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This paper presents a novel benchmarking framework Dyport for evaluating biomedical hypothesis generation systems. Utilizing curated datasets, our approach tests these systems under realistic conditions, enhancing the relevance of our…

Artificial Intelligence · Computer Science 2023-12-07 Ilya Tyagin , Ilya Safro

Apache Spark is a Big Data framework for working on large distributed datasets. Although widely used in the industry, it remains rather limited in the academic community or often restricted to software engineers. The goal of this paper is…

Instrumentation and Methods for Astrophysics · Physics 2019-07-17 S. Plaszczynski , J. Peloton , C. Arnault , J. E. Campagne

We present the Thought Graph as a novel framework to support complex reasoning and use gene set analysis as an example to uncover semantic relationships between biological processes. Our framework stands out for its ability to provide a…

Computation and Language · Computer Science 2024-03-13 Chi-Yang Hsu , Kyle Cox , Jiawei Xu , Zhen Tan , Tianhua Zhai , Mengzhou Hu , Dexter Pratt , Tianlong Chen , Ziniu Hu , Ying Ding

Machine learning classification problems are widespread in bioinformatics, but the technical knowledge required to perform model training, optimization, and inference can prevent researchers from utilizing this technology. This article…

Machine Learning · Computer Science 2023-10-06 Aaron D. Mullen , Samuel E. Armstrong , Jeff Talbert , V. K. Cody Bumgardner

BEFANA is a free and open-source software tool for ecological network analysis and visualisation. It is adapted to ecologists' needs and allows them to study the topology and dynamics of ecological networks as well as apply selected machine…

Quantitative Methods · Quantitative Biology 2026-03-12 Martin Marzidovšek , Vid Podpečan , Erminia Conti , Marko Debeljak , Christian Mulder

Many available formal verification methods have been shown to be instances of a unified Branch-and-Bound (BaB) formulation. We propose a novel machine learning framework that can be used for designing an effective branching strategy as well…

Machine Learning · Computer Science 2021-07-28 Florian Jaeckle , Jingyue Lu , M. Pawan Kumar

The establishment of links between data (e.g., patient records) and Web resources (e.g., literature) and the proper visualization of such discovered knowledge is still a challenge in most Life Science domains (e.g., biomedicine). In this…

Information Retrieval · Computer Science 2010-12-09 R. Berlanga , E. Jimenez-Ruiz , V. Nebot

Knowledge graphs are an increasingly common data structure for representing biomedical information. These knowledge graphs can easily represent heterogeneous types of information, and many algorithms and tools exist for querying and…

Provenance is a record that describes how entities, activities, and agents have influenced a piece of data; it is commonly represented as graphs with relevant labels on both their nodes and edges. With the growing adoption of provenance in…

Machine Learning · Computer Science 2021-09-16 David Kohan Marzagão , Trung Dong Huynh , Ayah Helal , Sean Baccas , Luc Moreau

Fine-grained, span-level human evaluation has emerged as a reliable and robust method for evaluating text generation tasks such as summarization, simplification, machine translation and news generation, and the derived annotations have been…

Computation and Language · Computer Science 2023-10-17 David Heineman , Yao Dou , Wei Xu

Consider a Bayesian inference problem where a variable of interest does not take values in a Euclidean space. These "non-standard" data structures are in reality fairly common. They are frequently used in problems involving latent discrete…

Scientific research communities are embracing AI-based solutions to target tractable scientific tasks and improve research workflows. However, the development and evaluation of such solutions are scattered across multiple disciplines. We…

Artificial Intelligence · Computer Science 2022-06-14 Yatao Li , Jianfeng Zhan

Online discussion threads are conversational cascades in the form of posted messages that can be generally found in social systems that comprise many-to-many interaction such as blogs, news aggregators or bulletin board systems. We propose…

Social and Information Networks · Computer Science 2012-04-19 Vicenç Gómez , Hilbert J. Kappen , Nelly Litvak , Andreas Kaltenbrunner

Current model testing work has mostly focused on creating test cases. Identifying what to test is a step that is largely ignored and poorly supported. We propose Weaver, an interactive tool that supports requirements elicitation for guiding…

Computation and Language · Computer Science 2023-10-17 Chenyang Yang , Rishabh Rustogi , Rachel Brower-Sinning , Grace A. Lewis , Christian Kästner , Tongshuang Wu

Workflow management systems allow the users to develop complex applications at a higher level, by orchestrating functional components without handling the implementation details. Although a wide range of workflow engines are developed in…

Distributed, Parallel, and Cluster Computing · Computer Science 2009-10-06 Alexandru Costan , Corina Stratan , Eliana-Dina Tirsa , Mugurel Ionut Andreica , Valentin Cristea

Multi-omics data offer unprecedented insights into complex biological systems, yet their high dimensionality, sparsity, and intricate interactions pose significant analytical challenges. Network-based approaches have advanced multi-omics…

Probabilistic programming is a rapidly developing programming paradigm which enables the formulation of Bayesian models as programs and the automation of posterior inference. It facilitates the development of models and conducting Bayesian…

Software Engineering · Computer Science 2025-10-31 Nathanael Nussbaumer , Markus Böck , Jürgen Cito

We present a novel system that automatically extracts and generates informative and descriptive sentences from the biomedical corpus and facilitates the efficient search for relational knowledge. Unlike previous search engines or…

Computation and Language · Computer Science 2023-10-19 Kerui Zhu , Jie Huang , Kevin Chen-Chuan Chang

The success of Deep Learning and its potential use in many safety-critical applications has motivated research on formal verification of Neural Network (NN) models. In this context, verification involves proving or disproving that an NN…

Machine Learning · Computer Science 2025-08-27 Rudy Bunel , Jingyue Lu , Ilker Turkaslan , Philip H. S. Torr , Pushmeet Kohli , M. Pawan Kumar

Summary Brain Predictability toolbox (BPt) represents a unified framework of machine learning (ML) tools designed to work with both tabulated data (in particular brain, psychiatric, behavioral, and physiological variables) and neuroimaging…

Machine Learning · Computer Science 2020-11-04 Sage Hahn , Dekang Yuan , Wesley Thompson , Max M Owens , Nicholas Allgaier , Hugh Garavan