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The objective of this study is to derive functional networks for the autism spectrum disorder (ASD) population using the group ICA and dictionary learning model together and to classify ASD and typically developing (TD) participants using…
Human brains lie at the core of complex neurobiological systems, where the neurons, circuits, and subsystems interact in enigmatic ways. Understanding the structural and functional mechanisms of the brain has long been an intriguing pursuit…
This paper introduces a novel methodology to integrate human brain connectomics and parcellation for brain tumor segmentation and survival prediction. For segmentation, we utilize an existing brain parcellation atlas in the MNI152 1mm space…
The study of hierarchy in networks of the human brain has been of significant interest among the researchers as numerous studies have pointed out towards a functional hierarchical organization of the human brain. This paper provides a novel…
We study the impact of the brain tractography false positives in the brain connectivity graphs. The representative input database for the analysis is the set of tractograms from the participants on the ISMRM-2015 Tractography Challenge. We…
Resting-state functional magnetic resonance imaging (fMRI) has emerged as a cornerstone for psychiatric diagnosis, yet most approaches rely on pairwise brain cortical or sub-cortical connectivities that overlooks higher-order interactions…
The properties of functional brain networks strongly depend on how their nodes are chosen. Commonly, nodes are defined by Regions of Interest (ROIs), pre-determined groupings of fMRI measurement voxels. Earlier, we have demonstrated that…
Advanced brain imaging techniques make it possible to measure individuals' structural connectomes in large cohort studies non-invasively. The structural connectome is initially shaped by genetics and subsequently refined by the environment.…
Brain activation and connectivity analyses in task-based functional magnetic resonance imaging (fMRI) experiments with multiple subjects are currently at the forefront of data-driven neuroscience. In such experiments, interest often lies in…
Diffusion tractography in brain connectomics often involves tracing axonal trajectories across gray-white matter boundaries in gyral blades of complex cortical convolutions. To date, gyral bias is observed in most tractography algorithms…
Mammalian tissue architecture is central to biological function, and its disruption is a hallmark of disease. Medical imaging techniques can generate large point cloud datasets that capture changes in the cellular composition of such…
The human brain is a complex system requiring both macroscopic and microscopic components for comprehensive understanding. However, mapping nonlinear relationships between these scales remains challenging due to technical limitations and…
In the last two decades, functional magnetic resonance imaging (fMRI) has emerged as one of the most effective technologies in clinical research of the human brain. fMRI allows researchers to study healthy and pathological brains while they…
This article focuses on a multi-modal imaging data application where structural/anatomical information from gray matter (GM) and brain connectivity information in the form of a brain connectome network from functional magnetic resonance…
The human brain is a complex system, and understanding its mechanisms has been a long-standing challenge in neuroscience. The study of the functional connectome, which maps the functional connections between different brain regions, has…
One of the most well-established tools for modeling the brain as a complex system is the functional connectivity network, which examines the correlations between pairs of interacting brain regions. While powerful, the network model is…
Diffusion-weighted magnetic resonance imaging (DW-MRI) allows for non-invasive imaging of the local fiber architecture of the human brain at a millimetric scale. Multiple classical approaches have been proposed to detect both single (e.g.,…
Shape measures have emerged as promising descriptors of white matter tractography, offering complementary insights into anatomical variability and associations with cognitive and clinical phenotypes. However, conventional methods for…
A central question for neuroscience is how to characterize brain representations of perceptual and cognitive content. An ideal characterization should distinguish different functional regions with robustness to noise and idiosyncrasies of…
Brain decoding is a hot spot in cognitive science, which focuses on reconstructing perceptual images from brain activities. Analyzing the correlations of collected data from human brain activities and representing activity patterns are two…