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Short-time human travel behaviour can be described by a power law with respect to distance. We incorporate this information in space-time models for infectious disease surveillance data to better capture the dynamics of disease spread. Two…
We introduce a new type of point process model to describe the incidence of contagious diseases. The model is a variant of the Hawkes self-exciting process and exhibits similar clustering but without the restriction that the component…
Spatio-temporal interaction is inherent to cases of infectious diseases and occurrences of earthquakes, whereas the spread of other events, such as cancer or crime, is less evident. Statistical significance tests of space-time clustering…
We introduce a kinetic framework for modeling the time evolution of the statistical distributions of the population densities in the three compartments of susceptible, infectious, and recovered individuals, under epidemic spreading driven…
Here, we introduce a novel framework for modelling the spatiotemporal dynamics of disease spread known as conditional logistic individual-level models (CL-ILM's). This framework alleviates much of the computational burden associated with…
In this manuscript, we develop a mobility-based Susceptible-Infectious-Recovered (SIR) model to elucidate the dynamics of pandemic propagation. While traditional SIR models within the field of epidemiology aptly characterize transitions…
Spatio-temporal extensions of familiar compartment models for disease transmission incorporating diffusive behavior, or interactions between individuals at separate locations, are explored. The models considered have the character of…
The pattern formation and spatial spread of infectious populations are investigated using a kernel-based Susceptible-Infectious-Recovered (SIR) model applicable across a wide range of basic reproduction numbers $R_o$. The focus is on the…
Multiplex immunofluorescence (mIF) imaging technology facilitates the study of the tumour microenvironment in cancer patients. Due to the capabilities of this emerging bioimaging technique, it is possible to statistically analyse, for…
Reliable estimation of spatio-temporal trends in population-level HIV incidence is becoming an increasingly critical component of HIV prevention policy-making. However, direct measurement is nearly impossible. Current, widely used models…
We develop a multiple compartment Susceptible-Infected-Recovered (SIR) model to analyze the spread of several infectious diseases through different geographic areas. Additionally, we propose a data-quality sensitive optimization framework…
Infectious disease models can be of great use for understanding the underlying mechanisms that influence the spread of diseases and predicting future disease progression. Modeling has been increasingly used to evaluate the potential impact…
The SIR model is a classical model characterizing the spreading of infectious diseases. This model describes the time-dependent quantity changes among Susceptible, Infectious, and Recovered groups. By introducing space-depend effects such…
In this study, we present an integro-differential model to simulate the local spread of infections. The model incorporates a standard susceptible-infected-recovered (\textit{SIR}-) model enhanced by an integral kernel, allowing for…
Contemporary epidemiological models often involve spatial variation, providing an avenue to investigate the averaged dynamics of individual movements. In this work, we extend a recent model by Vaziry, Kolokolnikov, and Kevrekidis [Royal…
How is the progression of a virus influenced by properties intrinsic to individual cells? We address this question by studying the susceptibility of cells infected with two strains of the human respiratory syncytial virus (RSV-A and RSV-B)…
We introduce a modified SIR model with memory for the dynamics of epidemic spreading in a constant population of individuals. Each individual is in one of the states susceptible (${\bf S}$), infected (${\bf I}$) or recovered (${\bf R}$). In…
Modelling epidemics is crucial for understanding the emergence, transmission, impact and control of diseases. Spatial individual-level models (ILMs) that account for population heterogeneity are a useful tool, accounting for factors such as…
A compartmental deterministic model that allows (1) immunity from two stages of infection and carriage, and (2) disease induced death, is used in studying the dynamics of meningitis epidemic process in a closed population. It allows for…
Human mobility is a key factor in spatial disease dynamics and related phenomena. In computational models host mobility is typically modelled by diffusion in space or on metapolulation networks. Alternatively, an effective force of…