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We investigate the critical dissipation of the double-well quantum mechanics. We adopt two-state approximation to define effective Ising models and apply the block decimation renormalization group and the finite range scaling method…

Statistical Mechanics · Physics 2015-06-11 Ken-Ichi Aoki , Tamao Kobayashi

We study an approximation scheme based on a second quantization method for a chemical master equation. Small systems, such as cells, could not be studied by the traditional rate equation approach because fluctuation effects are very large…

Chemical Physics · Physics 2010-06-18 Jun Ohkubo

We investigate large deviations of the work performed in a quantum quench across two different phases separated by a quantum critical point, using as example the Dicke model quenched from its superradiant to its normal phase. We extract the…

Statistical Mechanics · Physics 2020-02-10 P. Rotondo , J. Minar , J. P. Garrahan , I. Lesanovsky , M. Marcuzzi

We study a micro and macroscopic model for chemical reactions with feedback between reactions and temperature of the solute. The first result concerns the quasipotential as the large-deviation rate of the microscopic invariant measure. The…

Mathematical Physics · Physics 2021-11-25 D. R. Michiel Renger

We consider the context of molecular motors modelled by a diffusion process driven by the gradient of a weakly periodic potential that depends on an internal degree of freedom. The switch of the internal state, that can freely be…

Probability · Mathematics 2024-02-02 Serena Della Corte , Richard C. Kraaij

Most biochemical reactions in living cells are open systems interacting with environment through chemostats to exchange both energy and materials. At a mesoscopic scale, the number of each species in those biochemical reactions can be…

Optimization and Control · Mathematics 2022-11-08 Yuan Gao , Jian-Guo Liu

To model bio-chemical reaction systems with diffusion one can either use stochastic, microscopic reaction-diffusion master equations or deterministic, macroscopic reaction-diffusion system. The connection between these two models is not…

Analysis of PDEs · Mathematics 2023-06-21 Malcolm Egan , Bao Quoc Tang

We consider reaction networks that admit a singular perturbation reduction in a certain parameter range. The focus of this paper is on deriving "small parameters" (briefly for small perturbation parameters), to gauge the accuracy of the…

Dynamical Systems · Mathematics 2023-03-21 Justin Eilertsen , Santiago Schnell , Sebastian Walcher

In many stochastic models, the observables of interest are naturally encoded in double transforms (e.g., Laplace transforms) that couple spatial and temporal variables. Notably, the double transform often provides the only analytically…

Probability · Mathematics 2026-05-21 Giampaolo Cristadoro , Gaia Pozzoli

We present a fully adaptive multiresolution scheme for spatially two-dimensional, possibly degenerate reaction-diffusion systems, focusing on combustion models and models of pattern formation and chemotaxis in mathematical biology.…

Numerical Analysis · Mathematics 2008-07-10 Mostafa Bendahmane , Raimund Bürger , Ricardo Ruiz Baier , Kai Schneider

Due to the intrinsic complexity and nonlinearity of chemical reactions, direct applications of traditional machine learning algorithms may face with many difficulties. In this study, through two concrete examples with biological background,…

Molecular Networks · Quantitative Biology 2020-06-02 Wuyue Yang , Liangrong Peng , Yi Zhu , Liu Hong

Molecule- and particle-based simulations provide the tools to test, in microscopic detail, the validity of classical nucleation theory. In this endeavour, determining nucleation mechanisms and rates for phase separation requires an…

Materials Science · Physics 2023-02-27 Aaron R. Finney , Matteo Salvalaglio

We prove a large-deviation principle (LDP) for the sample paths of jump Markov processes in the small noise limit when, possibly, all the jump rates vanish uniformly, but slowly enough, in a region of the state space. We further discuss the…

Probability · Mathematics 2021-02-26 Andrea Agazzi , Luisa Andreis , Robert I. A. Patterson , D. R. Michiel Renger

We develop an efficient method to calculate probabilities of large deviations from the typical behavior (rare events) in reaction--diffusion systems. The method is based on a semiclassical treatment of underlying "quantum" Hamiltonian,…

Statistical Mechanics · Physics 2009-11-10 Vlad Elgart , Alex Kamenev

We study the large-time behavior of (weak) solutions to a two-scale reaction-diffusion system coupled with a nonlinear ordinary differential equations modeling the partly dissipative corrosion of concrete (/cement)-based materials with…

Analysis of PDEs · Mathematics 2013-05-22 Toyohiko Aiki , Adrian Muntean

Reaction-diffusion systems, which consist of the reacting particles subject to diffusion process, constitute one of the common examples of non-linear statistical systems. In low space dimensions $d \leq 2$ the usual description by means of…

Statistical Mechanics · Physics 2023-10-24 Michal Hnatič , Matej Kecer , Tomáš Lučivjanský

We consider high temperature KMS states for quantum spin systems on a lattice. We prove a large deviation principle for the distribution of empirical averages $\frac{1}{|\Lambda|} \sum_{i\in\Lambda} X_i$, where the $X_i$'s are copies of a…

Mathematical Physics · Physics 2009-11-10 K. Netocny , F. Redig

The development of mechanistic models of biological systems is a central part of Systems Biology. One major task in developing these models is the inference of the correct model parameters. Due to the size of most realistic models and their…

Quantitative Methods · Quantitative Biology 2016-06-28 Jan Mikelson , Mustafa Khammash

Chemical reactions can be modeled by a random time-changed Poisson process on countable states. The macroscopic behaviors, such as large fluctuations, can be studied via the WKB reformulation. The WKB reformulation for the backward equation…

Analysis of PDEs · Mathematics 2023-06-07 Yuan Gao , Jian-Guo Liu

We study a stochastic two-species chemical reaction system with two mechanisms. One mechanism consists of chemical interactions which govern the overall drift of species amounts in the system; the other mechanism consists of resampling,…

Probability · Mathematics 2014-05-06 John K. McSweeney , Lea Popovic