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Our ability to control complex systems is a fundamental challenge of contemporary science. Recently introduced tools to identify the driver nodes, nodes through which we can achieve full control, predict the existence of multiple control…

We present a general computational theory of cancer and its developmental dynamics. The theory is based on a theory of the architecture and function of developmental control networks which guide the formation of multicellular organisms.…

Molecular Networks · Quantitative Biology 2011-11-16 Eric Werner

The co-evolution of network topology and dynamics is studied in an evolutionary Boolean network model that is a simple model of gene regulatory network. We find that a critical state emerges spontaneously resulting from interplay between…

Statistical Mechanics · Physics 2007-05-23 Min Liu , Kevin E. Bassler

We take a unified view of network coding and decentralized control. Precisely speaking, we consider both as linear time-invariant systems by appropriately restricting channels and coding schemes of network coding to be linear…

Optimization and Control · Mathematics 2013-08-26 Se Yong Park , Anant Sahai

Dynamic processes of interacting units on a network are out of equilibrium in general. In the case of a directed tree, the dynamic cavity method provides an efficient tool that characterises the dynamic trajectory of the process for the…

Disordered Systems and Neural Networks · Physics 2022-05-25 Giuseppe Torrisi , Reimer Kühn , Alessia Annibale

Networked systems are systems of interconnected components, in which the dynamics of each component are influenced by the behavior of neighboring components. Examples of networked systems include biological networks, critical…

Systems and Control · Computer Science 2016-06-01 Andrew Clark , Basel Alomair , Linda Bushnell , Radha Poovendran

Seeking effective neural networks is a critical and practical field in deep learning. Besides designing the depth, type of convolution, normalization, and nonlinearities, the topological connectivity of neural networks is also important.…

Computer Vision and Pattern Recognition · Computer Science 2020-08-20 Kun Yuan , Quanquan Li , Jing Shao , Junjie Yan

Random Boolean networks (RBNs) have been a popular model of genetic regulatory networks for more than four decades. However, most RBN studies have been made with random topologies, while real regulatory networks have been found to be…

Cellular Automata and Lattice Gases · Physics 2015-03-17 Rodrigo Poblanno-Balp , Carlos Gershenson

Selective control in a population is the ability to control a member of the population while leaving the other members relatively unaffected. The concept of selective control is developed using cell death or apoptosis in heterogeneous cell…

Quantitative Methods · Quantitative Biology 2014-07-29 Diego Calzolari , Giovanni Paternostro , Patrick L. Harrington , Carlo Piermarocchi , Phillip M. Duxbury

Computational models of biological processes provide one of the most powerful methods for a detailed analysis of the mechanisms that drive the behavior of complex systems. Logic-based modeling has enhanced our understanding and…

Molecular Networks · Quantitative Biology 2022-02-08 John Zobolas , Pedro T. Monteiro , Martin Kuiper , Åsmund Flobak

In this Letter we propose a method to control a set of arbitrary nodes in a directed network such that they follow a synchronous trajectory which is, in general, not shared by the other units of the network. The problem is inspired to those…

Chaotic Dynamics · Physics 2021-01-19 Bruno Ursino , Lucia Valentina Gambuzza , Vito Latora , Mattia Frasca

To maintain homeostasis, living cells process information with networks of interacting molecules. Traditional models for cellular information processing have focused on networks of chemical reactions between molecules. Here, we describe how…

Biological Physics · Physics 2025-08-01 Arvind Murugan , David Zwicker , Charlotta Lorenz , Eric R. Dufresne

Feedback control is an effective strategy for stabilizing a desired state and has been widely adopted in maintaining the stability of systems such as flying birds and power grids. By default, this framework requires continuous control input…

Adaptation and Self-Organizing Systems · Physics 2025-10-14 Yuanzhao Zhang , Sean P. Cornelius

In spite of the recent interest and advances in linear controllability of complex networks, controlling nonlinear network dynamics remains to be an outstanding problem. We develop an experimentally feasible control framework for nonlinear…

Molecular Networks · Quantitative Biology 2015-09-24 Le-Zhi Wang , Ri-Qi Su , Zi-Gang Huang , Xiao Wang , Wenxu Wang , Celso Grebogi , Ying-Cheng Lai

A dynamical system is controllable if by imposing appropriate external signals on a subset of its nodes, it can be driven from any initial state to any desired state in finite time. Here we study the impact of various network…

Physics and Society · Physics 2013-01-16 Márton Pósfai , Yang-Yu Liu , Jean-Jacques Slotine , Albert-László Barabási

Many discrete models of biological networks rely exclusively on Boolean variables and many tools and theorems are available for analysis of strictly Boolean models. However, multilevel variables are often required to account for threshold…

Molecular Networks · Quantitative Biology 2017-05-09 Adrien Fauré , Shizuo Kaji

In this paper, a novel fluid dynamics-based approach to channel modeling, which considers liquid droplets as information carriers instead of molecules in the molecular communication (MC) channel, is proposed for practical macroscale MC…

Signal Processing · Electrical Eng. & Systems 2021-01-05 Fatih Gulec , Baris Atakan

During the last few years an area of active research in the field of complex systems is that of their information storing and processing abilities. Common opinion has it that the most interesting beaviour of these systems is found ``at the…

adap-org · Physics 2007-05-23 Bartolo Luque , Antonio Ferrera

This paper studies the problem of controlling complex networks, that is, the joint problem of selecting a set of control nodes and of designing a control input to steer a network to a target state. For this problem (i) we propose a metric…

Systems and Control · Computer Science 2014-03-04 Fabio Pasqualetti , Sandro Zampieri , Francesco Bullo

The controllability and observability of Boolean control network(BCN) are two fundamental properties. But the verification of latter is much harder than the former. This paper considers the observability of BCN via controllability. First,…

Optimization and Control · Mathematics 2018-01-03 Daizhan Cheng , Changxi Li , Fenghua He
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