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We investigate knotting probabilities of long double-stranded DNA strands in a coarse-grained Kratky-Porod model for DNA with Monte Carlo simulations. Various ionic conditions are implemented by adjusting the effective diameter of monomers.…

Soft Condensed Matter · Physics 2022-12-26 Sarah Wettermann , Ranajay Datta , Peter Virnau

The experiment that the high spin selectivity and the length-dependent spin polarization are observed in double-stranded DNA [Science ${\bf 331}$, 894 (2011)], is elucidated by considering the combination of the spin-orbit coupling, the…

Mesoscale and Nanoscale Physics · Physics 2015-06-03 Ai-Min Guo , Qing-feng Sun

A mechanism of double strand breaking (DSB) in DNA due to the action of two electrons is considered. These are the electrons produced in the vicinity of DNA molecules due to ionization of water molecules with a consecutive emission of two…

Biological Physics · Physics 2015-06-03 Eugene Surdutovich , Andrey V. Solov'yov

The percentage and sequence of AT and GC base pairs and charges on the DNA backbone contribute significantly to the stiffness of DNA. This elastic property of DNA also changes with small interacting ligands. The single-molecule force…

Soft Condensed Matter · Physics 2017-02-02 Anurag Singh , Amar Nath Gupta

The free energy of looping DNA by proteins and protein complexes determines to what extent distal DNA sites can affect each other. We inferred its in vivo value through a combined computational-experimental approach for different lengths of…

Biomolecules · Quantitative Biology 2007-05-23 Leonor Saiz , J. Miguel Rubi , Jose M. G. Vilar

We study the trapping of charged particles and macromolecules (such as DNA) in salt gradients in aqueous solutions. The source for the salt gradient can be as simple as a dissolving ionic crystal, as shown by McDermott et al. [Langmuir 28,…

Soft Condensed Matter · Physics 2025-12-09 Richard P. Sear , Patrick B. Warren

The conformational vibrations of Z-DNA with counterions are studied in framework of phenomenological model developed. The structure of left-handed double helix with counterions neutralizing the negatively charged phosphate groups of DNA is…

Biomolecules · Quantitative Biology 2013-05-01 S. M. Perepelytsya , S. N. Volkov

Persistence length of dsDNA is known to decrease with increase in ionic concentration of the solution. In contrast to this, here we show that persistence length of dsDNA increases dramatically as a function of ionic liquid (IL)…

Biological Physics · Physics 2018-08-15 Ashok Garai , Debostuti Ghoshdastidar , Sanjib Senapati , Prabal K. Maiti

DNA stretching experiments are usually interpreted using the worm-like chain model; the persistence length A appearing in the model is then interpreted as the elastic stiffness of the double helix. In fact the persistence length obtained by…

Soft Condensed Matter · Physics 2009-10-30 Philip Nelson

Although mechanical properties of DNA are well characterized at the kilo base-pair range, a number of recent experiments have suggested that DNA is more flexible at shorter length scales, which correspond to the regime that is crucial for…

Biomolecules · Quantitative Biology 2015-06-11 Agnes Noy , Ramin Golestanian

We here examine the nonlinear dynamics of artificial homogeneous DNA chain relying on the plain-base rotator model. It is shown that such dynamics can exhibit kink and antikink solitons of sine-Gordon type. In that respect we propose…

Biological Physics · Physics 2015-06-05 S. Zdravković , M. V. Satarić , M. Daniel

The morphology of DNA is strongly influenced by its surrounding environment, including factors such as pH, salt type and valency, and the presence of polymers. Inorganic salts are known to reduce the DNA chain length through mechanisms like…

Soft Condensed Matter · Physics 2026-03-03 Anuj Chhabra , Sandip Mandal , Yugang Zhang , Oleg Gang , Prabal K. Maiti , Sunita Srivastava

To study the elastic properties of rod-like DNA nanostructures, we perform long simulations of these structure using the oxDNA coarse-grained model. By analysing the fluctuations in these trajectories we obtain estimates of the bend and…

The intrinsic double helix conformation of the DNA strands is known to be the key ingredient of control of the electric current through the DNA by the perpendicular (gate) electric field. We show theoretically that Bloch oscillations in the…

Materials Science · Physics 2009-10-25 A. V. Malyshev , V. A. Malyshev , F. Dominguez-Adame

Solid-state nanopore DNA sequencers present mechanical and chemical stability, reusability, and large-scale integrability. However, their development is hindered by the absence of a protein-free mechanism for controlling DNA translocation,…

Biological Physics · Physics 2026-03-17 Tomoki Ohkubo

In this paper we consider a physical system in which two DNA molecules braid about each other. The distance between the two molecular ends, on either side of the braid, is held at a distance much larger than supercoiling radius of the…

Soft Condensed Matter · Physics 2014-07-02 Dominic J. , Lee

Even though the persistence length $L_P$ of double-stranded DNA plays a pivotal role in cell biology and nanotechnologies, its dependence on ionic strength $I$ lacks a consensual description. Using a high-throughput single-molecule…

The mechanism of threshold elongation (overstretching) of DNA macromolecules under the action of external force is studied within the framework of phenomenological approach. When considering the task it is taken into account that…

Biomolecules · Quantitative Biology 2016-02-22 Sergey N. Volkov

The combination of self-assembly and electronic properties as well as its true nanoscale dimensions make DNA a promising candidate for a building block of single molecule electronics. We argue that the intrinsic double helix conformation of…

Materials Science · Physics 2007-05-23 A. V. Malyshev

The distance-resolved effective interaction potential between two parallel DNA molecules is calculated by computer simulations with explicit tetravalent counterions and monovalent salt. Adding counterions first yields an attractive minimum…

Soft Condensed Matter · Physics 2009-11-10 E. Allahyarov , H. Löwen , G. Gompper