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An important prerequisite for the analysis of spike synchrony in extracellular recordings is the extraction of single unit activity from the recorded multi unit signal. To identify single units (SUs), potential spikes are detected and…

Neurons and Cognition · Quantitative Biology 2018-11-01 Jeyathevy Sukiban , Nicole Voges , Till A. Dembek , Robin Pauli , Michael Denker , Immo Weber , Lars Timmermann , Sonja Grün

Estimating neuron location from extracellular recordings is essential for developing advanced brain-machine interfaces. Accurate neuron localization improves spike sorting, which involves detecting action potentials and assigning them to…

Neurons and Cognition · Quantitative Biology 2025-08-20 Hao Zhao , Xinhe Zhang , Arnau Marin-Llobet , Xinyi Lin , Jia Liu

Spike sorting is an essential process in neural recording, which identifies and separates electrical signals from individual neurons recorded by electrodes in the brain, enabling researchers to study how specific neurons communicate and…

Neurons and Cognition · Quantitative Biology 2025-12-23 Yimu Zhang , Dongqi Han , Yansen Wang , Zhenning Lv , Yu Gu , Dongsheng Li

Model selection is a major challenge in non-parametric clustering. There is no universally admitted way to evaluate clustering results for the obvious reason that no ground truth is available. The difficulty to find a universal evaluation…

Machine Learning · Computer Science 2023-05-18 Alex Mourer , Florent Forest , Mustapha Lebbah , Hanane Azzag , Jérôme Lacaille

Reliable spike detection and sorting, the process of assigning each detected spike to its originating neuron, is an essential step in the analysis of extracellular electrical recordings from neurons. The volume and complexity of the data…

Neurons and Cognition · Quantitative Biology 2018-09-05 Matthias H. Hennig , Cole Hurwitz , Martino Sorbaro

How can we assess the reliability of a dataset without access to ground truth? We introduce the problem of reliability scoring for datasets collected from potentially strategic sources. The true data are unobserved, but we see outcomes of…

Machine Learning · Computer Science 2025-10-21 Yiling Chen , Shi Feng , Paul Kattuman , Fang-Yi Yu

Spike sorting algorithms are used to separate extracellular recordings of neuronal populations into single-unit spike activities. The development of customized hardware implementing spike sorting algorithms is burgeoning. However, there is…

Machine Learning · Computer Science 2025-01-30 Tim Zhang , Corey Lammie , Mostafa Rahimi Azghadi , Amirali Amirsoleimani , Majid Ahmadi , Roman Genov

Spike sorting is a fundamental preprocessing step for many neuroscience studies which rely on the analysis of spike trains. In this paper, we present two unsupervised spike sorting algorithms based on discriminative subspace learning. The…

Computer Vision and Pattern Recognition · Computer Science 2014-08-25 Mohammad Reza Keshtkaran , Zhi Yang

One step in the conventional analysis of extracellularly recorded neuronal data is spike sorting, which separates electrical signal into action potentials from different neurons. Because spike sorting involves human judgment, it can be…

Neurons and Cognition · Quantitative Biology 2007-05-23 Artur Luczak , Nandakumar S. Narayanan

We provide methods to validate and compare sensor outputs, or inference algorithms applied to sensor data, by adapting statistical scoring rules. The reported output should either be in the form of a prediction interval or of a parameter…

Data Analysis, Statistics and Probability · Physics 2015-07-07 A. D. Martin , T. C. A. Molteno , M. Parry

State space subspace algorithms for input-output systems have been widely applied but also have a reasonably well-developedasymptotic theory dealing with consistency. However, guaranteeing the stability of the estimated system matrix is a…

Systems and Control · Electrical Eng. & Systems 2024-08-19 Xinhui Rong , Victor Solo

In the last decade, there have been major advances in clusterless decoding algorithms for neural data analysis. These algorithms use the theory of marked point processes to describe the joint activity of many neurons simultaneously, without…

Neurons and Cognition · Quantitative Biology 2025-12-09 Azar Ghahari , Uri T. Eden

This paper aims to test the number of spikes in a generalized spiked covariance matrix, the spiked eigenvalues of which may be extremely larger or smaller than the non-spiked ones. For a high-dimensional problem, we first propose a general…

Methodology · Statistics 2022-03-15 Dandan Jiang

We describe a seriation algorithm for ranking a set of items given pairwise comparisons between these items. Intuitively, the algorithm assigns similar rankings to items that compare similarly with all others. It does so by constructing a…

Machine Learning · Computer Science 2016-03-11 Fajwel Fogel , Alexandre d'Aspremont , Milan Vojnovic

This paper proposes a set of criteria to evaluate the objectiveness of explanation methods of neural networks, which is crucial for the development of explainable AI, but it also presents significant challenges. The core challenge is that…

Machine Learning · Computer Science 2019-11-21 Hao Zhang , Jiayi Chen , Haotian Xue , Quanshi Zhang

A vast number of different methods are available for unsupervised classification. Since no algorithm and parameter setting performs best in all types of data, there is a need for cluster validation to select the actually best-performing…

Machine Learning · Computer Science 2023-08-09 Zoltán Botta-Dukát

The advent of large-scale and high-density extracellular recording devices allows simultaneous recording from thousands of neurons. However, the complexity and size of the data makes it mandatory to develop robust algorithms for fully…

Neurons and Cognition · Quantitative Biology 2019-12-03 Gerrit Hilgen

Spike-sorting techniques attempt to classify a series of noisy electrical waveforms according to the identity of the neurons that generated them. Existing techniques perform this classification ignoring several properties of actual neurons…

Quantitative Methods · Quantitative Biology 2007-05-23 Christophe Pouzat

Methods to certify the robustness of neural networks in the presence of input uncertainty are vital in safety-critical settings. Most certification methods in the literature are designed for adversarial or worst-case inputs, but researchers…

Machine Learning · Computer Science 2023-01-26 Brendon G. Anderson , Somayeh Sojoudi

Model selection on validation data is an essential step in machine learning. While the mixing of data between training and validation is considered taboo, practitioners often violate it to increase performance. Here, we offer a simple,…

Machine Learning · Statistics 2018-02-19 Guy Tennenholtz , Tom Zahavy , Shie Mannor
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