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We review a selection of methods for performing enhanced sampling in molecular dynamics simulations. We consider methods based on collective variable biasing and on tempering, and offer both historical and contemporary perspectives. In…

Statistical Mechanics · Physics 2014-01-03 Cameron Abrams , Giovanni Bussi

We study metastability and mixing time for a non-reversible probabilistic cellular automaton. With a suitable choice of the parameters, we first show that the stationary distribution is close in total variation to a low temperature Ising…

Probability · Mathematics 2014-07-25 Paolo Dai Pra , Benedetto Scoppola , Elisabetta Scoppola

We investigate the class of tempered stable distributions and their associated processes. Our analysis of tempered stable distributions includes limit distributions, parameter estimation and the study of their densities. Regarding tempered…

Probability · Mathematics 2025-11-21 Uwe Küchler , Stefan Tappe

We discuss the possibility of implementing asynchronous replica-exchange (or parallel tempering) molecular dynamics. In our scheme, the exchange attempts are driven by asynchronous messages sent by one of the computing nodes, so that…

Computational Physics · Physics 2009-11-23 Giovanni Bussi

From the underlying Master equations we derive one-dimensional stochastic processes that describe generalized ensemble simulations as well as tempering (simulated and parallel) simulations. The representations obtained are either in the…

Statistical Mechanics · Physics 2008-11-26 Walter Nadler , Ulrich H. E. Hansmann

We introduce a notion of geometric tempering using exponentially-dampened Mittag-Leffler tempering functions and closely investigate the univariate case. Characteristic exponents and cumulants are calculated, as well as spectral densities.…

Probability · Mathematics 2023-05-26 Lorenzo Torricelli

In this paper we propose a general framework of performing MCMC with only a mini-batch of data. We show by estimating the Metropolis-Hasting ratio with only a mini-batch of data, one is essentially sampling from the true posterior raised to…

Computation · Statistics 2018-05-23 Dangna Li , Wing H Wong

Extreme weather events epitomize high cost: to society through their physical impacts, and to computer servers that simulate them to assess risk and advance physical understanding. It costs hundreds of simulation years to sample a few…

Atmospheric and Oceanic Physics · Physics 2026-04-14 Justin Finkel , Paul A. O'Gorman

Monte Carlo simulations of the Ising model play an important role in the field of computational statistical physics, and they have revealed many properties of the model over the past few decades. However, the effect of frustration due to…

Disordered Systems and Neural Networks · Physics 2017-01-04 Ye Fang , Sheng Feng , Ka-Ming Tam , Zhifeng Yun , Juana Moreno , J. Ramanujam , Mark Jarrell

We perform large scale simulations to characterize the transition in quenched QCD. It is shown by a rigorous finite size scaling that the transition is of first order. After this qualitative feature quantitative results are obtained with…

High Energy Physics - Lattice · Physics 2022-04-19 S. Borsanyi , Z. Fodor , D. A. Godzieba , R. Kara , P. Parotto , D. Sexty

The problem of simulating the thermal behavior of quantum systems remains a central open challenge in quantum computing. Unlike well-established quantum algorithms for unitary dynamics, \emph{provably efficient} algorithms for preparing…

Quantum Physics · Physics 2026-05-14 Dominik Hahn , Ryan Sweke , Abhinav Deshpande , Oles Shtanko

We study the efficiency of parallel tempering Monte Carlo technique for calculating true ground states of the Edwards-Anderson spin glass model. Bimodal and Gaussian bond distributions were considered in two and three-dimensional lattices.…

Statistical Mechanics · Physics 2015-05-13 F. Roma , S. Risau-Gusman , A. J. Ramirez-Pastor , F. Nieto , E. E. Vogel

Finite element models without simplifying assumptions can accurately describe the spatial and temporal distribution of heat in machine tools as well as the resulting deformation. In principle, this allows to correct for displacements of the…

Computational Engineering, Finance, and Science · Computer Science 2018-11-20 Andreas Naumann , Daniel Ruprecht , Joerg Wensch

The efficiency of Monte Carlo samplers is dictated not only by energetic effects, such as large barriers, but also by entropic effects that are due to the sheer volume that is sampled. The latter effects appear in the form of an entropic…

Computational Physics · Physics 2009-11-13 Cristian Predescu

The ferromagnetic Ising model on an $n\times n$ square lattice region $\Lambda$ with mixed boundary conditions can exhibit a phase transition as temperature varies. For this spin system, if we fix the spins on the top and bottom sides of…

Discrete Mathematics · Computer Science 2026-05-26 David Gillman , Dana Randall

A number of problems in a variety of fields are characterised by target distributions with a multimodal structure in which the presence of several isolated local maxima dramatically reduces the efficiency of Markov Chain Monte Carlo…

Methodology · Statistics 2009-07-31 Miquel Trias , Alberto Vecchio , John Veitch

Variational inference (VI) combined with data subsampling enables approximate posterior inference over large data sets, but suffers from poor local optima. We first formulate a deterministic annealing approach for the generic class of…

Machine Learning · Statistics 2016-05-31 Stephan Mandt , James McInerney , Farhan Abrol , Rajesh Ranganath , David Blei

We investigate the increase in efficiency of simulated and parallel tempering MCMC algorithms when using non-reversible updates to give them "momentum". By making a connection to a certain simple discrete Markov chain, we show that, under…

Statistics Theory · Mathematics 2025-01-29 Gareth O. Roberts , Jeffrey S. Rosenthal

Adaptive and interacting Markov chain Monte Carlo algorithms (MCMC) have been recently introduced in the literature. These novel simulation algorithms are designed to increase the simulation efficiency to sample complex distributions.…

Statistics Theory · Mathematics 2012-03-15 G. Fort , E. Moulines , P. Priouret

If accepted, the paper will be available at http://pubs.acs.org/journals/jpcbfh/

Chemical Physics · Physics 2007-05-23 Cristian Predescu , Mihaela Predescu , Cristian V. Ciobanu