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We study objective Bayesian inference for linear regression models with residual errors distributed according to the class of two-piece scale mixtures of normal distributions. These models allow for capturing departures from the usual…

Applications · Statistics 2016-05-09 F. J. Rubio , K. Yu

A novel approach for dealing with censored competing risks regression data is proposed. This is implemented by a mixture of accelerated failure time (AFT) models for a competing risks scenario within a cluster-weighted modelling (CWM)…

Methodology · Statistics 2013-12-04 Utkarsh J. Dang , Paul D. McNicholas

In this paper, we explore a method for treating survival analysis as a classification problem. The method uses a "stacking" idea that collects the features and outcomes of the survival data in a large data frame, and then treats it as a…

Methodology · Statistics 2019-09-27 Chenyang Zhong , Robert Tibshirani

The cumulative incidence is the probability of failure from the cause of interest over a certain time period in the presence of other risks. A semiparametric regression model proposed by Fine and Gray (1999) has become the method of choice…

Methodology · Statistics 2016-03-02 Lu Mao , D. Y. Lin

Background: Choosing the most performing method in terms of outcome prediction or variables selection is a recurring problem in prognosis studies, leading to many publications on methods comparison. But some aspects have received little…

In this paper, we discuss causal inference on the efficacy of a treatment or medication on a time-to-event outcome with competing risks. Although the treatment group can be randomized, there can be confoundings between the compliance and…

Methodology · Statistics 2016-12-06 Cheng Zheng , Ran Dai , Parameswaran Hari , Mei-Jie Zhang

Accurately predicting the survival of cancer patients is crucial for personalized treatment. However, existing studies focus solely on the relationships between samples with known survival risks, without fully leveraging the value of…

Machine Learning · Computer Science 2025-07-23 Hailin Yue , Hulin Kuang , Jin Liu , Junjian Li , Lanlan Wang , Mengshen He , Jianxin Wang

Cell competition is recognized to be instrumental to the dynamics and structure of the tumor-host interface in invasive cancers. In mild competition scenarios, the healthy tissue and cancer cells can coexist. When the competition is…

Populations and Evolution · Quantitative Biology 2022-04-19 Heyrim Cho , Doron Levy

Mathematical models of the real world are simplified representations of complex systems. A caveat to using mathematical models is that predicted causal effects and conditional independences may not be robust under model extensions, limiting…

Methodology · Statistics 2022-08-30 Tineke Blom , Joris M. Mooij

Joint models initially dedicated to a single longitudinal marker and a single time-to-event need to be extended to account for the rich longitudinal data of cohort studies. Multiple causes of clinical progression are indeed usually…

Applications · Statistics 2016-01-26 Cécile Proust-Lima , Jean-François Dartigues , Hélène Jacqmin-Gadda

Antibodies, an essential part of our immune system, develop through an intricate process to bind a wide array of pathogens. This process involves randomly mutating DNA sequences encoding these antibodies to find variants with improved…

Populations and Evolution · Quantitative Biology 2018-09-24 Jean Feng , David A. Shaw , Vladimir N. Minin , Noah Simon , Frederick A. Matsen

Competing risks models for a repairable system subject to several failure modes are discussed. Under minimal repair, it is assumed that each failure mode has a power law intensity. An orthogonal reparametrization is used to obtain an…

The Mixture Cure (MC) models constitute an appropriate and easily interpretable method when studying a time-to-event variable in a population comprised of both susceptible and cured individuals. In literature, those models usually assume…

Methodology · Statistics 2024-12-10 Georgios Karakatsoulis

Colorectal cancer refers to the cancer from the dentate line to the junction of rectosigmoid colon, which is one of the most common malignant tumors of the digestive tract. The treatment of colorectal cancer is controversial, so…

Other Quantitative Biology · Quantitative Biology 2022-02-09 Boda Xie

A setting of a trivairate survival function using semi-competing risks concept is proposed. The Stanford Heart Transplant data is reanalyzed using a trivariate Weibull distribution model with the proposed survival function.

Applications · Statistics 2008-10-01 Cheng K. Lee , Jenq-Daw Lee

Win statistics, including the win ratio, net benefit, and win odds, summarize treatment effects on hierarchical composite endpoints by sequentially comparing patient pairs on component outcomes ordered by clinical importance, proceeding to…

Methodology · Statistics 2026-05-27 Xi Fang , Fan Li

Proportional hazards (PH), proportional odds (PO) and accelerated failure time (AFT) models have been widely used to deal with survival data in different fields of knowledge. Despite their popularity, such models are not suitable to handle…

Methodology · Statistics 2019-10-08 Fabio N. Demarqui , Vinicius D. Mayrink

The introduction of machine learning (ML) techniques to the field of survival analysis has increased the flexibility of modeling approaches, and ML based models have become state-of-the-art. These models optimize their own cost functions,…

Machine Learning · Statistics 2023-02-24 Alex Nowak-Vila , Kevin Elgui , Genevieve Robin

This paper proposes a new extension of the linear failure rate (LFR) model to better capture real-world lifetime data. The model incorporates an additional shape parameter to increase flexibility. It helps model the minimum survival time…

Methodology · Statistics 2026-01-13 Suchismita Das , Akul Ameya , Cahyani Karunia Putri

Readmission following discharge from an initial hospitalization is a key marker of quality of health care in the United States. For the most part, readmission has been used to study quality of care for patients with acute health conditions,…

Applications · Statistics 2017-11-21 Kyu Ha Lee , Francesca Dominici , Deborah Schrag , Sebastien Haneuse
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