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Lipid rafts are heterogeneous dynamic lipid domains of the cell membranes that are involved in several biological processes, like protein and lipids specific transport and signaling. Our understanding of lipid raft formation is still…

The Cahn--Hilliard equation is one of the most common models to describe phase separation processes of a mixture of two materials. For a better description of short-range interactions between the material and the boundary, various dynamic…

Analysis of PDEs · Mathematics 2021-04-27 Patrik Knopf , Kei Fong Lam , Chun Liu , Stefan Metzger

The present work is devoted to the modelling which is based on the modified Cahn-Hilliard equation, the interplay of equilibrium and non-equilibrium phase transitions. The non-equilibrium phase transitions are modelled by the Schl\"ogl…

Statistical Mechanics · Physics 2021-01-20 P. O. Mchedlov-Petrosyan , L. N. Davydov

Problems for partial differential equations coupled with dynamic boundary conditions can be viewed as a type of transmission problem between the bulk and its boundary. For the heat equation and the Allen-Cahn equation, various forms of such…

Analysis of PDEs · Mathematics 2025-08-06 Pierluigi Colli , Takeshi Fukao

A model of lipid bilayers made of a mixture of two lipids with different average compositions on both leaflets, is developed. A Landau hamiltonian describing the lipid-lipid interactions on each leaflet, with two lipidic fields $\psi_1$ and…

Soft Condensed Matter · Physics 2014-08-28 Guillaume Gueguen , Nicolas Destainville , Manoel Manghi

We study a Cahn--Hilliard two-phase model describing the flow of two viscoelastoplastic fluids, which arises in geodynamics. A phase-field variable indicates the proportional distribution of the two fluids in the mixture. The motion of the…

Analysis of PDEs · Mathematics 2025-10-01 Fan Cheng , Robert Lasarzik , Marita Thomas

We provide a detailed mathematical analysis of a model for phase separation on biological membranes which was recently proposed by Garcke, R\"atz, R\"oger and the second author. The model is an extended Cahn-Hilliard equation which contains…

Analysis of PDEs · Mathematics 2019-02-06 Helmut Abels , Johannes Kampmann

Random lateral translocation of lipids and proteins is a universal process on membrane surfaces. Local aggregation or organization of lipids and proteins can be induced when this lateral random diffusion is mediated by the electrostatic…

Quantitative Methods · Quantitative Biology 2015-06-03 Y. C. Zhou

We propose a model describing liquid-solid phase coexistence in mixed lipid membranes by including explicitly the occurrence of a rippled phase. For a single component membrane, we employ a previous model in which the membrane thickness is…

Soft Condensed Matter · Physics 2012-01-31 N. Shimokawa , S. Komura , D. Andelman

Biomembranes and vesicles consisting of multiple phases can attain a multitude of shapes, undergoing complex shape transitions. We study a Cahn--Hilliard model on an evolving hypersurface coupled to Navier--Stokes equations on the surface…

Numerical Analysis · Mathematics 2019-11-01 John W. Barrett , Harald Garcke , Robert Nürnberg

We consider two-phase fluid deformable surfaces as model systems for biomembranes. Such surfaces are modeled by incompressible surface Navier-Stokes-Cahn-Hilliard-like equations with bending forces. We derive this model using the…

Numerical Analysis · Mathematics 2023-08-03 Elena Bachini , Veit Krause , Ingo Nitschke , Axel Voigt

We show short-time well-posedness of a diffuse interface model describing the flow of a fluid through a deformable porous medium consisting of two phases. The system non-linearly couples Biot's equations for poroelasticity, including…

Analysis of PDEs · Mathematics 2026-05-01 Helmut Abels , Jonas Haselböck

Rafts, or functional domains, are transient nano- or mesoscopic structures in the plasma membrane and are thought to be essential for many cellular processes such as signal transduction, adhesion, trafficking and lipid/protein sorting.…

An asymptotic analysis for a system with equation and dynamic boundary condition of Cahn-Hilliard type is carried out as the coefficient of the surface diffusion acting on the phase variable tends to 0, thus obtaining a forward-backward…

Analysis of PDEs · Mathematics 2021-06-03 Pierluigi Colli , Takeshi Fukao , Luca Scarpa

We present a dynamical model of lipoprotein metabolism derived by combining a cascading process in the blood stream and cellular level regulatory dynamics. We analyse the existence and stability of equilibria and show that this…

Quantitative Methods · Quantitative Biology 2007-05-23 Elias August , Kim H. Parker , Mauricio Barahona

Recently we considered a stochastic discrete model which describes fronts of cells invading a wound \cite{KSS}. In the model cells can move, proliferate, and experience cell-cell adhesion. In this work we focus on a continuum description of…

Statistical Mechanics · Physics 2009-11-13 Evgeniy Khain , Leonard M. Sander

Motivated by the experimental study of Tayebi et al. [Nature Mater. 11, 1074 (2012)] on phase separation of stacked multi-component lipid bilayers, we propose a model composed of stacked two-dimensional Ising spins. We study both its static…

Soft Condensed Matter · Physics 2015-12-14 T. Hoshino , S. Komura , D. Andelman

The study of interactions between biomimetic membranes and micron-sized particles is crucial for understanding various biological processes. Here, we control microparticle spontaneous engulfment by giant lipid vesicles by tuning particle…

Soft Condensed Matter · Physics 2025-01-22 Clément Marque , Gaetano D'Avino , Domenico Larobina , Aude Michel , Ali Abou-Hassan , Antonio Stocco

We consider phase-field models with and without lateral flow for the numerical simulation of lateral phase separation and coarsening in lipid membranes. For the numerical solution of these models, we apply an unfitted finite element method…

Numerical Analysis · Mathematics 2023-06-02 Maxim Olshanskii , Yerbol Palzhanov , Annalisa Quaini

We consider coarsening dynamics associated with a Burgers--Cahn--Hilliard system modeling a two-phase flow in one space dimension. Our emphasis is on the effect that coupling between the phase and fluid dynamics has on coarsening rates, and…

Analysis of PDEs · Mathematics 2024-05-21 Peter Howard , Adam Larios , Quyuan Lin