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This work is concerned with the identifiability of metabolic parameters from multi-region measurement data in quantitative PET imaging. It shows that, for the frequently used two-tissue compartment model and under reasonable assumptions, it…

Optimization and Control · Mathematics 2023-05-29 Martin Holler , Erion Morina , Georg Schramm

Multivalent associative proteins with strong complementary interactions play a crucial role in phase separation of intracellular liquid condensates. We study the internal dynamics of such "bond-network" condensates comprised of two…

Soft Condensed Matter · Physics 2022-02-02 Pierre Ronceray , Yaojun Zhang , Xichong Liu , Ned S. Wingreen

The complexity of mathematical models describing respiratory mechanics has grown in recent years to integrate with cardiovascular models and incorporate nonlinear dynamics. However, additional model complexity has rarely been studied in the…

Tissues and Organs · Quantitative Biology 2020-01-17 Laura Ellwein Fix

We establish some quantitative concentration estimates for the empirical measure of many independent variables, in transportation distances. As an application, we provide some error bounds for particle simulations in a model mean field…

Probability · Mathematics 2013-09-19 Francois Bolley , Arnaud Guillin , Cedric Villani

Fatigue is a broad, multifactorial concept that includes the subjective perception of reduced physical and mental energy levels. It is also one of the key factors that strongly affect patients' health-related quality of life. To date, most…

Human-Computer Interaction · Computer Science 2021-08-10 Yang Bai , Yu Guan , Jian Qing Shi , Wan-Fai Ng

Exergy is a very important thermodynamic quantity in several fields such as economy, engineering, ecology and yet it has attracted little attention in pure physics. One of the main problems of the currently used definition of exergy is its…

Statistical Mechanics · Physics 2023-04-28 F. Becattini

We consider two approaches to study the spread of infectious diseases within a spatially structured population distributed in social clusters. According whether we consider only the population of infected individuals or both populations of…

Probability · Mathematics 2007-10-30 Lamia Belhadji

With the help of metadynamics it is possible to calculate efficiently the free energy of systems displaying high energy barriers as a function of few selected "collective variables". In doing this, the contribution of all the other degrees…

Statistical Mechanics · Physics 2009-11-13 Guido Tiana

Statistical models of Surface electromyography (sEMG) signals have several applications such as better understanding of sEMG signal generation, improved pattern recognition based control of wearable exoskeletons and prostheses, improving…

Signal Processing · Electrical Eng. & Systems 2023-01-16 Durgesh Kusuru , Anish C. Turlapaty , Mainak Thakur

The maximum entropy technique (MENT) is used to determine the distribution functions of physical values. MENT naturally combines required maximum entropy, the properties of a system and connection conditions in the form of restrictions…

High Energy Physics - Experiment · Physics 2007-05-23 B. Z. Belashev , M. K. Suleymanov

Dormancy is an essential strategy for microorganisms to cope with environmental stress. However, global ecosystem models typically ignore microbial dormancy, resulting in major model uncertainties. To facilitate the consideration of…

Quantitative Methods · Quantitative Biology 2014-02-20 Gangsheng Wang , Melanie A. Mayes , Lianhong Gu , Christopher W. Schadt

Compartmental models based on tracer mass balance are extensively used in clinical and pre-clinical nuclear medicine in order to obtain quantitative information on tracer metabolism in the biological tissue. This paper is the second of a…

Medical Physics · Physics 2018-09-14 Delbary Fabrice , Garbarino Sara

The understanding of the fundamental properties of the climate system has long benefitted from the use of simple numerical models able to parsimoniously represent the essential ingredients of its processes. Here we introduce a new model for…

Chaotic Dynamics · Physics 2020-11-16 Gabriele Vissio , Valerio Lucarini

This paper reviews opportunities for using electron microscopy in various gas atmospheres for the analysis and morpho-physiological modification of biological structures. The approaches that allow varying the gaseous phase content, as well…

Instrumentation and Detectors · Physics 2018-08-02 O. V. Gradov , M. A. Gradova

Despite more than 100 years of study, it is unclear if the movement of proteins inside the cell is best described as a mosh pit or an exquisitely choreographed dance. Recent studies suggest the latter. Local interactions induce molecular…

Quantitative Methods · Quantitative Biology 2023-08-25 James A. Galbraith , Catherine G. Galbraith

We combine power-meter measurements with GPS measurements to study the model that accounts for the use of power by a cyclist. The model takes into account the change in elevation and speed along with adverse effects of air, rolling and…

Popular Physics · Physics 2021-03-18 Tomasz Danek , Michael A. Slawinski , Theodore Stanoev

The metabolic processes complexity is at the heart of energy conversion in living organisms and forms a huge obstacle to develop tractable thermodynamic metabolism models. By raising our analysis to a higher level of abstraction, we develop…

Statistical Mechanics · Physics 2020-06-02 C. Goupil , H. Ouerdane , E. Herbert , Y. D'Angelo , C. Goupil

The success of metabolomics studies depends upon the "fitness" of each biological sample used for analysis: it is critical that metabolite levels reported for a biological sample represent an accurate snapshot of the studied organism's…

Quantitative Methods · Quantitative Biology 2015-06-16 Barry M. Slaff , Shane T. Jensen , Aalim M. Weljie

Most three dimensional constitutive relations that have been developed to describe the behavior of bodies are correlated against one dimensional and two dimensional experiments. What is usually lost sight of is the fact that infinity of…

Numerical Analysis · Computer Science 2010-07-23 Satish Karra , K. R. Rajagopal

The use of the osmotic thermodynamic model, combined with a series of methane and carbon dioxide gas adsorption experiments at various temperatures, has allowed shedding some new light on the fascinating phase behavior of flexible…

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