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Bayesian Image-on-Scalar Regression (ISR) provides flexible, uncertainty-aware neuroimaging analysis. However, applying ISR to large-scale datasets such as the UK Biobank is challenging due to intensive computational demands and the need to…

Applications · Statistics 2026-02-09 Yuliang Xu , Timothy D. Johnson , Thomas E. Nichols , Jian Kang

In this article, we propose a novel spatial global-local spike-and-slab selection prior for image-on-scalar regression. We consider a Bayesian hierarchical Gaussian process model for image smoothing, that uses a flexible Inverse-Wishart…

Methodology · Statistics 2022-12-19 Zijian Zeng , Meng Li , Marina Vannucci

In neuroimaging studies, it becomes increasingly important to study associations between different imaging modalities using image-on-image regression (IIR), which faces challenges in interpretation, statistical inference, and prediction.…

Applications · Statistics 2026-03-24 Guoxuan Ma , Bangyao Zhao , Hasan Abu-Amara , Jian Kang

Scalar-on-image regression aims to investigate changes in a scalar response of interest based on high-dimensional imaging data. We propose a novel Bayesian nonparametric scalar-on-image regression model that utilises the spatial coordinates…

Methodology · Statistics 2022-06-23 Mica Teo Shu Xian , Sara Wade

Statistical modeling of fMRI data is challenging as the data are both spatially and temporally correlated. Spatially, measurements are taken at thousands of contiguous regions, called voxels, and temporally measurements are taken at…

Computation · Statistics 2017-10-05 Ming Teng , Farouk S. Nathoo , Timothy D. Johnson

In addressing the challenge of analysing the large-scale Adolescent Brain Cognition Development (ABCD) fMRI dataset, involving over 5,000 subjects and extensive neuroimaging data, we propose a scalable Bayesian scalar-on-image regression…

Methodology · Statistics 2024-03-21 Anna Menacher , Thomas E. Nichols , Timothy D. Johnson , Jian Kang

Spatial whole-brain Bayesian modeling of task-related functional magnetic resonance imaging (fMRI) is a great computational challenge. Most of the currently proposed methods therefore do inference in subregions of the brain separately or do…

Computation · Statistics 2017-01-03 Per Sidén , Anders Eklund , David Bolin , Mattias Villani

We propose a method that combines signals from many brain regions observed in functional Magnetic Resonance Imaging (fMRI) to predict the subject's behavior during a scanning session. Such predictions suffer from the huge number of brain…

Computer Vision and Pattern Recognition · Computer Science 2011-04-29 Vincent Michel , Alexandre Gramfort , Gaël Varoquaux , Evelyn Eger , Christine Keribin , Bertrand Thirion

This thesis is dedicated to the statistical analysis of multi-sub ject fMRI data, with the purpose of identifying bain structures involved in certain cognitive or sensori-motor tasks, in a reproducible way across sub jects. To overcome…

Applications · Statistics 2010-05-19 Merlin Keller , Alexis Roche , Marc Lavielle

Bayesian whole-brain functional magnetic resonance imaging (fMRI) analysis with three-dimensional spatial smoothing priors has been shown to produce state-of-the-art activity maps without pre-smoothing the data. The proposed inference…

Methodology · Statistics 2020-10-02 Per Sidén , Finn Lindgren , David Bolin , Anders Eklund , Mattias Villani

In recent years, Bayesian statistics methods in neuroscience have been showing important advances. In particular, detection of brain signals for studying the complexity of the brain is an active area of research. Functional magnetic…

Methodology · Statistics 2017-06-06 Jairo Alberto Fuquene Patiño , Brenda Betancourt , João B. M. Pereira

Detecting shared neural activity from functional magnetic resonance imaging (fMRI) across individuals exposed to the same stimulus can reveal synchronous brain responses, functional roles of regions, and potential clinical biomarkers.…

Applications · Statistics 2026-04-24 Spencer Wadsworth , Nabin Koirala , Nicole Landi , Ofer Harel

Neuroradiologists and neurosurgeons increasingly opt to use functional magnetic resonance imaging (fMRI) to map functionally relevant brain regions for noninvasive presurgical planning and intraoperative neuronavigation. This application…

Methodology · Statistics 2023-06-07 Andrew S. Whiteman , Andreas J. Bartsch , Jian Kang , Timothy D. Johnson

Feature selection, identifying a subset of variables that are relevant for predicting a response, is an important and challenging component of many methods in statistics and machine learning. Feature selection is especially difficult and…

Quantitative Methods · Quantitative Biology 2014-08-01 Charles K. Fisher , Pankaj Mehta

In recent years, Ising prior with the network information for the "in" or "out" binary random variable in Bayesian variable selections has received more and more attentions. In this paper, we discover that even without the informative prior…

Methodology · Statistics 2012-06-14 Zaili Fang , Inyoung Kim

In this paper, we develop a novel spatial variable selection method for scalar on vector-valued image regression in a multi-group setting. Here, 'vector-valued image' refers to the imaging datasets that contain vector-valued information at…

Methodology · Statistics 2024-10-22 Arkaprava Roy , Zhou Lan

The focus of this work is on spatial variable selection for scalar-on-image regression. We propose a new class of Bayesian nonparametric models, soft-thresholded Gaussian processes and develop the efficient posterior computation algorithms.…

Methodology · Statistics 2016-04-13 Jian Kang , Brian J. Reich , Ana-Maria Staicu

Autism spectrum disorder (ASD) is a complex neurodevelopmental syndrome. Early diagnosis and precise treatment are essential for ASD patients. Although researchers have built many analytical models, there has been limited progress in…

Neurons and Cognition · Quantitative Biology 2018-10-30 Juntang Zhuang , Nicha C. Dvornek , Xiaoxiao Li , Pamela Ventola , James S. Duncan

Inverse inference, or "brain reading", is a recent paradigm for analyzing functional magnetic resonance imaging (fMRI) data, based on pattern recognition and statistical learning. By predicting some cognitive variables related to brain…

This article is motivated by studying multisensory effects on brain activities in intracranial electroencephalography (iEEG) experiments. Differential brain activities to multisensory stimulus presentations are zero in most regions and…

Methodology · Statistics 2022-06-01 Zhengjia Wang , John Magnotti , Michael S. Beauchamp , Meng Li
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