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Many analyses of functional magnetic resonance imaging (fMRI) examine functional connectivity (FC), or the statistical dependencies among distant brain regions. These analyses are typically exploratory, guiding future confirmatory research.…

Applications · Statistics 2025-10-20 Kyle Stanley , Nicole Lazar , Matthew Reimherr

In many longitudinal settings, time-varying covariates may not be measured at the same time as responses and are often prone to measurement error. Naive last-observation-carried-forward methods incur estimation biases, and existing…

Methodology · Statistics 2023-03-10 Xinyue Chang , Yehua Li , Yi Li

In this work, we consider a multivariate regression model with one-sided errors. We assume for the regression function to lie in a general H\"{o}lder class and estimate it via a nonparametric local polynomial approach that consists of…

Statistics Theory · Mathematics 2021-02-11 Leonie Selk , Charles Tillier , Orlando Marigliano

Functional principal component analysis has become the most important dimension reduction technique in functional data analysis. Based on B-spline approximation, functional principal components (FPCs) can be efficiently estimated by the…

Methodology · Statistics 2022-11-10 Shiyuan He , Hanxuan Ye , Kejun He

Principal component analysis (PCA) is often used for analyzing data in the most diverse areas. In this work, we report an integrated approach to several theoretical and practical aspects of PCA. We start by providing, in an intuitive and…

Computational Engineering, Finance, and Science · Computer Science 2021-06-09 Felipe L. Gewers , Gustavo R. Ferreira , Henrique F. de Arruda , Filipi N. Silva , Cesar H. Comin , Diego R. Amancio , Luciano da F. Costa

We propose a Bayesian modeling framework for jointly analyzing multiple functional responses of different types (e.g. binary and continuous data). Our approach is based on a multivariate latent Gaussian process and models the dependence…

Methodology · Statistics 2016-01-12 Beth A. Tidemann-Miller , Brian J. Reich , Ana-Maria Staicu

Personalized treatment of patients based on tissue-specific cancer subtypes has strongly increased the efficacy of the chosen therapies. Even though the amount of data measured for cancer patients has increased over the last years, most…

Machine Learning · Statistics 2017-09-18 Nora K. Speicher , Nico Pfeifer

Between 2011 and 2014 NHANES collected objectively measured physical activity data using wrist-worn accelerometers for tens of thousands of individuals for up to seven days. In this study, we analyze minute-level indicators of being active,…

Methodology · Statistics 2025-04-01 Xinkai Zhou , Julia Wrobel , Ciprian M. Crainiceanu , Andrew Leroux

Multi-sensor data that track system operating behaviors are widely available nowadays from various engineering systems. Measurements from each sensor over time form a curve and can be viewed as functional data. Clustering of these…

Methodology · Statistics 2024-01-08 Zhongnan Jin , Jie Min , Yili Hong , Pang Du , Qingyu Yang

Multivariate functional data has received considerable attention but testing for equality of mean surfaces and its profile has limited progress. The existing literature has tested equality of either mean curves of univariate functional…

Methodology · Statistics 2019-03-07 Jin Yang , Tao Zhang , Chunling Liu , Kam Chuen Yuen , Aiyi Liu

Biomechanics and human movement research often involves measuring multiple kinematic or kinetic variables regularly throughout a movement, yielding data that present as smooth, multivariate, time-varying curves and are naturally amenable to…

This article presents a reformulation of the Theory of Functional Connections: a general methodology for functional interpolation that can embed a set of user-specified linear constraints. The reformulation presented in this paper exploits…

Numerical Analysis · Mathematics 2020-08-07 Carl Leake , Hunter Johnston , Daniele Mortari

The input data features set for many data driven tasks is high-dimensional while the intrinsic dimension of the data is low. Data analysis methods aim to uncover the underlying low dimensional structure imposed by the low dimensional hidden…

Machine Learning · Computer Science 2019-01-30 Moshe Salhov , Ofir Lindenbaum , Yariv Aizenbud , Avi Silberschatz , Yoel Shkolnisky , Amir Averbuch

This article focuses on covariance estimation for multi-view data. Popular approaches rely on factor-analytic decompositions that have shared and view-specific latent factors. Posterior computation is conducted via expensive and brittle…

Methodology · Statistics 2026-04-20 Lorenzo Mauri , David B. Dunson

We introduce Adaptive Functional Principal Component Analysis, a novel method to capture directions of variation in functional data that exhibit sharp changes in smoothness. We first propose a new adaptive scatterplot smoothing technique…

Methodology · Statistics 2023-10-04 Angel Garcia de la Garza , Britton Sauerbrei , Adam Hantman , Jeff Goldsmith

A new nonparametric graphical test of significance of a covariate in functional GLM is proposed. Our approach is especially interesting due to its functional graphical interpretation of the results. As such it is able to find not only if…

Methodology · Statistics 2019-02-14 Tomas Mrkvicka , Tomas Roskovec , Michael Rost

Estimating the joint probability mass function (PMF) of a set of random variables lies at the heart of statistical learning and signal processing. Without structural assumptions, such as modeling the variables as a Markov chain, tree, or…

Signal Processing · Electrical Eng. & Systems 2018-10-17 Nikos Kargas , Nicholas D. Sidiropoulos , Xiao Fu

In this study, we propose a function-on-function linear quantile regression model that allows for more than one functional predictor to establish a more flexible and robust approach. The proposed model is first transformed into a…

Methodology · Statistics 2021-11-11 Ufuk Beyaztas , Han Lin Shang

As high-dimensional and high-frequency data are being collected on a large scale, the development of new statistical models is being pushed forward. Functional data analysis provides the required statistical methods to deal with large-scale…

Statistics Theory · Mathematics 2020-07-08 Israel Martínez-Hernández , Marc G. Genton

Estimation of mean and covariance functions is fundamental for functional data analysis. While this topic has been studied extensively in the literature, a key assumption is that there are enough data in the domain of interest to estimate…

Methodology · Statistics 2020-09-01 Zhenhua Lin , Jane-Ling Wang , Qixian Zhong