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Consider the network of all secondary structures of a given RNA sequence, where nodes are connected when the corresponding structures have base pair distance one. The expected degree of the network is the average number of neighbors, where…

Biomolecules · Quantitative Biology 2014-11-04 Peter Clote

A quantitative characterization of the relationship between molecular sequence and structure is essential to improve our understanding of how function emerges. This particular genotype-phenotype map has been often studied in the context of…

Populations and Evolution · Quantitative Biology 2017-04-20 José A. Cuesta , Susanna Manrubia

Let Sn denote the network of all RNA secondary structures of length n, in which undirected edges exist between structures s, t such that t is obtained from s by the addition, removal or shift of a single base pair. Using context-free…

Biomolecules · Quantitative Biology 2018-07-12 Defne Surujon , Yann Ponty , Peter Clote

It is a classical result of Stein and Waterman that the asymptotic number of RNA secondary structures is $1.104366 n^{-3/2} 2.618034^n$. In this paper, we study combinatorial asymptotics for two special subclasses of RNA secondary…

Quantitative Methods · Quantitative Biology 2013-06-19 Peter Clote , Evangelos Kranakis , Danny Krizanc , Bruno Salvy

The measurement of the similarity of RNA secondary structures, and in general of contact structures, of a fixed length has several specific applications. For instance, it is used in the analysis of the ensemble of suboptimal secondary…

Discrete Mathematics · Computer Science 2007-05-23 Mercé Llabrés , Francesc Rosselló

This paper discusses the enumeration of two-terminal series-parallel networks, i.e. the number of electrical networks built with n identical elements connected in series or parallel with two-terminal nodes. They frequently occur in applied…

Statistical Mechanics · Physics 2008-02-03 O. Golinelli

The contact map of a protein fold is a graph that represents the patterns of contacts in the fold. It is known that the contact map can be decomposed into stacks and queues. RNA secondary structures are special stacks in which the degree of…

Combinatorics · Mathematics 2014-06-05 William Y. C. Chen , Qiang-Hui Guo , Lisa H. Sun , Jian Wang

It is a classical result of Stein and Waterman that the asymptotic number of RNA secondary structures is $1.104366 \cdot n^{-3/2} \cdot 2.618034^n$. Motivated by the kinetics of RNA secondary structure formation, we are interested in…

Combinatorics · Mathematics 2013-01-01 Éric Fusy , Peter Clote

Given a random RNA secondary structure, $S$, we study RNA sequences having fixed ratios of nuclotides that are compatible with $S$. We perform this analysis for RNA secondary structures subject to various base pairing rules and minimum arc-…

Combinatorics · Mathematics 2016-03-14 Christopher L. Barrett , Thomas J. X. Li , Christian M. Reidys

In this paper, we propose a network whose nodes are labeled by the composite numbers and two nodes are connected by an undirected link if they are relatively prime to each other. As the size of the network increases, the network will be…

Combinatorics · Mathematics 2024-07-22 Md Rahil Miraj , Dibakar Ghosh , Chittaranjan Hens

We prove asymptotic equipartition properties for simple hierarchical structures (modelled as multitype Galton-Watson trees) and networked structures (modelled as randomly coloured random graphs). For example, for large $n$, a networked data…

Information Theory · Computer Science 2013-10-23 Kwabena Doku-Amponsah

A network is scale-free if its connectivity density function is proportional to a power-law distribution. Scale-free networks may provide an explanation for the robustness observed in certain physical and biological phenomena, since the…

Molecular Networks · Quantitative Biology 2018-07-03 Peter Clote

An RNA molecule is structured on several layers. The primary and most obvious structure is its sequence of bases, i.e. a word over the alphabet {A,C,G,U}. The higher structure is a set of one-to-one base-pairings resulting in a…

Data Structures and Algorithms · Computer Science 2007-05-23 Michael Brinkmeier

In this paper we study properties of topological RNA structures, i.e.~RNA contact structures with cross-serial interactions that are filtered by their topological genus. RNA secondary structures within this framework are topological…

Combinatorics · Mathematics 2016-06-23 Thomas J. X. Li , Christian M. Reidys

Recently Yoffe {\it et al.} observed that the average distances between $5'-3'$ ends of RNA molecules are very small and largely independent of sequence length. This observation is based on numerical computations as well as theoretical…

Combinatorics · Mathematics 2012-01-04 Hillary S. W. Han , Christian M. Reidys

The eccentric connectivity index of a connected graph $G$ is the sum over all vertices $v$ of the product $d_{G}(v) e_{G}(v)$, where $d_{G}(v)$ is the degree of $v$ in $G$ and $e_{G}(v)$ is the maximum distance between $v$ and any other…

Discrete Mathematics · Computer Science 2024-03-11 Gauvain Devillez , Alain Hertz , Hadrien Mélot , Pierre Hauweele

We study the richness of the ensemble of graphical structures (i.e., unlabeled graphs) of the one-dimensional random geometric graph model defined by $n$ nodes randomly scattered in $[0,1]$ that connect if they are within the connection…

Information Theory · Computer Science 2022-06-24 Mihai-Alin Badiu , Justin P. Coon

We find conditions for the connectivity of inhomogeneous random graphs with intermediate density. Our results generalize the classical result for G(n, p), when p = c log n/n. We draw n independent points X_i from a general distribution on a…

Probability · Mathematics 2012-10-25 Luc Devroye , Nicolas Fraiman

An RNA sequence is a word over an alphabet on four elements $\{A,C,G,U\}$ called bases. RNA sequences fold into secondary structures where some bases match one another while others remain unpaired. Pseudoknot-free secondary structures can…

Data Structures and Algorithms · Computer Science 2018-03-28 Édouard Bonnet , Paweł Rzążewski , Florian Sikora

In this paper, we analyze the exact asymptotic behavior of the connectivity probability in a random binomial bipartite graph $G(n,m,p)$ under various regimes of the edge probability $p=p(n)$. To determine this probability, a method based on…

Probability · Mathematics 2025-04-16 Boris Chinyaev
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