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In the 80's, biomechanicians were asked to work on Computer Aided Surgery applications since orthopaedic surgeons were looking for numerical tools able to predict risks of fractures. More recently, biomechanicians started to address soft…

Medical Physics · Physics 2007-09-03 Patrick Schiavone , T. Boudou , J. Ohayon , Y. Payan

We propose a suite of technologies for analyzing the interaction between anisotropic arterial walls and blood flow for subject-specific geometries. Utilizing an established lumen modeling strategy, we present a comprehensive pipeline for…

Medical Physics · Physics 2024-06-21 Yujie Sun , Jiayi Huang , Qingshuang Lu , Xinhai Yue , Xuanming Huang , Wei He , Yun Shi , Ju Liu

State of the art research and treatment of biological tissues require accurate and efficient methods for describing their mechanical properties. Indeed, micromechanics motivated approaches provide a systematic method for elevating relevant…

Soft Condensed Matter · Physics 2012-05-04 Gal deBotton , Tal Oren

This paper introduces the methodology proposed by our group to model the biological soft tissues deformations and to couple these models with Computer-Assisted Surgical (CAS) applications. After designing CAS protocols that mainly focused…

We present a numerical method specifically designed for simulating three-dimensional fluid--structure interaction (FSI) problems based on the reference map technique (RMT). The RMT is a fully Eulerian FSI numerical method that allows fluids…

Fluid Dynamics · Physics 2022-05-18 Yuexia L. Lin , Nicholas J. Derr , Chris H. Rycroft

Dual-Primal Finite Element Tearing and Interconnecting (FETI-DP) algorithms are developed for a 2D Biot model. The model is formulated with mixed-finite elements as a saddle-point problem. The displacement $\mathbf{u}$ and the Darcy flux…

Numerical Analysis · Mathematics 2023-06-23 Pilhwa Lee

Soft biological tissues demonstrate strong time-dependent and strain-rate mechanical behavior, arising from their intrinsic visco-elasticity and fluid-solid interactions (especially at sufficiently large time scales). The time-dependent…

Tissues and Organs · Quantitative Biology 2023-06-09 Thomas Lavigne , Stéphane Urcun , Pierre-Yves Rohan , Giuseppe Sciumè , Davide Baroli , Stéphane P. A. Bordas

Finite element methods based on cut-cells are becoming increasingly popular because of their advantages over formulations based on body-fitted meshes for problems with moving interfaces. In such methods, the cells (or elements) which are…

Computational Engineering, Finance, and Science · Computer Science 2022-07-18 Chennakesava Kadapa , Xinyu Wang , Yue Mei

AFSI is a novel, open-source fluid-structure interaction (FSI) solver that extends the capabilities of the FEniCS finite element library through an immersed boundary (IB) framework. Designed to simulate large deformations in hyperelastic…

Computational Physics · Physics 2025-09-03 Pengfei Ma , Li Cai , Xuan Wang , Hao Gao

The zebrafish is a valuable model organism for studying cardiac development and diseases due to its many shared aspects of genetics and anatomy with humans and ease of experimental manipulations. Computational fluid-structure interaction…

Tissues and Organs · Quantitative Biology 2025-06-23 Alexander D. Kaiser , Jing Wang , Aaron L. Brown , Enbo Zhu , Tzung Hsiai , Alison L. Marsden

Despite recent advances in diagnosis and treatment, atherosclerotic coronary artery diseases remain a leading cause of death worldwide. Various imaging modalities and metrics can detect lesions and predict patients at risk; however,…

Computational Engineering, Finance, and Science · Computer Science 2024-05-24 Ross Straughan , Karim Kadry , Sahil A. Parikh , Elazer R. Edelman , Farhad R. Nezami

Over the last two decades, scientific literature has been blooming with various means of simulating epithelial cell colonies. Each of these simulations can be separated by their respective efficiency (expressed in terms of consumed…

Computational Physics · Physics 2022-12-20 Kevin Höllring , Ana-Sunčana Smith

We present an immersed boundary method to simulate the creeping motion of a rigid particle in a fluid described by the Stokes equations discretized thanks to a finite element strategy on unfitted meshes, called Phi-FEM, that uses the…

Numerical Analysis · Mathematics 2023-01-30 Michel Duprez , Vanessa Lleras , Alexei Lozinski

Purpose Surgical simulations play an increasingly important role in surgeon education and developing algorithms that enable robots to perform surgical subtasks. To model anatomy, Finite Element Method (FEM) simulations have been held as the…

Robotics · Computer Science 2020-03-27 Jie Ying Wu , Peter Kazanzides , Mathias Unberath

We study the impact of using fluid-structure interactions (FSI) to simulate blood flow in a large stenosed artery. We compare typical flow configurations using Navier-Stokes in a rigid geometry setting to a fully coupled FSI model. The…

Computational Physics · Physics 2021-02-01 Lukas Failer , Piotr Minakowski , Thomas Richter

An accurate, physically-based, and differentiable model of soft robots can unlock downstream applications in optimal control. The Finite Element Method (FEM) is an expressive approach for modeling highly deformable structures such as…

Robotics · Computer Science 2022-03-01 Mathieu Dubied , Mike Michelis , Andrew Spielberg , Robert Katzschmann

Understanding the flow of deformable particles such as liquid drops, synthetic capsules and vesicles, and biological cells confined in a small channel is essential to a wide range of potential chemical and biomedical engineering…

Fluid Dynamics · Physics 2020-11-18 J. M. Lyu , Paul G. Chen , G. Boedec , M. Leonetti , M. Jaeger

For the finite element simulation of thin soft biological tissues in dynamics, shell elements, compared to volume elements, can capture the whole tissue thickness at once, and feature larger critical time steps. However, the capabilities of…

Numerical Analysis · Mathematics 2018-01-15 Bahareh Momenan , Michel R. Labrosse

We propose an algorithm for the efficient parallel implementation of elastoplastic problems with hardening based on the so-called TFETI (Total Finite Element Tearing and Interconnecting) domain decomposition method. We consider an…

Numerical Analysis · Mathematics 2014-01-08 M. Čermák , T. Kozubek , S. Sysala , J. Valdman

The immersed finite element-finite difference (IFED) method is a computational approach to modeling interactions between a fluid and an immersed structure. This method uses a finite element (FE) method to approximate the stresses and forces…

Numerical Analysis · Mathematics 2023-02-01 David Wells , Ben Vadala-Roth , Jae H. Lee , Boyce E. Griffith