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We study a totally asymmetric simple exclusion process equipped with Langmuir kinetics with boundaries connected to a common reservoir. The total number of particles in the system is conserved and controlled by filling factor $\mu$.…

Statistical Mechanics · Physics 2021-11-17 Bipasha Pal , Arvind Kumar Gupta

The traffic of molecular motors which interact through mutual exclusion is studied theoretically for half-open tube-like compartments. These half-open tubes mimic the shapes of axons. The mutual exclusion leads to traffic jams or density…

Statistical Mechanics · Physics 2007-05-23 Melanie J. I. Muller , Stefan Klumpp , Reinhard Lipowsky

Many biological processes are supported by special molecules, called motor proteins or molecular motors, that transport cellular cargoes along linear protein filaments and can reversibly associate to their tracks. Stimulated by these…

Statistical Mechanics · Physics 2021-11-17 Akriti Jindal , Anatoly B. Kolomeisky , Arvind Kumar Gupta

Enzymatic molecules that actively support many cellular processes, including transport, cell division and cell motility, are known as motor proteins or molecular motors. Experimental studies indicate that they interact with each other and…

Biological Physics · Physics 2015-05-20 Daniel Celis-Garza , Hamid Teimouri , Anatoly B. Kolomeisky

We study a model of aggregation and fragmentation of clusters of particles on an open segment of a single-lane road. The particles and clusters obey the stochastic discrete-time discrete-space kinetics of the Totally Asymmetric Simple…

Statistical Mechanics · Physics 2020-01-08 N. C. Pesheva , N. Zh. Bunzarova

The traffic of molecular motors through open tube-like compartments is studied using lattice models. These models exhibit boundary-induced phase transitions related to those of the asymmetric simple exclusion process (ASEP) in one…

Statistical Mechanics · Physics 2007-05-23 Stefan Klumpp , Reinhard Lipowsky

Theoretical advances in the study of non-equilibrium phenomena are briefly reviewed with emphasis on steady state properties of one-dimensional driven lattice gases. The presentation is focused on the totally asymmetric simple-exclusion…

Statistical Mechanics · Physics 2008-03-19 J. G. Brankov , N. C. Pesheva , N. Zh. Bunzarova

Biopolymers serve as one-dimensional tracks on which motor proteins move to perform their biological roles. Motor protein phenomena have inspired theoretical models of one-dimensional transport, crowding, and jamming. Experiments studying…

Biological Physics · Physics 2016-05-25 Hui-Shun Kuan , M. D. Betterton

Cytoskeletal motors known as motor proteins are molecules that drive cellular transport along several parallel cytoskeletal filaments and support many biological processes. Experimental evidences suggest that they interact with the nearest…

Statistical Mechanics · Physics 2017-11-22 Tripti Midha , A. K. Gupta

The effect of interactions on dynamics of coupled motor proteins is investigated theoretically. A simple stochastic discrete model, that allows to calculate explicitly the dynamic properties of the system, is developed. It is shown that…

Soft Condensed Matter · Physics 2009-11-11 Evgeny B. Stukalin , Anatoly B. Kolomeisky

The asymmetric simple exclusion process with additional Langmuir kinetics, i.e. attachment and detachment in the bulk, is a paradigmatic model for intracellular transport. Here we study this model in the presence of randomly distributed…

Statistical Mechanics · Physics 2009-11-13 Philip Greulich , Andreas Schadschneider

A system consisting of two parallel coupled channels where particles in one of them follow the rules of totally asymmetric exclusion processes (TASEP) and in another one move as in symmetric simple exclusion processes (SSEP) is investigated…

Statistical Mechanics · Physics 2009-11-13 K. Tsekouras , A. B. Kolomeisky

We report here results on the study of the totally asymmetric simple exclusion processes (TASEP), defined on an open network, consisting of head and tail simple chain segments with a double-chain section inserted in-between. Results of…

Statistical Mechanics · Physics 2013-06-19 Nina Pesheva , Jordan Brankov

We study the motion of kinks in a two-lane model of the totally asymmetric simple exclusion process with open boundaries. We analytically study the motion of the kinks by a decoupling approximation. In terms of the decoupling approximation,…

Statistical Mechanics · Physics 2007-05-23 Tetsuya Mitsudo , Hisao Hayakawa

In cells, most of cargos are transported by motor proteins along microtubule. Biophysically, unidirectional motion of large number of motor proteins along a single track can be described by totally asymmetric simple exclusion process…

Subcellular Processes · Quantitative Biology 2015-03-06 Minghua Song , Yunxin Zhang

Asymmetric exclusion processes for particles moving on parallel channels with inhomogeneous coupling are investigated theoretically. Particles interact with hard-core exclusion and move in the same direction on both lattices, while…

Statistical Mechanics · Physics 2009-11-13 K. Tsekouras , A. B. Kolomeisky

Motivated by experimental results on the interplay between molecular motors and tau proteins, we extend lattice-based models of intracellular transport to include a second species of particle which locally influences the motor-filament…

Subcellular Processes · Quantitative Biology 2010-04-27 H. Grzeschik , R. J. Harris , L. Santen

We propose an extension of the totally asymmetric simple exclusion process (TASEP) in which particles hopping along a lattice can be blocked by obstacles that dynamically attach/detach from lattice sites. The model can be thought as TASEP…

Statistical Mechanics · Physics 2019-02-20 Bartlomiej Waclaw , Justyna Cholewa-Waclaw , Philip Greulich

Motor proteins are active enzymatic molecules that drive a variety of biological processes, including transfer of genetic information, cellular transport, cell motility and muscles contraction. It is known that these biological molecular…

Soft Condensed Matter · Physics 2018-01-17 Luiza V. F. Gomes , Anatoly B. Kolomeisky

Totally asymmetric simple exclusion processes (TASEP) with particles which occupy more than one lattice site and with a local inhomogeneity far away from the boundaries are investigated. These non-equilibrium processes are relevant for the…

Statistical Mechanics · Physics 2009-11-10 Leah B. Shaw , Anatoly B. Kolomeisky , Kelvin H. Lee