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The last two decades have seen intense scientific and regulatory interest in the health effects of particulate matter (PM). Influential epidemiological studies that characterize chronic exposure of individuals rely on monitoring data that…

Applications · Statistics 2009-06-09 Christopher J. Paciorek , Jeff D. Yanosky , Robin C. Puett , Francine Laden , Helen H. Suh

We study extended infection fronts advancing over a spatially uniform susceptible population by solving numerically a diffusive Kermack McKendrick SIR model with a dichotomous spatially random transmission rate, in two dimensions. We find a…

Disordered Systems and Neural Networks · Physics 2019-06-11 A. B. Kolton , K. Laneri

Models for resident infectious diseases, like the SIRS model, may settle into an endemic state with constant numbers of susceptible ($S$), infected ($I$) and recovered ($R$) individuals, where recovered individuals attain a temporary…

Populations and Evolution · Quantitative Biology 2024-11-05 Daniel Henrik Nevermann , Claudius Gros

Epidemics are inherently stochastic, and stochastic models provide an appropriate way to describe and analyse such phenomena. Given temporal incidence data consisting of, for example, the number of new infections or removals in a given time…

Methodology · Statistics 2024-05-24 Sam A. Whitaker , Andrew Golightly , Colin S. Gillespie , Theodore Kypraios

The integration of empirical data in computational frameworks to model the spread of infectious diseases poses challenges that are becoming pressing with the increasing availability of high-resolution information on human mobility and…

Populations and Evolution · Quantitative Biology 2013-04-24 Anna Machens , Francesco Gesualdo , Caterina Rizzo , Alberto E Tozzi , Alain Barrat , Ciro Cattuto

In contrast to the common assumption in epidemic models that the rate of infection between individuals is constant, in reality, an individual's viral load determines their infectiousness. We compare the average and individual reproductive…

Populations and Evolution · Quantitative Biology 2021-12-07 Nicholas Landry

Routine public health surveillance of notifiable infectious diseases gives rise to weekly counts of reported cases -- possibly stratified by region and/or age group. We investigate how an age-structured social contact matrix can be…

Methodology · Statistics 2017-05-12 Sebastian Meyer , Leonhard Held

The Covid-19 pandemic has taken millions of lives, demonstrating the tragedy and disruption of respiratory diseases, and how difficult they can be to manage. However, there is still significant debate in the scientific community as to which…

Dynamical Systems · Mathematics 2021-09-03 Panagiotis Demis , Ishanki De Mel , Hayley Wragg , Michael Short , Oleksiy V. Klymenko

In this paper we first introduce the general stochastic epidemic model for the spread of infectious diseases. Then we give methods for inferring model parameters such as the basic reproduction number $R_0$ and vaccination coverage $v_c$…

Methodology · Statistics 2014-11-14 Tom Britton , Federica Giardina

The widely used susceptible-infected-recovered (S-I-R) epidemic model assumes a uniform, well-mixed population, and incorporation of spatial heterogeneities remains a major challenge. Understanding failures of the mixing assumption is…

Soft Condensed Matter · Physics 2024-04-23 P. Forgacs , A. Libal , C. Reichhardt , N. Hengartner , C. J. O. Reichhardt

We study the qualitative properties of a spatial diffusive heterogeneous SIR model, that appears in mathematical epidemiology to describe the spread of an infectious disease in a population. The model we consider consists in a system of…

Analysis of PDEs · Mathematics 2020-05-15 Romain Ducasse

This chapter surveys univariate and multivariate methods for infectious disease outbreak detection. The setting considered is a prospective one: data arrives sequentially as part of the surveillance systems maintained by public health…

Methodology · Statistics 2017-11-27 Benjamin Allévius , Michael Höhle

We analyze infection spreading processes in a system where only a fraction $p$ of individuals can be affected by disease, while remaining $1-p$ individuals are immune. Such a picture can emerge as a natural consequence of previously…

Disordered Systems and Neural Networks · Physics 2021-12-06 V. Blavatska , Yu. Holovatch

A class of multiple-timescale asymptotic solutions to the equations of the susceptible-infected-recovered (SIR) model is presented for the case of high basic reproduction number, with the inverse of the latter employed as the expansion…

Populations and Evolution · Quantitative Biology 2025-12-25 Oleg B. Shiryaev

We consider a multi-species reaction-diffusion system that arises in epidemiology to describe the spread of several strains, or variants, of a disease in a population. Our model is a natural spatial, multi-species, extension of the…

Analysis of PDEs · Mathematics 2022-08-02 Romain Ducasse , Samuel Nordmann

A class of stochastic vector-borne infectious disease models is derived and studied. The class type is determined by a general nonlinear incidence rate of the disease. The disease spreads in a highly random environment with variability from…

Populations and Evolution · Quantitative Biology 2020-05-05 Divine Wanduku

Together with the universally recognized SIR model, several approaches have been employed to understand the contagious dynamics of interacting particles. Here, Active Brownian particles (ABP) are introduced to model the contagion dynamics…

Soft Condensed Matter · Physics 2021-08-03 Ariel Norambuena , Felipe Valencia , Francisca Guzmán-Lastra

A spatial point process can be characterized by an intensity function which predicts the number of events that occur across space. In this paper, we develop a method to infer predictive intensity intervals by learning a spatial model using…

Machine Learning · Statistics 2020-07-06 Muhammad Osama , Dave Zachariah , Petre Stoica

The annual occurrence of many infectious diseases remains a constant burden to public health systems. The seasonal patterns in respiratory disease incidence observed in temperate regions have been attributed to the impact of environmental…

Populations and Evolution · Quantitative Biology 2013-11-13 Marguerite Robinson , Yannis Drossinos , Nikolaos I. Stilianakis

A numerical framework for the 'real-time' estimation of the infection risk from airborne diseases (e.g., SARS-CoV-2) in indoor spaces such as hospitals, restaurants, cinemas or teaching rooms is proposed. The developed model is based on the…