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Prediction-powered inference (PPI) enables valid statistical inference by combining experimental data with machine learning predictions. When a sufficient number of high-quality predictions is available, PPI results in more accurate…

Machine Learning · Statistics 2025-08-18 Stefano Cortinovis , François Caron

Meta-analysis can be formulated as combining $p$-values across studies into a joint $p$-value function, from which point estimates and confidence intervals can be derived. We extend the meta-analytic estimation framework based on combined…

Methodology · Statistics 2025-10-21 David Kronthaler , Leonhard Held

After some general remarks about the interrelation between philosophical and statistical thinking, the discussion centres largely on significance tests. These are defined as the calculation of $p$-values rather than as formal procedures for…

Statistics Theory · Mathematics 2007-06-13 Deborah G. Mayo , D. R. Cox

We marshall the arguments for preferring Bayesian hypothesis testing and confidence sets to frequentist ones. We define admissible solutions to inference problems, noting that Bayesian solutions are admissible. We give seven weaker…

Statistics Theory · Mathematics 2024-05-22 Roger Sewell

We develop, discuss, and compare several inference techniques to constrain theory parameters in collider experiments. By harnessing the latent-space structure of particle physics processes, we extract extra information from the simulator.…

High Energy Physics - Phenomenology · Physics 2018-09-19 Johann Brehmer , Kyle Cranmer , Gilles Louppe , Juan Pavez

Practical employment of Bayesian trial designs is still rare. Even if accepted in principle, the regulators have commonly required that such designs be calibrated according to an upper bound for the frequentist type I error rate. This…

Methodology · Statistics 2026-03-25 Elja Arjas , Dario Gasbarra

Uncertainty quantification for complex deep learning models is increasingly important as these techniques see growing use in high-stakes, real-world settings. Currently, the quality of a model's uncertainty is evaluated using…

Machine Learning · Computer Science 2021-12-15 Benjamin Kompa , Jasper Snoek , Andrew Beam

Upper limits and confidence intervals are a convenient way to present experimental results. With modern experiments producing more and more data, it is often necessary to reduce the volume of the results for convenient distribution. A…

General Relativity and Quantum Cosmology · Physics 2024-10-02 Vladimir Dergachev

Likelihood profiling is an efficient and powerful frequentist approach for parameter estimation, uncertainty quantification and practical identifiablity analysis. Unfortunately, these methods cannot be easily applied for stochastic models…

Model selection strategies have been routinely employed to determine a model for data analysis in statistics, and further study and inference then often proceed as though the selected model were the true model that were known a priori. This…

Methodology · Statistics 2018-02-13 Priyam Mitra , Heng Lian , Ritwik Mitra , Hua Liang , Min-ge Xie

Frequentist coverage of $(1-\alpha)$-highest posterior density (HPD) credible sets is studied in a signal plus noise model under a large class of noise distributions. We consider a specific class of spike-and-slab prior distributions.…

Statistics Theory · Mathematics 2020-03-11 Kevin Duisters , Johannes Schmidt-Hieber

In an empirical Bayes analysis, we use data from repeated sampling to imitate inferences made by an oracle Bayesian with extensive knowledge of the data-generating distribution. Existing results provide a comprehensive characterization of…

Methodology · Statistics 2021-09-09 Nikolaos Ignatiadis , Stefan Wager

The primary objective of this paper is to revisit and make a case for the merits of R.A. Fisher's objections to the decision-theoretic framing of frequentist inference. It is argued that this framing is congruent with the Bayesian but…

Methodology · Statistics 2016-08-02 Aris Spanos

As machine learning-based prediction systems are increasingly used in high-stakes situations, it is important to understand how such predictive models will perform upon deployment. Distribution-free uncertainty quantification techniques…

Machine Learning · Computer Science 2025-06-12 Jake C. Snell , Thomas L. Griffiths

In the analysis of survey data it is of interest to estimate and quantify uncertainty about means or totals for each of several non-overlapping subpopulations, or areas. When the sample size for a given area is small, standard confidence…

Methodology · Statistics 2018-09-26 Kyle Burris , Peter Hoff

We propose modified frequentist definitions for the determination of confidence intervals for the case of Poisson statistics. We require that 1-\beta^{'} \geq \sum_{n=o}^{n_{obs}+k} P(n|\lambda) \geq \alpha^{'}. We show that this definition…

Data Analysis, Statistics and Probability · Physics 2015-06-11 S. I. Bitioukov , N. V. Krasnikov

Central limit theorems (CLTs) have a long history in probability and statistics. They play a fundamental role in constructing valid statistical inference procedures. Over the last century, various techniques have been developed in…

Statistics Theory · Mathematics 2023-06-27 Arisina Banerjee , Arun K Kuchibhotla

We consider the problem of inferring constraints on a high-dimensional parameter space with a computationally expensive likelihood function. We propose a machine learning algorithm that maps out the Frequentist confidence limit on parameter…

Cosmology and Nongalactic Astrophysics · Physics 2014-09-25 Scott F. Daniel , Andrew J. Connolly , Jeff Schneider

We propose a method for setting limits that avoids excluding parameter values for which the sensitivity falls below a specified threshold. These "power-constrained" limits (PCL) address the issue that motivated the widely used CLs…

Data Analysis, Statistics and Probability · Physics 2011-05-17 Glen Cowan , Kyle Cranmer , Eilam Gross , Ofer Vitells

Profile likelihood confidence intervals are a robust alternative to Wald's method if the asymptotic properties of the maximum likelihood estimator are not met. However, the constrained optimization problem defining profile likelihood…

Computation · Statistics 2021-05-10 Samuel M. Fischer , Mark A. Lewis
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