English
Related papers

Related papers: Outcome Modeling Using Clinical DVH Data

200 papers

Purpose: To introduce novel dynamic structural parameters and evaluate their integration within a multimodal deep learning (DL) framework for predicting postoperative visual recovery in idiopathic full-thickness macular hole (iFTMH)…

Image and Video Processing · Electrical Eng. & Systems 2025-09-12 Yinzheng Zhao , Zhihao Zhao , Rundong Jiang , Louisa Sackewitz , Quanmin Liang , Mathias Maier , Daniel Zapp , Peter Charbel Issa , Mohammad Ali Nasseri

A basic principle in the design of observational studies is to approximate the randomized experiment that would have been conducted under controlled circumstances. Now, linear regression models are commonly used to analyze observational…

Methodology · Statistics 2022-07-08 Ambarish Chattopadhyay , Jose R. Zubizarreta

Inference in hierarchical nonlinear models needs careful consideration about targeting parameters that have either a conditional or population-average interpretation. For the special case of mixed-effects nonlinear sigmoidal models we…

Applications · Statistics 2017-07-11 Daniel Gerhard , Christian Ritz

Regression discontinuity (RD) is a widely used quasi-experimental design for causal inference. In the standard RD, the assignment to treatment is determined by a continuous pretreatment variable (i.e., running variable) falling above or…

Methodology · Statistics 2020-06-23 Fan Li , Andrea Mercatanti , Taneli Makinen , Andrea Silvestrini

Extracting activation patterns from functional Magnetic Resonance Images (fMRI) datasets remains challenging in rapid-event designs due to the inherent delay of blood oxygen level-dependent (BOLD) signal. The general linear model (GLM)…

Machine Learning · Computer Science 2013-05-14 Fabian Pedregosa , Michael Eickenberg , Bertrand Thirion , Alexandre Gramfort

Lumbar disc herniation (LDH) is a common musculoskeletal disease that requires magnetic resonance imaging (MRI) for effective clinical management. However, the interpretation of MRI images heavily relies on the expertise of radiologists,…

Image and Video Processing · Electrical Eng. & Systems 2025-04-29 Lingrui Zhang , Liang Guo , Xiao An , Feng Lin , Binlong Zheng , Jiankun Wang , Zhirui Li

Electronic Health Records (EHR) data analysis plays a crucial role in healthcare system quality. Because of its highly complex underlying causality and limited observable nature, causal inference on EHR is quite challenging. Deep Learning…

Machine Learning · Computer Science 2022-10-28 Jia Li , Haoyu Yang , Xiaowei Jia , Vipin Kumar , Michael Steinbach , Gyorgy Simon

We study the problem of treatment effect estimation in randomized experiments with high-dimensional covariate information, and show that essentially any risk-consistent regression adjustment can be used to obtain efficient estimates of the…

Methodology · Statistics 2022-06-08 Stefan Wager , Wenfei Du , Jonathan Taylor , Robert Tibshirani

We consider the problem of learning about and comparing the consequences of dynamic treatment strategies on the basis of observational data. We formulate this within a probabilistic decision-theoretic framework. Our approach is compared…

Statistics Theory · Mathematics 2010-11-16 A. Philip Dawid , Vanessa Didelez

This paper studies regression discontinuity designs (RDD) when linear-in-means spillovers occur between units that are close in their running variable. We show that the RDD estimand depends on the ratio of two terms: (1) the radius over…

Econometrics · Economics 2025-09-16 Eric Auerbach , Yong Cai , Ahnaf Rafi

In Regression Discontinuity (RD) design, self-selection leads to different distributions of covariates on two sides of the policy intervention, which essentially violates the continuity of potential outcome assumption. The standard RD…

Methodology · Statistics 2019-11-22 Sida Peng , Yang Ning

Ventricular Fibrillation (VF) is a malignant cardiac arrhythmia and the leading cause of sudden cardiac death, characterized by disorganized, high-frequency ventricular activity that results in the rapid loss of coordinated pump function…

Biological Physics · Physics 2025-11-04 Artemii Remizov , Sergey Lapin

Influence function, a technique rooted in robust statistics, has been adapted in modern machine learning for a novel application: data attribution -- quantifying how individual training data points affect a model's predictions. However, the…

Machine Learning · Computer Science 2024-12-03 Junwei Deng , Weijing Tang , Jiaqi W. Ma

In this paper, we propose a data-adaptive empirical likelihood-based approach for treatment effect estimation and inference, which overcomes the obstacle of the traditional empirical likelihood-based approaches in the high-dimensional…

Methodology · Statistics 2020-12-15 Wei Liang , Ying Yan

We introduce a framework for estimating causal effects of binary and continuous treatments in high dimensions. We show how posterior distributions of treatment and outcome models can be used together with doubly robust estimators. We…

Methodology · Statistics 2020-10-06 Joseph Antonelli , Georgia Papadogeorgou , Francesca Dominici

Functional limitation after lung resection surgery has been consistently documented in clinical studies, and right ventricle (RV) dysfunction has been hypothesized as a contributing reason. However, the mechanisms of RV dysfunction after…

Tissues and Organs · Quantitative Biology 2025-05-05 Shiting Huang , Sanjay Pant , Sean McGinty , Richard Good , Ben Shelley , Ankush Aggarwal

The linear regression model is widely used in the biomedical and social sciences as well as in policy and business research to adjust for covariates and estimate the average effects of treatments. Behind every causal inference endeavor…

Methodology · Statistics 2024-04-23 Ambarish Chattopadhyay , Noah Greifer , Jose R. Zubizarreta

We study the estimation of distributional treatment effects in randomized experiments with imperfect compliance. When participants do not adhere to their assigned treatments, we leverage treatment assignment as an instrumental variable to…

Methodology · Statistics 2025-10-28 Undral Byambadalai , Tomu Hirata , Tatsushi Oka , Shota Yasui

The presence of hyperreflective foci (HFs) is related to retinal disease progression, and the quantity has proven to be a prognostic factor of visual and anatomical outcome in various retinal diseases. However, lack of efficient…

Artificial Intelligence · Computer Science 2024-08-01 Idowu Paul Okuwobi , Zexuan Ji , Wen Fan , Songtao Yuan , Loza Bekalo , Qiang Chen

Methods that address data shifts usually assume full access to multiple datasets. In the healthcare domain, however, privacy-preserving regulations as well as commercial interests limit data availability and, as a result, researchers can…

Machine Learning · Statistics 2022-05-03 Tal El-Hay , Chen Yanover