Related papers: A coupled surface-Cahn--Hilliard bulk-diffusion sy…
Multicomponent lipid mixtures exhibit complex phase behavior, including coexistence of nanoscopic fluid phases in ternary mixtures mimicking the composition of the outer leaflet of mammalian plasma membrane. The physical mechanisms…
We extend the lipid-structured model for atherosclerotic plaque development of Ford et al. (2019) to account for macrophage proliferation. Proliferation is modelled as a non-local decrease in the lipid structural variable that is similar to…
We discuss the dynamics of a bilayer membrane with partial slip boundary conditions between the monolayers and the bulk fluid. Using Onsager's variational principle to account for the associated dissipations, we derive the coupled dynamic…
Electrochemical phenomena in biology often unfold in confined geometries where micrometer- to millimeter-scale domains coexist with nanometer-scale interfacial diffuse charge layers. We analyze a model lipid membrane-electrolyte system…
Vesicle fusion is an important process underlying cell division, transport, and membrane trafficking. In phospholipid systems, a range of fusogens including divalent cations and depletants have been shown to induce adhesion, hemifusion, and…
Using basic thermodynamic principles we derive a Cahn--Hilliard--Darcy model for tumour growth including nutrient diffusion, chemotaxis, active transport, adhesion, apoptosis and proliferation. The model generalises earlier models and in…
We investigate the large time behavior of an agent based model describing tumor growth. The microscopic model combines short-range repulsion and cell division. As the number of cells increases exponentially in time, the microscopic model is…
We investigate a new diffuse-interface model that describes creeping two-phase flows (i.e., flows exhibiting a low Reynolds number), especially flows that permeate a porous medium. The system of equations consists of a Brinkman equation for…
This paper presents a model and numerical analysis (simulations) of transmembrane potential induced in biological cell membrane under the influence of externally applied electric field (i.e., electroporation). This model differs from the…
The kinetics of droplet and bridge formation within striped nano-capillaries is studied when the wetting film grows via interface-limited growth. The phenomenological time-dependent Ginzburg-Landau (TDGL)-type model with thermal noise is…
In this paper we present a mathematical model to describe the phenomenon of phase separation, which is modelled as space regions where an order parameter changes smoothly. The model proposed, including thermal and mixing effects, is deduced…
A hybrid stochastic individual-based model of proliferating cells with chemotaxis is presented. The model is expressed by a branching diffusion process coupled to a partial differential equation describing concentration of a chemotactic…
The supramolecular assembly of lipids into bilayer membranes is essential for cellular structure and function. However, the impact of lipid structural variations such as acyl chain length, degree of unsaturation, and headgroup type on…
This paper presents a novel methodology for the direct numerical modeling and simulation of turbulent flows. The kinetic model equation is firstly extended to turbulent flow with the account of coupled evolution of kinetic, thermal, and…
We consider a computational model for complex-fluid-solid interaction based on a diffuse-interface model for the complex fluid and a hyperelastic-material model for the solid. The diffuse-interface complex-fluid model is described by the…
We consider two-layers of immiscible liquids confined between an upper and a lower rigid plate. The dynamics of the free liquid-liquid interface is described for arbitrary amplitudes by a single evolution equation derived from the basic…
We use a lattice Boltzmann method to study pattern formation in chemically reactive binary fluids in the regime where hydrodynamic effects are important. The coupled equations solved by the method are a Cahn-Hilliard equation, modified by…
We introduce a nonisothermal phase-field system of Caginalp type that describes tumor growth under hyperthermia. The model couples a possibly viscous Cahn-Hilliard equation, governing the evolution of the healthy and tumor phases, with an…
The process of phase separation of binary systems is described by the Cahn-Hilliard equation. The main objective of this article is to give a classification on the dynamic phase transitions for binary systems using either the classical…
We consider a phase-field system modelling solid tumour growth. This system consists of a Cahn-Hilliard equation coupled with a nutrient equation. The former is characterised by a degenerate mobility and a singular potential. Both equations…