of luminescence. Each particle can stay in one of two states: Excited state or ground state. Any particle at ground state is excited with a…

Probability · Mathematics 2018-10-31 E. Pechersky , S. Pirogov , G. M. Schütz , A. Vladimirov , A. Yambartsev

The problem of estimating entropy production from incomplete information in stochastic thermodynamics is essential for theory and experiments. Whereas a considerable amount of work has been done on this topic, arguably, most of it is…

Statistical Mechanics · Physics 2024-12-17 Pedro E. Harunari , Carlos E. Fiore , Andre C. Barato

Wet-lab experiments, in which the dynamics within living cells are observed, are usually costly and time consuming. This is particularly true if single-cell measurements are obtained using experimental techniques such as flow-cytometry or…

Cell Behavior · Quantitative Biology 2014-12-18 Charalampos Kyriakopoulos , Verena Wolf

It is a long-standing question in origin-of-life research whether the information content of replicating molecules can be maintained in the presence of replication errors. Extending standard quasispecies models of non-enzymatic replication,…

Populations and Evolution · Quantitative Biology 2009-12-03 B. Obermayer , E. Frey

The notion of (auto) catalytic networks has become a cornerstone in understanding the possibility of a sudden dramatic increase of diversity in biological evolution as well as in the evolution of social and economical systems. Here we study…

Other Condensed Matter · Physics 2016-10-05 Rudolf Hanel , Stuart A. Kauffman , Stefan Thurner

We are concerned with the long time behavior of the stochastic Navier--Stokes system for compressible fluids in dimension two and three. In this setting, the part of the phase space occupied by the solution depends sensitively on the choice…

Analysis of PDEs · Mathematics 2020-12-15 Dominic Breit , Eduard Feireisl , Martina Hofmanova