Related papers: Numerical study of variable lung ventilation strat…
Background: Recent pandemic has brought a sudden surge in the requirement of mechanical ventilators all over the world. In this backdrop, there is wide interest in looking for ways to support multiple patients from a single ventilator.…
Mechanical ventilators sustain life of patients that are unable to breathe (sufficiently) on their own. The aim of this paper is to improve pressure tracking performance of mechanical ventilators for a wide variety of sedated patients. This…
We propose a multi-scale lung model to investigate spatio-temporal distributions of ventilation variables. Lung envelope and large airway geometries are derived from CT scans; smaller airways are generated using a physiologically consistent…
We consider the problem of controlling an invasive mechanical ventilator for pressure-controlled ventilation: a controller must let air in and out of a sedated patient's lungs according to a trajectory of airway pressures specified by a…
Mechanical ventilation is critical for managing respiratory failure, but inappropriate ventilator settings can lead to ventilator-induced lung injury (VILI), increasing patient morbidity and mortality. Evaluating the causal impact of…
Mechanical ventilation is one of the most widely used therapies in the ICU. However, despite broad application from anaesthesia to COVID-related life support, many injurious challenges remain. We frame these as a control problem:…
The choice of lung protective ventilation settings for mechanical ventilation has a considerable impact on patient outcome, yet identifying optimal ventilatory settings for individual patients remains highly challenging due to the inherent…
Naturally ventilated buildings harness freely-available resources such as internal buoyancy gains and wind forcing in achieving comfortable interior conditions. Although these resources are free, they are time-variable and can be difficult…
In the COVID-19 period, the number of deaths has increased every day around the world. The pandemic has impacted the life and economy. Especially, there is a shortage in medical including a lack of technology, facility and equipment. One of…
Uniform fluid flow distribution in a symmetric volume can be realized through a symmetric branched tree. It is shown here, however, that the flow partitioning can be highly sensitive to deviations from exact symmetry if inertial effects are…
The mammalian ventilatory behavior exhibits nonlinear dynamics as reflected by certain nonlinearity or complexity indicators (e.g. correlation dimension, approximate entropy, Lyapunov exponents...) but this is not sufficient to determine…
Objectives: The main objective of this review article is to evaluate the usability of Computational Fluid Dynamics (CFD) as a supporting clinical tool for respiratory system. Data Source: The English articles referred for this review paper…
We present a new approach for physics-based computational modeling of diseased human lungs. Our main object is the development of a model that takes the novel step of incorporating the dynamics of airway recruitment/de-recruitment into an…
This paper presents a recurrent neural network approach to simulating mechanical ventilator pressure. The traditional mechanical ventilator has a control pressure that is monitored by a medical practitioner and can behave incorrectly if the…
Natural ventilation can play an important role towards preventing the spread of airborne diseases in indoor environments. However, quantifying natural ventilation flow rates is a challenging task due to significant variability in the…
To mitigate the SARS-CoV-2 pandemic, officials have employed social distancing and stay-at-home measures, with increased attention to room ventilation emerging only more recently. Effective distancing practices for open spaces can be…
We study a linear inviscid model of a passively flexible swimmer with distributed flexibility, calculating its propulsive performance and optimal distributions of flexibility. The frequencies of actuation and mean stiffness ratios we…
This paper considers the control design for a low-cost ventilator that is based on a manual resuscitator bag (also known as AmbuBag) to pump air into the lungs of a patient who is physically unable to breathe. First, it experimentally shows…
An analysis of the general concept of volume variation partition of a porous body is presented, introducing the breathing coefficient, defined as the ratio of two volume variations. Considering a total volume of a porous body, composed of…
We show that enhanced turbulent mixing can be used to mitigate airborne COVID-19 transmission by dispersing virus-laden clouds in enclosed, poorly ventilated spaces. A simple system of fan-driven turbulent jets is designed so as to minimize…